Literature DB >> 24805817

Wound healing and wound location in critical limb ischemia following endovascular treatment.

Norihiro Kobayashi1, Keisuke Hirano, Masatsugu Nakano, Toshiya Muramatsu, Reiko Tsukahara, Yoshiaki Ito, Hiroshi Ishimori.   

Abstract

BACKGROUND: The differences in wound healing according to wound location remain unclear. METHODS AND
RESULTS: Between April 2007 and October 2011, 138 patients (166 limbs) with critical limb ischemia with tissue loss were treated with endovascular treatment. On these limbs, 177 individual wounds were identified on the foot and were evaluated for wound healing rates and time to healing according to their locations. Wound locations were divided into 3 groups: group T (Toe wounds, n=112), group H (Heel wounds, n=25), and group E (Extensive wounds extending onto the fore- or mid-foot along with dorsum or plantar surfaces, n=40). The mean follow-up period was 23±19 months. At 3, 6, 9, and 12 months, wound healing rates were 51%, 64%, 75%, and 75%, respectively, in group T; 12%, 36%, 36%, and 52%, respectively, in group H; and 0%, 5%, 8%, and 13%, respectively, in group E. The median time to healing was 64 days (interquartile range 25-156 days) in group T, 168 days (interquartile range 123-316 days) in group H, and 267 days (interquartile range 177-316 days) in group E (P=0.038).
CONCLUSIONS: Extensive wounds extending onto the fore- or mid-foot along with dorsum or plantar surfaces were the most difficult type of wound to heal.

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Mesh:

Year:  2014        PMID: 24805817     DOI: 10.1253/circj.cj-14-0171

Source DB:  PubMed          Journal:  Circ J        ISSN: 1346-9843            Impact factor:   2.993


  5 in total

1.  Early-phase wound healing and long-term outcomes of a selective endovascular-first approach for treating Rutherford 5 critical limb ischemia with infrainguinal lesions.

Authors:  Kentaro Inoue; Toshihiro Onohara; Keita Mikasa; Tadashi Furuyama
Journal:  Surg Today       Date:  2016-04-18       Impact factor: 2.549

2.  Clinical features and predictors of patients with critical limb ischemia who responded to autologous mononuclear cell transplantation for therapeutic angiogenesis.

Authors:  Naoyoshi Aoyama; Makoto Nishinari; Shinichi Ohtani; Akifumi Kanai; Chiharu Noda; Mitsuhiro Hirata; Akira Miyamoto; Masafumi Watanabe; Tohru Minamino; Tohru Izumi; Jyunya Ako
Journal:  Heart Vessels       Date:  2017-03-29       Impact factor: 2.037

3.  One-Year Outcomes of Peripheral Endovascular Device Intervention in Critical Limb Ischemia Patients: Sub-Analysis of the LIBERTY 360 Study.

Authors:  Jihad A Mustapha; Zsuzsanna Igyarto; David O'Connor; Ehrin J Armstrong; Anthony R Iorio; Vickie R Driver; Fadi Saab; Ann N Behrens; Brad J Martinsen; George L Adams
Journal:  Vasc Health Risk Manag       Date:  2020-02-10

4.  Wound location is independently associated with adverse outcomes following first-time revascularization for tissue loss.

Authors:  Jeremy D Darling; Thomas F X O'Donnell; Giap H Vu; Anthony V Norman; Emily St John; Lars Stangenberg; Mark C Wyers; Allen D Hamdan; Marc L Schermerhorn
Journal:  J Vasc Surg       Date:  2020-08-29       Impact factor: 4.268

5.  Applicability of Transcutaneous Oxygen Tension Measurement in the Assessment of Chronic Limb-Threatening Ischemia.

Authors:  Bernard Leenstra; Joep Wijnand; Bart Verhoeven; Olivier Koning; Martin Teraa; Marianne C Verhaar; Gert J de Borst
Journal:  Angiology       Date:  2019-08-06       Impact factor: 3.619

  5 in total

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