Sarah L Letitre1, Eric P de Groot1, Eelco Draaisma2, Paul L P Brand2. 1. Princess Amalia children's centre, Isala Hospital, Zwolle, The Netherlands. 2. Princess Amalia children's centre, Isala Hospital, Zwolle, The Netherlands UMCG Postgraduate School of Medicine, University Medical Centre and University of Groningen, Groningen, The Netherlands.
Abstract
OBJECTIVE: Although asthma has been linked to psychological morbidity, this relationship may be confounded by poor asthma control. We aimed to compare the prevalence of anxiety, depression and low level of self-esteem in children with well-controlled asthma with that of healthy peers. SETTING: Dedicated asthma clinic in a general hospital. PATIENTS: 70 patients with mostly well-controlled asthma and 70 matched healthy controls. INTERVENTIONS: Comprehensive asthma education, management and follow-up for asthma patients. MAIN OUTCOME MEASURES: Validated Dutch versions of the Childhood Depression inventory (CDI), Revised Fear Survey for Children (RFSC), Self Perception Profile for Children (SPC-C) and Adolescents (SPC-A) and State-Trait Anxiety Inventory for Children (STAIC). Asthma control assessed by asthma control questionnaire. RESULTS: No significant differences were found in total scores between asthmatics and controls (95% CI for difference -0.2 to 2.9 for CDI, -5.9 to 11.2 for RFSC, -19.9 to 6.3 for SPC-C, -24.1 to 5.0 for SPC-A and -2.7 to 0.01 for STAIC). There were also no significant differences between asthmatics and controls in the prevalence of scores exceeding cut-off levels for clinically relevant anxiety (13.3 vs 13.0%, p=0.605), depression (12.9 vs 5.7%, p=0.243) or low self-esteem (21.4 vs 12.9%, p=0.175). A significant correlation was found between poorer asthma control and CDI (p=0.012) and anxiety trait symptoms (p<0.001). CONCLUSIONS: Children with well-controlled asthma enrolled in a comprehensive asthma management programme do not have an increased risk of anxiety, depression and poor self-esteem. Earlier reports of psychological comorbidity in asthma may have been related to inadequately controlled asthma. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.
OBJECTIVE: Although asthma has been linked to psychological morbidity, this relationship may be confounded by poor asthma control. We aimed to compare the prevalence of anxiety, depression and low level of self-esteem in children with well-controlled asthma with that of healthy peers. SETTING: Dedicated asthma clinic in a general hospital. PATIENTS: 70 patients with mostly well-controlled asthma and 70 matched healthy controls. INTERVENTIONS: Comprehensive asthma education, management and follow-up for asthma patients. MAIN OUTCOME MEASURES: Validated Dutch versions of the Childhood Depression inventory (CDI), Revised Fear Survey for Children (RFSC), Self Perception Profile for Children (SPC-C) and Adolescents (SPC-A) and State-Trait Anxiety Inventory for Children (STAIC). Asthma control assessed by asthma control questionnaire. RESULTS: No significant differences were found in total scores between asthmatics and controls (95% CI for difference -0.2 to 2.9 for CDI, -5.9 to 11.2 for RFSC, -19.9 to 6.3 for SPC-C, -24.1 to 5.0 for SPC-A and -2.7 to 0.01 for STAIC). There were also no significant differences between asthmatics and controls in the prevalence of scores exceeding cut-off levels for clinically relevant anxiety (13.3 vs 13.0%, p=0.605), depression (12.9 vs 5.7%, p=0.243) or low self-esteem (21.4 vs 12.9%, p=0.175). A significant correlation was found between poorer asthma control and CDI (p=0.012) and anxiety trait symptoms (p<0.001). CONCLUSIONS:Children with well-controlled asthma enrolled in a comprehensive asthma management programme do not have an increased risk of anxiety, depression and poor self-esteem. Earlier reports of psychological comorbidity in asthma may have been related to inadequately controlled asthma. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.
Authors: Eleanor R Turi; Laura C Reigada; Jianfang Liu; Sarah I Leonard; Jean-Marie Bruzzese Journal: Ann Allergy Asthma Immunol Date: 2021-09-20 Impact factor: 6.347
Authors: Alexandra Kulikova; Josseline Lopez; Anna Antony; Dave A Khan; Donna Persaud; Jasmine Tiro; Elena I Ivleva; Alyson Nakamura; Zena Patel; Shane Tipton; Tressa Lloyd; Karen Allen; Savitoj Kaur; M Seth Owitz; Ray J Pak; Michael S Adragna; Raymond Chankalal; Quratulain Humayun; Heather K Lehman; Bruce D Miller; Beatrice L Wood; E Sherwood Brown Journal: J Allergy Clin Immunol Pract Date: 2021-03-04