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Literature DB >> 2480240

Somatomedin-binding proteins: what role do they play in the growth process?

Abstract

The insulin-like growth factors (IGF-I and IGF-II) circulate bound to specific proteins. Two classes of binding proteins have been relatively well characterized differing in size, immunological activity, and physiological function. This review summarizes the more recent data on IGF-binding proteins, focusing on their possible clinical implications.

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Year: 1989 PMID： 2480240 DOI： 10.1007/bf01995850

Source DB: PubMed Journal: Eur J Pediatr ISSN： 0340-6199 Impact factor: 3.183

52 in total

1. Estimation of somatomedin-C levels in normals and patients with pituitary disease by radioimmunoassay.

Authors: R W Furlanetto; L E Underwood; J J Van Wyk; A J D'Ercole
Journal: J Clin Invest Date: 1977-09 Impact factor: 14.808

2. Two immunoreactive binding proteins for insulin-like growth factors in human amniotic fluid: relationship to fetal maturity.

Authors: R C Baxter; J L Martin; M H Wood
Journal: J Clin Endocrinol Metab Date: 1987-09 Impact factor: 5.958

3. Diurnal rhythm of growth hormone-independent binding protein for insulin-like growth factors in human plasma.

Authors: R C Baxter; C T Cowell
Journal: J Clin Endocrinol Metab Date: 1987-09 Impact factor: 5.958

4. Serum levels of the low molecular weight form of insulin-like growth factor binding protein in healthy subjects and patients with growth hormone deficiency, acromegaly and anorexia nervosa.

Authors: K Hall; G Lundin; G Póvoa
Journal: Acta Endocrinol (Copenh) Date: 1988-07

5. Insulin-like growth factor (IGF) and IGF-binding proteins: comparison of human serum and lymph.

Authors: M Binoux; P Hossenlopp
Journal: J Clin Endocrinol Metab Date: 1988-09 Impact factor: 5.958

6. Levels of the small insulin-like growth factor-binding protein are strongly related to those of insulin in prepubertal and pubertal children but only weakly so after puberty.

Authors: J M Holly; C P Smith; D B Dunger; J A Edge; R A Biddlecombe; A J Williams; R Howell; T Chard; M O Savage; L H Rees
Journal: J Endocrinol Date: 1989-05 Impact factor: 4.286

7. Soluble 34K binding protein inhibits the binding of insulin-like growth factor I to its cell receptors in human secretory phase endometrium: evidence for autocrine/paracrine regulation of growth factor action.

Authors: E M Rutanen; F Pekonen; T Mäkinen
Journal: J Clin Endocrinol Metab Date: 1988-01 Impact factor: 5.958

8. Partial purification and characterization of a binding protein for insulin-like activity (ILAs) in human amniotic fluid: a possible inhibitor of insulin-like activity.

Authors: S L Drop; G Valiquette; H J Guyda; M T Corvol; B I Posner
Journal: Acta Endocrinol (Copenh) Date: 1979-03

4. Glucose does not influence the insulin-like growth factor (JGF) binding to carrier proteins (IGFBPs): analysis of rat and human serum by western ligand blotting.

Authors: S Cianfarani; V J Frost; M O Savage; J M Holly
Journal: Experientia Date: 1993-08-15

4 in total

Somatomedin-binding proteins: what role do they play in the growth process?

1. Estimation of somatomedin-C levels in normals and patients with pituitary disease by radioimmunoassay.

2. Two immunoreactive binding proteins for insulin-like growth factors in human amniotic fluid: relationship to fetal maturity.

3. Diurnal rhythm of growth hormone-independent binding protein for insulin-like growth factors in human plasma.

4. Serum levels of the low molecular weight form of insulin-like growth factor binding protein in healthy subjects and patients with growth hormone deficiency, acromegaly and anorexia nervosa.

5. Insulin-like growth factor (IGF) and IGF-binding proteins: comparison of human serum and lymph.

6. Levels of the small insulin-like growth factor-binding protein are strongly related to those of insulin in prepubertal and pubertal children but only weakly so after puberty.

7. Soluble 34K binding protein inhibits the binding of insulin-like growth factor I to its cell receptors in human secretory phase endometrium: evidence for autocrine/paracrine regulation of growth factor action.

8. Partial purification and characterization of a binding protein for insulin-like activity (ILAs) in human amniotic fluid: a possible inhibitor of insulin-like activity.

9. Liberation of immunoreactive somatomedin-C from its binding proteins by proteolytic enzymes and heparin.

10. The effects of insulin and growth hormone on the release of somatomedin by the isolated rat liver.

1. Low birthweight and adult insulin resistance: the "catch-up growth" hypothesis.

2. Growth in patients with mucopolysaccharidosis type III (Sanfilippo disease).

3. Insulin like growth factor-I, insulin like growth factor binding protein-1, and insulin in childhood Crohn's disease.

4. Glucose does not influence the insulin-like growth factor (JGF) binding to carrier proteins (IGFBPs): analysis of rat and human serum by western ligand blotting.