Literature DB >> 24794011

Predicting infant neurodevelopmental outcomes using the placenta?

Gerard W O'Keeffe1, Louise C Kenny2.   

Abstract

Identifying those infants most at risk for poor neurodevelopmental outcomes is crucial to allow for targeted surveillance or preventative interventions to be instigated from birth. One intriguing possibility is to use the molecular characteristics of the placenta at birth as a 'molecular barometer' of the in utero experience to predict future infant neurodevelopmental outcomes. Here we highlight the recent advances in the field and discuss the possibilities for an integrated approach across the '-omics' categories.
Copyright © 2014 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  integrated ‘-omics’; neurodevelopment; placenta; screening

Mesh:

Substances:

Year:  2014        PMID: 24794011     DOI: 10.1016/j.molmed.2014.04.005

Source DB:  PubMed          Journal:  Trends Mol Med        ISSN: 1471-4914            Impact factor:   11.951


  5 in total

Review 1.  Epigenetic mechanisms in the placenta related to infant neurodevelopment.

Authors:  Barry M Lester; Carmen J Marsit
Journal:  Epigenomics       Date:  2018-01-30       Impact factor: 4.778

Review 2.  Mechanisms of early placental development in mouse and humans.

Authors:  Myriam Hemberger; Courtney W Hanna; Wendy Dean
Journal:  Nat Rev Genet       Date:  2019-09-18       Impact factor: 53.242

3.  Placental DNA Methylation Related to Both Infant Toenail Mercury and Adverse Neurobehavioral Outcomes.

Authors:  Jennifer Z J Maccani; Devin C Koestler; Barry Lester; E Andrés Houseman; David A Armstrong; Karl T Kelsey; Carmen J Marsit
Journal:  Environ Health Perspect       Date:  2015-03-06       Impact factor: 9.031

4.  Association between hypertensive disorders of pregnancy and risk of autism in offspring: a systematic review and meta-analysis of observational studies.

Authors:  Ruo-Ting Xu; Qing-Xian Chang; Qi-Qiong Wang; Jian Zhang; Lai-Xin Xia; Nanbert Zhong; Yan-Hong Yu; Mei Zhong; Qi-Tao Huang
Journal:  Oncotarget       Date:  2017-12-07

5.  PLGF, a placental marker of fetal brain defects after in utero alcohol exposure.

Authors:  Matthieu Lecuyer; Annie Laquerrière; Soumeya Bekri; Céline Lesueur; Yasmina Ramdani; Sylvie Jégou; Arnaud Uguen; Pascale Marcorelles; Stéphane Marret; Bruno J Gonzalez
Journal:  Acta Neuropathol Commun       Date:  2017-06-06       Impact factor: 7.801

  5 in total

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