Literature DB >> 24815383

The role of nerve growth factor and its receptors in tumorigenesis and cancer pain.

Wenfang Wang1, Jinhua Chen, Xiuli Guo.   

Abstract

The nerve growth factor (NGF) is a growth factor that belongs to the neurotrophin family. NGF has two structurally different receptors, the p75 neurotrophin receptor (p75NTR) and the tropomyosin-related kinase A (TrkA). Interaction of NGF with its receptors regulates a variety of physiological processes of neuronal system. Recent studies have shown that NGF and its receptors were involved in the regulation of tumourigenesis by either supporting or suppressing tumor growth depending on the tumor types. This review summarizes the current views of NGF and its receptors in tumorigenesis and cancer pain.

Entities:  

Mesh：

Substances：

Year:  2014        PMID： 24815383     DOI： 10.5582/bst.8.68

Source DB:  PubMed          Journal:  Biosci Trends        ISSN： 1881-7815            Impact factor:   2.400


  8 in total

1.  Neurotrophic Effects of Mu Bie Zi (Momordica cochinchinensis) Seed Elucidated by High-Throughput Screening of Natural Products for NGF Mimetic Effects in PC-12 Cells.

Authors:  E Mazzio; B Georges; O McTier; Karam F A Soliman
Journal:  Neurochem Res       Date:  2015-04-11       Impact factor: 3.996

2.  Cobra Venom Factor and Ketoprofen Abolish the Antitumor Effect of Nerve Growth Factor from Cobra Venom.

Authors:  Alexey V Osipov; Tatiana I Terpinskaya; Tatiana E Kuznetsova; Elena L Ryzhkovskaya; Vladimir S Lukashevich; Julia A Rudnichenko; Vladimir S Ulashchyk; Vladislav G Starkov; Yuri N Utkin
Journal:  Toxins (Basel)       Date:  2017-09-06       Impact factor: 4.546

3.  Synergistic activity of everolimus and 5-aza-2'-deoxycytidine in medullary thyroid carcinoma cell lines.

Authors:  Giovanni Vitale; Alessandra Dicitore; Daniele Pepe; Davide Gentilini; Elisa S Grassi; Maria O Borghi; Giulia Gelmini; Maria C Cantone; Germano Gaudenzi; Gabriella Misso; Anna M Di Blasio; Leo J Hofland; Michele Caraglia; Luca Persani
Journal:  Mol Oncol       Date:  2017-06-21       Impact factor: 6.603

4.  Nerve growth factor orchestrates NGAL and matrix metalloproteinases activity to promote colorectal cancer metastasis.

Authors:  Y Lei; X He; H Huang; Y He; J Lan; J Yang; W Liu; T Zhang
Journal:  Clin Transl Oncol       Date:  2021-07-13       Impact factor: 3.405

5.  The efficacy of nerve growth factor antibody in a mouse model of neuropathic cancer pain.

Authors:  Masayuki Miyagi; Tetsuhiro Ishikawa; Hiroto Kamoda; Miyako Suzuki; Gen Inoue; Yoshihiro Sakuma; Yasuhiro Oikawa; Kentaro Uchida; Takane Suzuki; Kazuhisa Takahashi; Masashi Takaso; Seiji Ohtori
Journal:  Exp Anim       Date:  2016-05-17

Review 6.  Nerve Growth Factor and Pathogenesis of Leprosy: Review and Update.

Authors:  Tinara Leila de Souza Aarão; Jorge Rodrigues de Sousa; Aline Semblano Carreira Falcão; Luiz Fábio Magno Falcão; Juarez Antônio Simões Quaresma
Journal:  Front Immunol       Date:  2018-05-07       Impact factor: 7.561

7.  Functional effects of TrkA inhibition on system xC--mediated glutamate release and cancer-induced bone pain.

Authors:  Tanya Miladinovic; Robert G Ungard; Katja Linher-Melville; Snezana Popovic; Gurmit Singh
Journal:  Mol Pain       Date:  2018 Jan-Dec       Impact factor: 3.395

8.  Analysis of Gene Expression and Neuronal Phenotype in Neuroscreen-1 (NS-1) Cells.

Authors:  Smritee Pokharel; Chang Hun Lee; Nailya Gilyazova; Gordon C Ibeanu
Journal:  Int J Biomed Investig       Date:  2018-12-17
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.