AIM: To elucidate an evidence based Single Glucose Challenge test to diagnose Gestational Diabetes Mellitus (GDM). METHOD: This study included 500 pregnant women in 16-32 weeks of gestation. They underwent 75g Oral Glucose Challenge test irrespective of the last meal timing and 2 hr venous blood was drawn. After 3 days they underwent 75g OGTT in the fasting state and their 2 hr blood was drawn. Plasma glucose was estimated in both samples by GOD-POD method. GDM was diagnosed with 2hr Plasma glucose (PG) > or = 7.8 mmol/l (> or = 140 mg/dl) based on WHO criteria. The data was analysed by computer software Microsoft excel for windows and epi-info version 6.0, CDC, Atlanta, GA. RESULTS: Among 500 women, 55(11%) were diagnosed as GDM by WHO criteria. It was observed that there was no statistical difference (p > 0.05) between 2 hr PG of GCT and 2 hr PG of WHO recommended method. CONCLUSION: This Single Glucose Challenge test procedure is cost-effective, evidence based and patient friendly approach to diagnosis Gestational Diabetes Mellitus.
AIM: To elucidate an evidence based Single Glucose Challenge test to diagnose Gestational Diabetes Mellitus (GDM). METHOD: This study included 500 pregnant women in 16-32 weeks of gestation. They underwent 75g Oral Glucose Challenge test irrespective of the last meal timing and 2 hr venous blood was drawn. After 3 days they underwent 75g OGTT in the fasting state and their 2 hr blood was drawn. Plasma glucose was estimated in both samples by GOD-POD method. GDM was diagnosed with 2hr Plasma glucose (PG) > or = 7.8 mmol/l (> or = 140 mg/dl) based on WHO criteria. The data was analysed by computer software Microsoft excel for windows and epi-info version 6.0, CDC, Atlanta, GA. RESULTS: Among 500 women, 55(11%) were diagnosed as GDM by WHO criteria. It was observed that there was no statistical difference (p > 0.05) between 2 hr PG of GCT and 2 hr PG of WHO recommended method. CONCLUSION: This Single Glucose Challenge test procedure is cost-effective, evidence based and patient friendly approach to diagnosis Gestational Diabetes Mellitus.
Authors: Reva Tripathi; Divya Verma; Vinod Kumar Gupta; Shakun Tyagi; M Kalaivani; Siddarth Ramji; Y M Mala Journal: Indian J Med Res Date: 2017-02 Impact factor: 2.375