| Literature DB >> 24823781 |
Wen-Ling Chan1, Jan-Gowth Chang.
Abstract
Pseudogenes were once considered genomic fossils, but recent studies indicate that they may function as gene regulators through the generation of endogenous small interfering RNAs (esiRNAs), antisense RNAs, and decoys for microRNAs. In this review, we summarize pseudogene study methods, emphasizing relevant publicly available resources, and we describe a systematic pipeline to identify pseudogene-derived esiRNAs and their targets, which can lead to a deeper understanding of pseudogene function.Mesh：
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Year: 2014 PMID： 24823781 DOI： 10.1007/978-1-4939-0835-6_15
Source DB: PubMed Journal: Methods Mol Biol ISSN： 1064-3745