Literature DB >> 24814115

Study of clinical profile and management of patients with pulmonary embolism - single center study.

S Calwin Davidsingh1, Narayanan Srinivasan1, P Balaji2, U Kalaichelvan2, Ajit Sankaradas Mullasari3.   

Abstract

OBJECTIVE: To study the clinical profile, diagnostic methods and management in patients with symptomatic pulmonary embolism (PE).
METHODS: Retrospective assessment of clinical features and management of patients presenting with symptomatic pulmonary embolism from January 2005 to March 2012.
RESULTS: 35 patients who were newly diagnosed to have pulmonary embolism with a mean age of 52.1 years were included in the study. Dyspnea (91.4%) and syncope (22.8%) were the predominant symptoms. Echocardiography was done in all patients. 30 patients (85.7%) had pulmonary arterial hypertension, 31 patients (88.5%) had evidence of RV dysfunction and 4 patients (16.7%) had evidence of thrombus in PA, RV. Out of 35 patients, 34 patients (97.14%) showed positive d-dimer reports. Among 35 patients, 24 (68.5%) had positive troponin values. V/Q scan was done in 14 patients (40%) and CT pulmonary angiogram (CTPA) was done in 24 patients (68.5%.). Thrombolysis was done is 24 patients (68.5%). All patients received low molecular weight heparin followed by warfarin. Of the 35 patients, 34 (97.1%) were discharged and were under regular follow up for 6 months and one patient died during the hospital stay.
CONCLUSION: Pulmonary embolism is a common problem and can be easily diagnosed provided it is clinically suspected. Early diagnosis and aggressive management is the key to successful outcome.
Copyright © 2014 Cardiological Society of India. Published by Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Anticoagulation; Pulmonary embolism; Spiral CTPA; Thrombolysis; Venous thromboembolism

Mesh:

Substances:

Year:  2014        PMID: 24814115      PMCID: PMC4017391          DOI: 10.1016/j.ihj.2013.12.037

Source DB:  PubMed          Journal:  Indian Heart J        ISSN: 0019-4832


  22 in total

1.  Prevention of VTE in nonsurgical patients: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines.

Authors:  Susan R Kahn; Wendy Lim; Andrew S Dunn; Mary Cushman; Francesco Dentali; Elie A Akl; Deborah J Cook; Alex A Balekian; Russell C Klein; Hoang Le; Sam Schulman; M Hassan Murad
Journal:  Chest       Date:  2012-02       Impact factor: 9.410

Review 2.  Acute pulmonary embolism.

Authors:  Victor F Tapson
Journal:  N Engl J Med       Date:  2008-03-06       Impact factor: 91.245

Review 3.  Risk factors for venous thromboembolism.

Authors:  Samuel Z Goldhaber
Journal:  J Am Coll Cardiol       Date:  2010-06-29       Impact factor: 24.094

4.  Usefulness of D-dimer, blood gas, and respiratory rate measurements for excluding pulmonary embolism.

Authors:  P Egermayer; G I Town; J G Turner; D C Heaton; A L Mee; M E Beard
Journal:  Thorax       Date:  1998-10       Impact factor: 9.139

5.  Diagnosing acute pulmonary embolism: effect of chronic obstructive pulmonary disease on the performance of D-dimer testing, ventilation/perfusion scintigraphy, spiral computed tomographic angiography, and conventional angiography. ANTELOPE Study Group. Advances in New Technologies Evaluating the Localization of Pulmonary Embolism.

Authors:  I J Hartmann; P J Hagen; C F Melissant; P E Postmus; M H Prins
Journal:  Am J Respir Crit Care Med       Date:  2000-12       Impact factor: 21.405

6.  Clinical profile, diagnosis and management of patients presenting with symptomatic pulmonary embolism.

Authors:  R Agarwal; M Gulati; B R Mittal; S K Jindal
Journal:  Indian J Chest Dis Allied Sci       Date:  2006 Apr-Jun

Review 7.  Noninvasive diagnosis of deep venous thrombosis. McMaster Diagnostic Imaging Practice Guidelines Initiative.

Authors:  C Kearon; J A Julian; T E Newman; J S Ginsberg
Journal:  Ann Intern Med       Date:  1998-04-15       Impact factor: 25.391

8.  The role of risk factors in delayed diagnosis of pulmonary embolism.

Authors:  Savas Ozsu; Funda Oztuna; Yilmaz Bulbul; Murat Topbas; Tevfik Ozlu; Polat Kosucu; Asiye Ozsu
Journal:  Am J Emerg Med       Date:  2010-03-09       Impact factor: 2.469

9.  Prognostic value of troponins in acute pulmonary embolism: a meta-analysis.

Authors:  Cecilia Becattini; Maria Cristina Vedovati; Giancarlo Agnelli
Journal:  Circulation       Date:  2007-07-02       Impact factor: 29.690

10.  Screening for pulmonary embolism with a D-dimer assay: do we still need to assess clinical probability as well?

Authors:  Christopher J Hammond; Tajek B Hassan
Journal:  J R Soc Med       Date:  2005-02       Impact factor: 18.000

View more
  3 in total

1.  Clinical, Radiological, and Outcome Characteristics of Acute Pulmonary Embolism: A 5-year Experience from an Academic Tertiary Center.

Authors:  Wanis H Ibrahim; Shaikha D Al-Shokri; Musa S Hussein; Lana M Abu Afifeh; Gowri Karuppasamy; Jessiya V Parambil; Farras M Elasad; Mohammed E Faris; Mohamed S Abdelghani; Ahmed Abdellah; Antoun Kamel; Hafedh Ghazouani; Mushtaq Ahmad; Aisha Aladab; Mohammed I Danjuma; Tasleem Raza
Journal:  Qatar Med J       Date:  2022-05-09

2.  Clinical profile and management of patients with acute pulmonary thromboembolism - a single centre, large observational study from India.

Authors:  Thoddi Ramamurthy Muralidharan; Sankaran Ramesh; Balakrishnan Vinod Kumar; Aditya V Ruia; Mohan Kumar; Akshaya Gopalakrishnan; Gurpreet S Johal; Amit Hooda; Rohit Malhotra; Reza Masoomi; Mahalakshmi Ramadoss; Vinodhini Subramanian; Maria J Kalsingh; Panchanatham Manokar; Jebaraj Rathinasamy; Shanmugasundram Sadhanandham; Jayanthy V Balasubramaniyan; Preetam Krishnamurthy; Jayanthy S Murthy; Sadagopan Thanikachalam; Nagendra Boopathy Senguttuvan
Journal:  Pulm Circ       Date:  2021-02-16       Impact factor: 3.017

3.  Clinical profile, management and outcome of pulmonary embolism in Shahid Gangalal National Heart Centre, Kathmandu, Nepal.

Authors:  Chandra Mani Adhikari; K C Bishal; Sobita Khadka
Journal:  Egypt Heart J       Date:  2017-06-27
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.