| Literature DB >> 24824685 |
T E Kononova1, O I Urazova, V V Novitskii, E G Churina, Yu V Kolobovnikova, M V Ignatov, P A Zakharova, O V Pechenova.
Abstract
Increased content of CD4(+)CD161(+)IL-17A(+) Th17 lymphocytes in the peripheral blood was found in patients with pulmonary tuberculosis irrespective of the clinical form (infiltrative, disseminated) and variant of the disease (drug-sensitive, drug-resistant). The elevated content of Th17 cells in pulmonary tuberculosis is associated with hypersecretion of Th17-associated cytokines IL-17A and IL-22 in vitro that was most pronounced (in case of IL-17A) in patients with disseminated pulmonary tuberculosis.Entities:
Mesh：
Substances：
Year: 2014 PMID： 24824685 DOI： 10.1007/s10517-014-2438-8
Source DB: PubMed Journal: Bull Exp Biol Med ISSN： 0007-4888 Impact factor: 0.804