Literature DB >> 24799334

BNCT for advanced or recurrent head and neck cancer.

Teruhito Aihara1, Norimasa Morita2, Nobuhiko Kamitani3, Hiroaki Kumada4, Koji Ono5, Junichi Hiratsuka3, Tamotsu Harada2.   

Abstract

The therapeutic effect of surgery and/or combination of conventional chemoradiotherapy is limited in the patients with recurrent squamous cell carcinoma (SCC) and locally advanced non-squamous cell carcinoma without malignant melanoma (non-SCC) of the head and neck. Currently, clinical trials of BNCT for head and neck cancers are being conducted in some institutes to verify its the effectiveness. BNCT was performed in 10 patients with recurrent SCC, 7 patients with recurrent non-SCC and 3 patients with newly diagnosed non-SCC in our university between October 2003 and September 2007. Eleven patients showed complete remission and 7 patients showed partial remission of irradiated site. The effective rate [(CR+PR)/total cases] was 90%. No severe acute or chronic normal-tissue reactions were observed in any patients. BNCT is effective and safe in the patients with recurrent SCC and locally advanced non-SCC.
Copyright © 2014 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  BNCT; Head and neck cancer; Locally advanced non-SCC; Recurrent SCC

Mesh：

Year:  2014        PMID： 24799334     DOI： 10.1016/j.apradiso.2014.04.007

Source DB:  PubMed          Journal:  Appl Radiat Isot        ISSN： 0969-8043            Impact factor:   1.513


  15 in total

1.  Electroporation optimizes the uptake of boron-10 by tumor for boron neutron capture therapy (BNCT) mediated by GB-10: a boron biodistribution study in the hamster cheek pouch oral cancer model.

Authors:  Marcela A Garabalino; Nahuel Olaiz; Agustina Portu; Gisela Saint Martin; Silvia I Thorp; Emiliano C C Pozzi; Paula Curotto; María E Itoiz; Andrea Monti Hughes; Lucas L Colombo; David W Nigg; Verónica A Trivillin; Guillermo Marshall; Amanda E Schwint
Journal:  Radiat Environ Biophys       Date:  2019-05-23       Impact factor: 1.925

Review 2.  Boron neutron capture therapy (BNCT): a unique role in radiotherapy with a view to entering the accelerator-based BNCT era.

Authors:  Minoru Suzuki
Journal:  Int J Clin Oncol       Date:  2019-06-05       Impact factor: 3.402

3.  Determining a methodology of dosimetric quality assurance for commercially available accelerator-based boron neutron capture therapy system.

Authors:  Katsumi Hirose; Takahiro Kato; Takaomi Harada; Tomoaki Motoyanagi; Hiroki Tanaka; Akihiko Takeuchi; Ryohei Kato; Shinya Komori; Yuhei Yamazaki; Kazuhiro Arai; Noriyuki Kadoya; Mariko Sato; Yoshihiro Takai
Journal:  J Radiat Res       Date:  2022-07-19       Impact factor: 2.438

Review 4.  A Critical Review of Radiation Therapy: From Particle Beam Therapy (Proton, Carbon, and BNCT) to Beyond.

Authors:  Yoshitaka Matsumoto; Nobuyoshi Fukumitsu; Hitoshi Ishikawa; Kei Nakai; Hideyuki Sakurai
Journal:  J Pers Med       Date:  2021-08-23

5.  Evaluation of radioactivity in the bodies of mice induced by neutron exposure from an epi-thermal neutron source of an accelerator-based boron neutron capture therapy system.

Authors:  Satoshi Nakamura; Shoji Imamichi; Kazuyoshi Masumoto; Masashi Ito; Akihisa Wakita; Hiroyuki Okamoto; Shie Nishioka; Kotaro Iijima; Kazuma Kobayashi; Yoshihisa Abe; Hiroshi Igaki; Kazuyoshi Kurita; Teiji Nishio; Mitsuko Masutani; Jun Itami
Journal:  Proc Jpn Acad Ser B Phys Biol Sci       Date:  2017       Impact factor: 3.493

Review 6.  Boron Neutron Capture Therapy: A Review of Clinical Applications.

Authors:  Timothy D Malouff; Danushka S Seneviratne; Daniel K Ebner; William C Stross; Mark R Waddle; Daniel M Trifiletti; Sunil Krishnan
Journal:  Front Oncol       Date:  2021-02-26       Impact factor: 6.244

7.  Mapping the Relative Biological Effectiveness of Proton, Helium and Carbon Ions with High-Throughput Techniques.

Authors:  Lawrence Bronk; Fada Guan; Darshana Patel; Duo Ma; Benjamin Kroger; Xiaochun Wang; Kevin Tran; Joycelyn Yiu; Clifford Stephan; Jürgen Debus; Amir Abdollahi; Oliver Jäkel; Radhe Mohan; Uwe Titt; David R Grosshans
Journal:  Cancers (Basel)       Date:  2020-12-05       Impact factor: 6.639

8.  Characterization of the relationship between neutron production and thermal load on a target material in an accelerator-based boron neutron capture therapy system employing a solid-state Li target.

Authors:  Satoshi Nakamura; Hiroshi Igaki; Masashi Ito; Hiroyuki Okamoto; Shie Nishioka; Kotaro Iijima; Hiroki Nakayama; Mihiro Takemori; Shoji Imamichi; Tairo Kashihara; Kana Takahashi; Koji Inaba; Kae Okuma; Naoya Murakami; Yoshihisa Abe; Yuko Nakayama; Mitsuko Masutani; Teiji Nishio; Jun Itami
Journal:  PLoS One       Date:  2019-11-22       Impact factor: 3.240

Review 9.  Boron neutron capture therapy: Current status and future perspectives.

Authors:  Mayya Alexandrovna Dymova; Sergey Yurjevich Taskaev; Vladimir Alexandrovich Richter; Elena Vladimirovna Kuligina
Journal:  Cancer Commun (Lond)       Date:  2020-08-17

10.  Aza-BODIPY: A New Vector for Enhanced Theranostic Boron Neutron Capture Therapy Applications.

Authors:  Ghadir Kalot; Amélie Godard; Benoît Busser; Jacques Pliquett; Mans Broekgaarden; Vincent Motto-Ros; Karl David Wegner; Ute Resch-Genger; Ulli Köster; Franck Denat; Jean-Luc Coll; Ewen Bodio; Christine Goze; Lucie Sancey
Journal:  Cells       Date:  2020-08-25       Impact factor: 6.600
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