| Literature DB >> 24810245 |
Marvaretta Stevenson1, Jared Christensen, Debra Shoemaker, Traci Foster, William T Barry, Betty C Tong, Momen Wahidi, Scott Shofer, Michael Datto, Geoffrey Ginsburg, Jeffrey Crawford, Thomas D'Amico, Neal Ready.
Abstract
The biopsy collection data from two lung cancer trials that required fresh tumor samples be obtained for microarray analysis were reviewed. In the trial for advanced disease, microarray data were obtained on 50 patient samples, giving an overall success rate of 60.2%. The majority of the specimens were obtained through CT-guided lung biopsies (N = 30). In the trial for early-stage patients, 28 tissue specimens were collected from excess tumor after surgical resection with a success rate of 85.7%. This tissue procurement program documents the feasibility in obtaining fresh tumor specimens prospectively that could be used for molecular testing.Entities:
Keywords: Bioinformatics; Gene profiling; Lung cancer
Mesh:
Substances:
Year: 2014 PMID: 24810245 PMCID: PMC4336177 DOI: 10.3109/07357907.2014.911880
Source DB: PubMed Journal: Cancer Invest ISSN: 0735-7907 Impact factor: 2.176