Literature DB >> 24807597

Abdominal- versus thigh-based reconstruction of perineal defects in patients with cancer.

John Pang1, Justin M Broyles, Jens Berli, Kate Buretta, Sachin M Shridharani, Danielle H Rochlin, Jonathan E Efron, Justin M Sacks.   

Abstract

BACKGROUND: An abdominoperineal resection is an invasive procedure that leaves the patient with vast pelvic dead space. Traditionally, the vertical rectus abdominus myocutaneous flap is used to reconstruct these defects. Oftentimes, this flap cannot be used because of multiple ostomy placements or previous abdominal surgery. The anterolateral thigh flap can be used; however, the efficacy of this flap has been questioned.
OBJECTIVE: We report a single surgeon's experience with perineal reconstruction in patients with cancer with the use of either the vertical rectus abdominus myocutaneous flap or the anterolateral thigh flap to demonstrate acceptable outcomes with either repair modality.
DESIGN: From 2010 to 2012, 19 consecutive patients with perineal defects secondary to cancer underwent flap reconstruction. A retrospective chart review of prospectively entered data was conducted to determine the frequency of short-term and long-term complications. SETTINGS: This study was conducted at an academic, tertiary-care cancer center. PATIENTS: Patients in the study were patients with cancer who were receiving perineal reconstruction.
INTERVENTIONS: Interventions were surgical and included either abdomen- or thigh-based reconstruction. MAIN OUTCOME MEASURES: The main outcome measures included infection, flap failure, length of stay, and time to radiotherapy.
RESULTS: Of the 19 patients included in our study, 10 underwent anterolateral thigh flaps and 9 underwent vertical rectus abdominus myocutaneous flaps for reconstruction. There were no significant differences in demographics between groups (p > 0.05). Surgical outcomes and complications demonstrated no significant differences in the rate of infection, hematoma, bleeding, or necrosis. The mean length of stay after reconstruction was 9.7 ± 3.4 days (± SD) in the anterolateral thigh flap group and 13.4 ± 7.7 days in the vertical rectus abdominus myocutaneous flap group (p > 0.05). LIMITATIONS: The limitations of this study include a relatively small sample size and retrospective evaluation.
CONCLUSION: This study suggests that the anterolateral thigh flap is an acceptable alternative to the vertical rectus abdominus myocutaneous flap for perineal reconstruction (see Video, Supplemental Digital Content 1, http://links.lww.com/DCR/A134).

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Mesh:

Year:  2014        PMID: 24807597     DOI: 10.1097/DCR.0000000000000103

Source DB:  PubMed          Journal:  Dis Colon Rectum        ISSN: 0012-3706            Impact factor:   4.585


  3 in total

1.  Predictors of Perineal Wound Complications and Prolonged Time to Perineal Wound Healing After Abdominoperineal Resection.

Authors:  Azah A Althumairi; Joseph K Canner; Susan L Gearhart; Bashar Safar; Justin Sacks; Jonathan E Efron
Journal:  World J Surg       Date:  2016-07       Impact factor: 3.352

Review 2.  Perineal hernia repair after abdominoperineal excision or extralevator abdominoperineal excision: a systematic review of the literature.

Authors:  A Balla; G Batista Rodríguez; N Buonomo; C Martinez; P Hernández; J Bollo; E M Targarona
Journal:  Tech Coloproctol       Date:  2017-05-15       Impact factor: 3.781

3.  Pelvic/Perineal Reconstruction: Time to Consider the Anterolateral Thigh Flap as a First-line Option?

Authors:  David Perrault; Cindy Kin; Derrick C Wan; Natalie Kirilcuk; Andrew Shelton; Arash Momeni
Journal:  Plast Reconstr Surg Glob Open       Date:  2020-04-24
  3 in total

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