| Literature DB >> 24798272 |
J L Del Pozo1, N Fernández-Ros2, E Sáez3, J I Herrero4, J R Yuste2, J M Banales5.
Abstract
Mitochondrial toxicity has been recently suggested to be the underlying mechanism of long-term linezolid-associated toxicity in patients with 16S rRNA genetic polymorphisms. Here, we report for the first time two cases of lactic acidosis due to long-term linezolid exposure in liver transplant recipients who presented an A2706G mitochondrial DNA polymorphism.Entities:
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Year: 2014 PMID: 24798272 PMCID: PMC4068560 DOI: 10.1128/AAC.02856-14
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191