Ana M Abrantes1, Erika Litvin Bloom2, David R Strong3, Deborah Riebe4, Bess H Marcus3, Julie Desaulniers5, Kathryn Fokas5, Richard A Brown2. 1. Butler Hospital, Providence, RI; Department of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, RI; ana_abrantes@brown.edu. 2. Butler Hospital, Providence, RI; Department of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, RI; 3. Department of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, RI; Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, CA; 4. Department of Kinesiology, University of Rhode Island, Kingston, RI. 5. Butler Hospital, Providence, RI;
Abstract
INTRODUCTION: Previous exercise intervention studies for smoking cessation have been challenged by a number of methodological limitations that confound the potential efficacy of aerobic exercise for smoking cessation. METHODS: The preliminary efficacy of a behavioral exercise intervention that incorporated features designed to address prior limitations was tested in a randomized controlled trial (RCT). Sixty-one smokers (65.6% female, mean age = 47.3 years, smoked a mean of 19.7 cigarettes/day) were randomized to receive either a 12-week exercise intervention or a 12-week health education contact control. Participants in both conditions received an 8-week telephone-delivered, standard smoking cessation protocol (with the transdermal nicotine patch). Follow-ups were conducted at the end of treatment (EOT), 6- and 12-month timepoints. RESULTS: There were no differences between conditions with respect to the number of weekly exercise or health education sessions attended (9.3±2.8 vs. 9.3±3.0, respectively). While not statistically significant, participants in the exercise condition demonstrated higher verified abstinence rates (EOT: 40% vs. 22.6%, odds ratio [OR] = 2.28; 6- and 12-month follow-ups: 26.7% vs. 12.9%, OR = 2.46). Irrespective of treatment condition, higher levels of moderate-to-vigorous exercise were associated with lower levels of depressive symptoms during the intervention. CONCLUSIONS: The results of this small RCT point toward the benefit of a behavioral exercise intervention designed to address previous methodological limitations for smoking cessation. Given the potential public health impact of the demonstrated efficacy of exercise for smoking cessation, the continued development and optimization of exercise interventions for smokers through larger RCTs merits pursuit.
RCT Entities:
INTRODUCTION: Previous exercise intervention studies for smoking cessation have been challenged by a number of methodological limitations that confound the potential efficacy of aerobic exercise for smoking cessation. METHODS: The preliminary efficacy of a behavioral exercise intervention that incorporated features designed to address prior limitations was tested in a randomized controlled trial (RCT). Sixty-one smokers (65.6% female, mean age = 47.3 years, smoked a mean of 19.7 cigarettes/day) were randomized to receive either a 12-week exercise intervention or a 12-week health education contact control. Participants in both conditions received an 8-week telephone-delivered, standard smoking cessation protocol (with the transdermal nicotine patch). Follow-ups were conducted at the end of treatment (EOT), 6- and 12-month timepoints. RESULTS: There were no differences between conditions with respect to the number of weekly exercise or health education sessions attended (9.3±2.8 vs. 9.3±3.0, respectively). While not statistically significant, participants in the exercise condition demonstrated higher verified abstinence rates (EOT: 40% vs. 22.6%, odds ratio [OR] = 2.28; 6- and 12-month follow-ups: 26.7% vs. 12.9%, OR = 2.46). Irrespective of treatment condition, higher levels of moderate-to-vigorous exercise were associated with lower levels of depressive symptoms during the intervention. CONCLUSIONS: The results of this small RCT point toward the benefit of a behavioral exercise intervention designed to address previous methodological limitations for smoking cessation. Given the potential public health impact of the demonstrated efficacy of exercise for smoking cessation, the continued development and optimization of exercise interventions for smokers through larger RCTs merits pursuit.
Authors: Ana M Abrantes; Samantha G Farris; Haruka Minami; David R Strong; Deborah Riebe; Richard A Brown Journal: Nicotine Tob Res Date: 2018-04-02 Impact factor: 4.244
Authors: Erika Litvin Bloom; Haruka Minami; Richard A Brown; David R Strong; Deborah Riebe; Ana M Abrantes Journal: Psychol Health Med Date: 2017-01-19 Impact factor: 2.423
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Authors: L A Uebelacker; G Tremont; L T Gillette; G Epstein-Lubow; D R Strong; A M Abrantes; A R Tyrka; T Tran; B A Gaudiano; I W Miller Journal: Psychol Med Date: 2017-04-06 Impact factor: 7.723
Authors: Samantha G Farris; Michelle L Davis; David Rosenfield; Brooke Y Kauffman; Scarlett O Baird; Mark B Powers; Michael W Otto; Bess H Marcus; Timothy S Church; Jasper A J Smits; Michael J Zvolensky Journal: Ment Health Phys Act Date: 2016-05-10
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