| Literature DB >> 24815565 |
Joselin D Tacastacas1, Julie Bray2, Yoon K Cohen3, Joshua Arbesman3, Julian Kim4, Henry B Koon2, Kord Honda3, Kevin D Cooper3, Meg R Gerstenblith3.
Abstract
Mucosal melanomas are aggressive cancers of mucosal surfaces with clinical and pathologic characteristics distinct from cutaneous melanomas, warranting different staging systems and treatment approaches. Surgical resection is performed frequently for the primary tumor, although the utility of lymph node surgery and radiation therapy is not established. Therapies targeted against C-KIT activating mutations, identified in many mucosal melanomas, are emerging as promising treatments.Entities:
Keywords: C-KIT inhibitors; anorectal mucosal melanoma; clinical characteristics; mucosal melanoma of the head and neck; pathology; treatment; urinary tract melanoma; vulvar and vaginal mucosal melanoma
Mesh：
Year: 2014 PMID： 24815565 DOI： 10.1016/j.jaad.2014.03.031
Source DB: PubMed Journal: J Am Acad Dermatol ISSN： 0190-9622 Impact factor: 11.527