| Literature DB >> 24796551 |
Xiaolin Liu1, Naiying Mao, Weisen Yu, Qing Chai, Hui Wang, Weidong Wang, Lijuan Wang, Zhaoguo Wang, Wenbo Xu.
Abstract
To characterize the genetic properties of coxsackievirus A12 (CVA12) strains isolated from hand, foot and mouth disease (HFMD) patients in Qingdao during 2008-2011, the complete genome and VP1 coding region were sequenced and analyzed. Phylogenetic analysis showed that all strains from China clustered into three different branches, suggesting multiple lineages of CVA12 co-circulating in Asia. Sequence analysis indicated a monophyletic group only when the P1 region was examined, indicating possible recombination between CVA12 and other HEV-A serotypes. The emergence of CVA12 involved in an HFMD outbreak in China is a public-health issue.Entities:
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Year: 2014 PMID: 24796551 DOI: 10.1007/s00705-014-2067-6
Source DB: PubMed Journal: Arch Virol ISSN: 0304-8608 Impact factor: 2.574