Literature DB >> 24801433

Prophylactic pectoralis major muscle flap in prevention of pharyngocutaneous fistula in total laryngectomy after radiotherapy.

Annie-Kim Gendreau-Lefèvre1, Nathalie Audet1, Scott Maltais1, François Thuot1.   

Abstract

BACKGROUND: The purpose of this study was to assess the utility of the pectoralis major muscle flap (PMMF) in the prevention of pharyngocutaneous fistula for total laryngectomy after radiotherapy (RT)
METHODS: We conducted a retrospective review of 166 patients who underwent a total laryngectomy after RT between 1998 and 2012 at the CHU de Québec.
RESULTS: One hundred fifteen patients underwent a total laryngectomy with primary pharyngeal closure alone and 51 patients received an onlay PMMF. The incidence of pharyngocutaneous fistula in the PMMF group was 14% compared to 36% when only primary closure was done (p = .004). However, the PMMF did not influence the treatment needed for the healing of this complication (p = 1.00). The development of pharyngocutaneous fistula increased the length of stay from 19 to 50 days (p < .0001) and delayed the initiation of oral diet from 15 to 25 days (p = .03).
CONCLUSION: Nonirradiated tissue coverage should be routine in total laryngectomy after RT. PMMF is a good adjunct to prevent pharyngocutaneous fistula.
© 2014 Wiley Periodicals, Inc.

Entities:  

Keywords:  pectoralis major muscle flap; pharyngocutaneous fistula; radiotherapy; salvage laryngectomy; total laryngectomy

Mesh:

Year:  2014        PMID: 24801433     DOI: 10.1002/hed.23742

Source DB:  PubMed          Journal:  Head Neck        ISSN: 1043-3074            Impact factor:   3.147


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