Gowri Sayi Prasad1, Ashok Bhupali2, Sayi Prasad3, Ajit N Patil4, Yashodhan Deka5. 1. Associate Professor, Dept. of OBGyn, Dr. D.Y. Patil Hospital, Kolhapur, Maharashtra 416006, India. Electronic address: sayi_prasad@rediffmail.com. 2. Chief Cardiologist, Dept. of Cardiology, Apple Saraswati Multispeciality Hospital, Kolhapur, India. 3. Chief Intensivist, Dept. of Intensive Care, Apple Saraswati Multispeciality Hospital, Kolhapur, India. 4. Head of Department, Dept. of OBGyn, Dr. D.Y. Patil Hospital, Kolhapur, India. 5. Post-Graduate Student, Dept. of OBGyn, Dr. D.Y. Patil Hospital, Kolhapur, India.
Abstract
OBJECTIVES: To study the pattern of presentation, course of disease and outcome of pregnancy in Peripartum Cardiomyopathy. METHODS: A prospective study of sixteen cases of PPCM was conducted at Apple Saraswati Multispecialty Hospital and Dr. D.Y. Patil Medical College and Hospital, Kolhapur, Maharashtra, India from January 2006 to December 2012. Data included age distribution, parity, gestational age, symptoms and risk factors. Medical management and pregnancy outcome were documented. Serial echocardiography data was compiled for a period of one year. RESULTS: In our study 9/16 (56%) were primigravidae, 4/16 (25%) had pre-eclamsia and 6/16 (35%) had co-existing hypertension. The difference in Echocardiography parameters observed between recovered and non-recovered patients was significant: Left Ventricular End diastolic dimension (5.6 cm vs 6.06 cm), Left Ventricular Ejection Fraction (28.7% vs 22.4%) and Left Ventricular fractional shortening (17.5% vs 13.4%). Thirteen out of sixteen patients were followed up for a period of one year out of which 61% (8/13) patients recovered completely. There was one mortality. CONCLUSION: PPCM is a diagnosis of exclusion. Majority were young primigravidae presenting postnatally. Pre-eclampsia and hypertension were risk factors. ECHO parameters were reliable predictors of recovery. Future pregnancies are better avoided.
OBJECTIVES: To study the pattern of presentation, course of disease and outcome of pregnancy in Peripartum Cardiomyopathy. METHODS: A prospective study of sixteen cases of PPCM was conducted at Apple Saraswati Multispecialty Hospital and Dr. D.Y. Patil Medical College and Hospital, Kolhapur, Maharashtra, India from January 2006 to December 2012. Data included age distribution, parity, gestational age, symptoms and risk factors. Medical management and pregnancy outcome were documented. Serial echocardiography data was compiled for a period of one year. RESULTS: In our study 9/16 (56%) were primigravidae, 4/16 (25%) had pre-eclamsia and 6/16 (35%) had co-existing hypertension. The difference in Echocardiography parameters observed between recovered and non-recovered patients was significant: Left Ventricular End diastolic dimension (5.6 cm vs 6.06 cm), Left Ventricular Ejection Fraction (28.7% vs 22.4%) and Left Ventricular fractional shortening (17.5% vs 13.4%). Thirteen out of sixteen patients were followed up for a period of one year out of which 61% (8/13) patients recovered completely. There was one mortality. CONCLUSION: PPCM is a diagnosis of exclusion. Majority were young primigravidae presenting postnatally. Pre-eclampsia and hypertension were risk factors. ECHO parameters were reliable predictors of recovery. Future pregnancies are better avoided.
Authors: J G Demakis; S H Rahimtoola; G C Sutton; W R Meadows; P B Szanto; J R Tobin; R M Gunnar Journal: Circulation Date: 1971-12 Impact factor: 29.690
Authors: Muhammad Sanusi; Elina S Momin; Vijayalakshmi Mannan; Tejasvi Kashyap; Muhammad Ahad Pervaiz; Aqsa Akram; Asma A Khan; Abeer O Elshaikh Journal: Cureus Date: 2022-06-20