BACKGROUND: The high consumption of low-fat and nonfat dairy products is associated with reduced risk of high blood pressure. OBJECTIVE: We aimed to investigate whether the solitary addition of nonfat dairy products to the normal routine diet was capable of lowering blood pressure in middle-aged and older adults with elevated blood pressure. DESIGN: With the use of a randomized, crossover intervention-study design, 49 adults (56% women) with elevated blood pressure (mean ± SEM age: 53 ± 2 y; systolic blood pressure: 135 ± 1; diastolic blood pressure: 80 ± 1 mm Hg) underwent a high-dairy condition (+4servings conventional nonfat dairy products/d) and isocaloric no-dairy condition (+4 servings fruit products/d) in which all dairy products were removed. Both dietary conditions lasted 4 wk with a 2-wk washout before crossing over into the alternate condition. RESULTS: The high-dairy condition produced reductions in systolic blood pressure (135 ± 1 to 127 ± 1 mm Hg) and pulse pressure (54 ± 1 to 48 ± 1 mm Hg) (both P < 0.05). The hypotensive effects were observed within 3 wk after the initiation of the dietary intervention and in both casual seated and ambulatory (24-h) measurements (P < 0.05). Pulse pressure was increased after the removal of all dairy products in the no-dairy condition (54 ± 1 to 56 ± 1 mm Hg; P < 0.05). There were no changes in diastolic blood pressure after either dietary condition. CONCLUSION: We concluded that the solitary manipulation of conventional dairy products in the normal routine diet would modulate blood pressure in middle-aged and older adults with prehypertension and hypertension. This trial was registered at clinicaltrials.gov as NCT01577030.
RCT Entities:
BACKGROUND: The high consumption of low-fat and nonfat dairy products is associated with reduced risk of high blood pressure. OBJECTIVE: We aimed to investigate whether the solitary addition of nonfat dairy products to the normal routine diet was capable of lowering blood pressure in middle-aged and older adults with elevated blood pressure. DESIGN: With the use of a randomized, crossover intervention-study design, 49 adults (56% women) with elevated blood pressure (mean ± SEM age: 53 ± 2 y; systolic blood pressure: 135 ± 1; diastolic blood pressure: 80 ± 1 mm Hg) underwent a high-dairy condition (+4 servings conventional nonfat dairy products/d) and isocaloric no-dairy condition (+4 servings fruit products/d) in which all dairy products were removed. Both dietary conditions lasted 4 wk with a 2-wk washout before crossing over into the alternate condition. RESULTS: The high-dairy condition produced reductions in systolic blood pressure (135 ± 1 to 127 ± 1 mm Hg) and pulse pressure (54 ± 1 to 48 ± 1 mm Hg) (both P < 0.05). The hypotensive effects were observed within 3 wk after the initiation of the dietary intervention and in both casual seated and ambulatory (24-h) measurements (P < 0.05). Pulse pressure was increased after the removal of all dairy products in the no-dairy condition (54 ± 1 to 56 ± 1 mm Hg; P < 0.05). There were no changes in diastolic blood pressure after either dietary condition. CONCLUSION: We concluded that the solitary manipulation of conventional dairy products in the normal routine diet would modulate blood pressure in middle-aged and older adults with prehypertension and hypertension. This trial was registered at clinicaltrials.gov as NCT01577030.
Authors: Andrew W Brown; Kathryn A Kaiser; Andrew Keitt; Kevin Fontaine; Madeline Gibson; Barbara A Gower; James M Shikany; Colby J Vorland; Donald C Beitz; Dennis M Bier; J Thomas Brenna; David R Jacobs; Penny Kris-Etherton; Kevin Maki; Michael Miller; Marie-Pierre St-Onge; Margarita Teran-Garcia; David B Allison Journal: Crit Rev Food Sci Nutr Date: 2020-02-19 Impact factor: 11.176
Authors: Daniel R Machin; Samuel I Bloom; Robert A Campbell; Tam T T Phuong; Phillip E Gates; Lisa A Lesniewski; Matthew T Rondina; Anthony J Donato Journal: Am J Physiol Heart Circ Physiol Date: 2018-05-11 Impact factor: 4.733
Authors: Daniel R Machin; Heather L Clifton; Russell S Richardson; D Walter Wray; Anthony J Donato; Tracy M Frech Journal: Clin Exp Rheumatol Date: 2017-09-14 Impact factor: 4.473