Literature DB >> 24797976

Infectious spondylodiscitis - a case series analysis.

Adam Garkowski1, Agata Zajkowska2, Piotr Czupryna2, Wojciech Lebkowski3, Michał Letmanowski2, Paweł Gołębicki2, Anna Moniuszko2, Andrzej Ustymowicz4, Sławomir Pancewicz2, Joanna Zajkowska2.   

Abstract

PURPOSE: We aimed to describe the clinical and laboratory features as well as diagnostic difficulties in the case series of spondylodiscitis. MATERIALS/
METHODS: We retrospectively reviewed 11 cases of spondylodiscitis. The diagnosis of spondylodiscitis was based on clinical, radiological and microbiological evidence and by the response to antimicrobial therapy.
RESULTS: There were 7 men and 4 women, and the age ranged from 21 to 74 years. Risk factors of spondylodiscitis were observed in 7 patients. The approximate time from onset of symptoms to diagnosis was from 2 to 7 months (median 45 days). Back pain was the most common symptom. The most frequent location of spondylodiscitis was lumbar spine. Pathogens were isolated in 6 cases and were as follows: Staphylococcus aureus (4 cases), Staphylococcus warneri (1 case) and Escherichia coli (1 case). After therapy, all patients had rapid regression of symptoms and no permanent neurological impairments and recurrence of infection were observed.
CONCLUSIONS: Diagnosis of spondylodiscitis is frequently delayed. This disease should be taken into consideration in differential diagnosis in patients with root syndromes accompanied by back pain and usually fever as well as increased values of CRP and ESR.
Copyright © 2014 Medical University of Bialystok. Published by Elsevier Urban & Partner Sp. z o.o. All rights reserved.

Entities:  

Keywords:  Back pain; Infection; Spine; Spondylodiscitis; Vertebral osteomyelitis

Mesh:

Substances:

Year:  2014        PMID: 24797976     DOI: 10.1016/j.advms.2014.02.001

Source DB:  PubMed          Journal:  Adv Med Sci        ISSN: 1896-1126            Impact factor:   3.287


  4 in total

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Authors:  Neil Hopkinson; Kamal Patel
Journal:  Rheumatol Int       Date:  2016-07-14       Impact factor: 2.631

2.  Community Acquired Spondylodiscitis caused by Escherichia Coli; Case Report and Literature Review.

Authors:  F Javier Fonseca Del Pozo; Joaquín Valle Alonso; Miguel Ángel Caracuel Ruiz; Siyamini Vythilingam; Daniel Lopez Ruiz
Journal:  Bull Emerg Trauma       Date:  2016-07

3.  Culture Yield in the Diagnosis of Native Vertebral Osteomyelitis: A Single Tertiary Center Retrospective Case Series With Literature Review.

Authors:  Rachel Weihe; Khaled Taghlabi; Maren Lowrance; Alan Reeves; Sean R Jackson; Douglas C Burton; Wissam El Atrouni
Journal:  Open Forum Infect Dis       Date:  2022-02-07       Impact factor: 3.835

4.  Intervertebral disc cell chondroptosis elicits neutrophil response in Staphylococcus aureus spondylodiscitis.

Authors:  Tiziano A Schweizer; Federica Andreoni; Claudio Acevedo; Thomas C Scheier; Irina Heggli; Ewerton Marques Maggio; Nadia Eberhard; Silvio D Brugger; Stefan Dudli; Annelies S Zinkernagel
Journal:  Front Immunol       Date:  2022-07-28       Impact factor: 8.786

  4 in total

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