Literature DB >> 24817001

The rational design of a highly sensitive and selective fluorogenic probe for detecting nitric oxide.

Sufang Ma1, De-Cai Fang, Baoming Ning, Minfeng Li, Lan He, Bing Gong.   

Abstract

A rationally designed small-molecule fluorogenic probe for nitric oxide (NO) detection based on a new switching mechanism has been developed. Attaching a NO-responsive dihydropyridine pendant group to a fluorophore led to a probe that displays a very high sensitivity to NO concentrations down to the low nM range and a very high specificity to NO while being insensitive to other oxidative oxygen/nitrogen species that often interfere with the sensing of NO.

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Year:  2014        PMID： 24817001     DOI： 10.1039/c4cc01142b

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  6 in total

1.  Mannich bases of hydroxycoumarins: synthesis, DFT/QTAIM computational study and assessment of biological activity.

Authors:  J Sergio Durand-Niconoff; Erik Ortiz-Blanco; Gabriela Sosa-Ortiz; José L Olivares-Romero; Enrique Juárez-Aguilar; Eva Luz Montoya-Hernández; Cynthia Fernández-Pomares; Ricardo Tovar-Miranda; María Eugenia Castro; Francisco J Melendez; Tomás Guerrero
Journal:  RSC Adv       Date:  2021-09-22       Impact factor: 4.036

2.  Highly specific C-C bond cleavage induced FRET fluorescence for in vivo biological nitric oxide imaging.

Authors:  Hua Li; Deliang Zhang; Mengna Gao; Lumei Huang; Longguang Tang; Zijing Li; Xiaoyuan Chen; Xianzhong Zhang
Journal:  Chem Sci       Date:  2016-11-30       Impact factor: 9.825

3.  An N-nitrosation reactivity-based two-photon fluorescent probe for the specific in situ detection of nitric oxide.

Authors:  Zhiqiang Mao; Hong Jiang; Zhen Li; Cheng Zhong; Wei Zhang; Zhihong Liu
Journal:  Chem Sci       Date:  2017-04-20       Impact factor: 9.825

4.  Selective and sensitive visualization of endogenous nitric oxide in living cells and animals by a Si-rhodamine deoxylactam-based near-infrared fluorescent probe.

Authors:  Yingying Huo; Junfeng Miao; Lingjun Han; Yaping Li; Zhe Li; Yawei Shi; Wei Guo
Journal:  Chem Sci       Date:  2017-08-02       Impact factor: 9.825

5.  Aromatic secondary amine-functionalized fluorescent NO probes: improved detection sensitivity for NO and potential applications in cancer immunotherapy studies.

Authors:  Yingying Huo; Junfeng Miao; Junru Fang; Hu Shi; Juanjuan Wang; Wei Guo
Journal:  Chem Sci       Date:  2018-10-03       Impact factor: 9.825

6.  Theoretical Design of a Two-Photon Fluorescent Probe for Nitric Oxide with Enhanced Emission Induced by Photoninduced Electron Transfer.

Authors:  Yujin Zhang; Jiancai Leng; Wei Hu
Journal:  Sensors (Basel)       Date:  2018-04-25       Impact factor: 3.576
  6 in total

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