Literature DB >> 24824440

Alkylations and hydroxymethylations of pyrazines via green Minisci-type reactions.

Bjorn Bohman1, Benjamin Berntsson, Ruby C M Dixon, Craig D Stewart, Russell A Barrow.   

Abstract

A new general methodology utilizing Minisci-type chemistry has been developed that cleanly and efficiently prepares alkyl- and (hydroxymethyl)pyrazines. The new methods eliminate toxic catalysts and halogenated solvents, providing a greatly improved route to these natural products which are prevalent in many natural systems as bacterial volatiles, plant volatiles, and insect pheromones.

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Year:  2014        PMID: 24824440     DOI: 10.1021/ol500776j

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  6 in total

1.  Late-Stage C-H Alkylation of Heterocycles and 1,4-Quinones via Oxidative Homolysis of 1,4-Dihydropyridines.

Authors:  Álvaro Gutiérrez-Bonet; Camille Remeur; Jennifer K Matsui; Gary A Molander
Journal:  J Am Chem Soc       Date:  2017-08-23       Impact factor: 15.419

2.  Drakolide Structure-activity Relationships for Sexual Attraction of Zeleboria Wasp Pollinator.

Authors:  Björn Bohman; Monica M Y Tan; Gavin R Flematti; Rod Peakall
Journal:  J Chem Ecol       Date:  2022-01-31       Impact factor: 2.626

3.  Parapheromones for Thynnine Wasps.

Authors:  Björn Bohman; Amir Karton; Ruby C M Dixon; Russell A Barrow; Rod Peakall
Journal:  J Chem Ecol       Date:  2015-12-14       Impact factor: 2.626

4.  Ketones and aldehydes as alkyl radical equivalents for C─H functionalization of heteroarenes.

Authors:  Jianyang Dong; Zhen Wang; Xiaochen Wang; Hongjian Song; Yuxiu Liu; Qingmin Wang
Journal:  Sci Adv       Date:  2019-10-11       Impact factor: 14.957

5.  Visible light-induced direct α C-H functionalization of alcohols.

Authors:  Linbin Niu; Jiamei Liu; Xing-An Liang; Shengchun Wang; Aiwen Lei
Journal:  Nat Commun       Date:  2019-01-28       Impact factor: 14.919

6.  The Ag-promoted α-C-H arylation of alcohols.

Authors:  Shoufeng Wang; Shuya Xing; Yingying Zhang; Yafei Fan; Huaiqing Zhao; Jianfeng Wang; Shuxiang Zhang; Wengui Wang
Journal:  RSC Adv       Date:  2019-12-17       Impact factor: 4.036

  6 in total

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