Literature DB >> 24794263

Use of porous space maintainers in staged mandibular reconstruction.

Allan M Henslee1, Patrick P Spicer1, Sarita R Shah1, Alexander M Tatara1, F Kurtis Kasper1, Antonios G Mikos1, Mark E Wong2.   

Abstract

The success of mandibular reconstructions depends not only on restoring the form and function of lost bone but also on the preservation of the overlying soft tissue layer. In this case study, 5 porous polymethylmethacrylate space maintainers fabricated via patient-specific molds were implanted initially to maintain the vitality of the overlying oral mucosa during staged mandibular reconstructions. Three of the 5 patients healed well; the other 2 patients developed dehiscences, likely due to a thin layer of soft tissue overlying the implant. The results presented provide evidence that a larger investigation of space maintainers fabricated using this method is warranted.
Copyright © 2014 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Implant fabrication; Mandibular reconstruction; Polymethylmethacrylate space maintainer

Mesh:

Substances:

Year:  2014        PMID: 24794263     DOI: 10.1016/j.coms.2014.01.002

Source DB:  PubMed          Journal:  Oral Maxillofac Surg Clin North Am        ISSN: 1042-3699            Impact factor:   2.802


  6 in total

1.  Localized mandibular infection affects remote in vivo bioreactor bone generation.

Authors:  Emma Watson; Brandon T Smith; Mollie M Smoak; Alexander M Tatara; Sarita R Shah; Hannah A Pearce; Katie J Hogan; Jonathan Shum; James C Melville; Issa A Hanna; Nagi Demian; Joseph C Wenke; George N Bennett; Jeroen J J P van den Beucken; John A Jansen; Mark E Wong; Antonios G Mikos
Journal:  Biomaterials       Date:  2020-06-23       Impact factor: 12.479

Review 2.  In vivo bioreactors for mandibular reconstruction.

Authors:  A M Tatara; M E Wong; A G Mikos
Journal:  J Dent Res       Date:  2014-08-19       Impact factor: 6.116

3.  Autologously generated tissue-engineered bone flaps for reconstruction of large mandibular defects in an ovine model.

Authors:  Alexander M Tatara; James D Kretlow; Patrick P Spicer; Steven Lu; Johnny Lam; Wei Liu; Yilin Cao; Guangpeng Liu; John D Jackson; James J Yoo; Anthony Atala; Jeroen J J P van den Beucken; John A Jansen; F Kurtis Kasper; Tang Ho; Nagi Demian; Michael John Miller; Mark E Wong; Antonios G Mikos
Journal:  Tissue Eng Part A       Date:  2015-03-03       Impact factor: 3.845

4.  Econazole-releasing porous space maintainers for fungal periprosthetic joint infection.

Authors:  Alexander M Tatara; Allison J Rozich; Panayiotis D Kontoyiannis; Emma Watson; Nathaniel D Albert; George N Bennett; Antonios G Mikos
Journal:  J Mater Sci Mater Med       Date:  2018-05-11       Impact factor: 3.896

5.  A rapid, flexible method for incorporating controlled antibiotic release into porous polymethylmethacrylate space maintainers for craniofacial reconstruction.

Authors:  P M Mountziaris; S R Shah; J Lam; G N Bennett; A G Mikos
Journal:  Biomater Sci       Date:  2016-01       Impact factor: 6.843

Review 6.  Engineering clinically relevant volumes of vascularized bone.

Authors:  Brianna M Roux; Ming-Huei Cheng; Eric M Brey
Journal:  J Cell Mol Med       Date:  2015-04-15       Impact factor: 5.310

  6 in total

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