Literature DB >> 24811790

Current and potential epigenetic targets in multiple myeloma.

Charlotte Pawlyn1, Martin F Kaiser, Faith E Davies, Gareth J Morgan.   

Abstract

Despite recent advances in therapy, subgroups of multiple myeloma continue to have a poor prognosis. Numerous epigenetic changes have been described and occur as both etiologic and secondary events, making myeloma a good disease in which to understand the role of epigenetic therapies. Here, we describe a number of current and potential epigenetic targets in myeloma.

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Year:  2014        PMID： 24811790     DOI： 10.2217/epi.14.12

Source DB:  PubMed          Journal:  Epigenomics        ISSN： 1750-192X            Impact factor:   4.778


  4 in total

1.  The Spectrum and Clinical Impact of Epigenetic Modifier Mutations in Myeloma.

Authors:  Charlotte Pawlyn; Martin F Kaiser; Christoph Heuck; Lorenzo Melchor; Christopher P Wardell; Alex Murison; Shweta S Chavan; David C Johnson; Dil B Begum; Nasrin M Dahir; Paula Z Proszek; David A Cairns; Eileen M Boyle; John R Jones; Gordon Cook; Mark T Drayson; Roger G Owen; Walter M Gregory; Graham H Jackson; Bart Barlogie; Faith E Davies; Brian A Walker; Gareth J Morgan
Journal:  Clin Cancer Res       Date:  2016-05-27       Impact factor: 12.531

2.  Overexpression of EZH2 in multiple myeloma is associated with poor prognosis and dysregulation of cell cycle control.

Authors:  C Pawlyn; M D Bright; A F Buros; C K Stein; Z Walters; L I Aronson; F Mirabella; J R Jones; M F Kaiser; B A Walker; G H Jackson; P A Clarke; P L Bergsagel; P Workman; M Chesi; G J Morgan; F E Davies
Journal:  Blood Cancer J       Date:  2017-03-31       Impact factor: 11.037

Review 3.  Insights into high-risk multiple myeloma from an analysis of the role of PHF19 in cancer.

Authors:  Hussein Ghamlouch; Eileen M Boyle; Patrick Blaney; Yubao Wang; Jinyoung Choi; Louis Williams; Michael Bauer; Daniel Auclair; Benedetto Bruno; Brian A Walker; Faith E Davies; Gareth J Morgan
Journal:  J Exp Clin Cancer Res       Date:  2021-12-02

4.  Genome-wide association study identifies multiple susceptibility loci for multiple myeloma.

Authors:  Jonathan S Mitchell; Ni Li; Niels Weinhold; Asta Försti; Mina Ali; Mark van Duin; Gudmar Thorleifsson; David C Johnson; Bowang Chen; Britt-Marie Halvarsson; Daniel F Gudbjartsson; Rowan Kuiper; Owen W Stephens; Uta Bertsch; Peter Broderick; Chiara Campo; Hermann Einsele; Walter A Gregory; Urban Gullberg; Marc Henrion; Jens Hillengass; Per Hoffmann; Graham H Jackson; Ellinor Johnsson; Magnus Jöud; Sigurður Y Kristinsson; Stig Lenhoff; Oleg Lenive; Ulf-Henrik Mellqvist; Gabriele Migliorini; Hareth Nahi; Sven Nelander; Jolanta Nickel; Markus M Nöthen; Thorunn Rafnar; Fiona M Ross; Miguel Inacio da Silva Filho; Bhairavi Swaminathan; Hauke Thomsen; Ingemar Turesson; Annette Vangsted; Ulla Vogel; Anders Waage; Brian A Walker; Anna-Karin Wihlborg; Annemiek Broyl; Faith E Davies; Unnur Thorsteinsdottir; Christian Langer; Markus Hansson; Martin Kaiser; Pieter Sonneveld; Kari Stefansson; Gareth J Morgan; Hartmut Goldschmidt; Kari Hemminki; Björn Nilsson; Richard S Houlston
Journal:  Nat Commun       Date:  2016-07-01       Impact factor: 14.919
  4 in total

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