Literature DB >> 24818765

Pulmonary drug delivery by powder aerosols.

Michael Yifei Yang1, John Gar Yan Chan2, Hak-Kim Chan3.   

Abstract

The efficacy of pharmaceutical aerosols relates to its deposition in the clinically relevant regions of the lungs, which can be assessed by in vivo lung deposition studies. Dry powder formulations are popular as devices are portable and aerosolisation does not require a propellant. Over the years, key advancements in dry powder formulation, device design and our understanding on the mechanics of inhaled pharmaceutical aerosol have opened up new opportunities in treatment of diseases through pulmonary drug delivery. This review covers these advancements and future directions for inhaled dry powder aerosols.
Copyright © 2014 Elsevier B.V. All rights reserved.

Keywords:  Dry powder formulation; Dry powder inhaler; Lung deposition; Pharmaceutical aerosol; Pulmonary drug delivery; SPECT imaging

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Substances：

Year:  2014        PMID： 24818765     DOI： 10.1016/j.jconrel.2014.04.055

Source DB:  PubMed          Journal:  J Control Release        ISSN： 0168-3659            Impact factor:   9.776


  30 in total

Review 1.  Administration of dry powders during respiratory supports.

Authors:  Wei-Ren Ke; Rachel Yoon Kyung Chang; Philip Chi Lip Kwok; Patricia Tang; Lan Chen; Donghao Chen; Hak-Kim Chan
Journal:  Ann Transl Med       Date:  2021-04

Review 2.  Cough as an adverse effect on inhalation pharmaceutical products.

Authors:  Rachel Yoon Kyung Chang; Philip Chi Lip Kwok; Sussan Ghassabian; John D Brannan; Heikki O Koskela; Hak-Kim Chan
Journal:  Br J Pharmacol       Date:  2020-08-07       Impact factor: 8.739

Review 3.  Image-Guided Drug Delivery with Single-Photon Emission Computed Tomography: A Review of Literature.

Authors:  Rubel Chakravarty; Hao Hong; Weibo Cai
Journal:  Curr Drug Targets       Date:  2015       Impact factor: 3.465

4.  Manufacture of poly(methyl methacrylate) microspheres using membrane emulsification.

Authors:  Jaiyana Bux; Mohamed S Manga; Timothy N Hunter; Simon Biggs
Journal:  Philos Trans A Math Phys Eng Sci       Date:  2016-07-28       Impact factor: 4.226

5.  The Effect of Spacer Morphology on the Aerosolization Performance of Metered-Dose Inhalers.

Authors:  Sepideh Momeni; Ali Nokhodchi; Saeed Ghanbarzadeh; Hamed Hamishehkar
Journal:  Adv Pharm Bull       Date:  2016-06-30

6.  Dry powder aerosols to co-deliver antibiotics and nutrient dispersion compounds for enhanced bacterial biofilm eradication.

Authors:  S Sommerfeld Ross; S Gharse; L Sanchez; J Fiegel
Journal:  Int J Pharm       Date:  2017-08-04       Impact factor: 5.875

Review 7.  Process optimization and particle engineering of micronized drug powders via milling.

Authors:  A Brunaugh; H D C Smyth
Journal:  Drug Deliv Transl Res       Date:  2018-12       Impact factor: 4.617

Review 8.  Novel Approaches for the Treatment of Pulmonary Tuberculosis.

Authors:  Zhi Ming Tan; Gui Ping Lai; Manisha Pandey; Teerapol Srichana; Mallikarjuna Rao Pichika; Bapi Gorain; Subrat Kumar Bhattamishra; Hira Choudhury
Journal:  Pharmaceutics       Date:  2020-12-10       Impact factor: 6.321

9.  Chitosan-based binary dry powder inhaler carrier with nanometer roughness for improving in vitro and in vivo aerosolization performance.

Authors:  Ying Huang; Zhengwei Huang; Xuejuan Zhang; Ziyu Zhao; Xuan Zhang; Kexin Wang; Cheng Ma; Chune Zhu; Xin Pan; Chuanbin Wu
Journal:  Drug Deliv Transl Res       Date:  2018-10       Impact factor: 4.617

10.  Local dynamics of pharmaceutical powder fluidization using high speed long distance microscopy and particle image velocimetry.

Authors:  K Elserfy; S Cheng; H-K Chan; A Kourmatzis
Journal:  Exp Therm Fluid Sci       Date:  2021-06-01       Impact factor: 3.370
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