Literature DB >> 24792021

"Why do I always see double?" A misdiagnosed case of ocular myasthenia gravis for 10 years.

Uduman Ali Mohamed Yousuf1, B M Yashodhara, Thevi Thanigasalam, Heng Siang Ting.   

Abstract

A 58-year-old man presented with diplopia and partial ptosis for 10 years. It was non-progressive in nature, despite inadequate medical attention the patient received from non-specialists/general practitioners. He did not have fatigability or diurnal variation in weakness and was clinically stable without exacerbations of disease for a decade. He did not have features of Graves's disease, oculopharyngeal dystrophy, cranial nerve paralysis, polymyositis and stroke. The possibility of an atypical presentation of myasthenia gravis (MG) was considered and the patient was evaluated. Ice pack test was negative, Cogan's lid twitch (CLT) test was positive and high titres of acetylcholine receptor antibodies (AChR Ab) suggestive of MG were found. He was treated accordingly with a very good response.

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Year:  2014        PMID: 24792021      PMCID: PMC4024570          DOI: 10.1136/bcr-2013-203488

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  20 in total

1.  The pattern of extra-ocular muscle involvement in ocular myasthenia.

Authors:  Marie Cleary; Graeme John Williams; Richard Andrew Metcalfe
Journal:  Strabismus       Date:  2008 Jan-Mar

2.  Accuracy of the ice test in the diagnosis of myasthenia gravis in patients with ptosis.

Authors:  M Omeed Fakiri; Dénes L J Tavy; Ako Dara Hama-Amin; Paul W Wirtz
Journal:  Muscle Nerve       Date:  2013-09-11       Impact factor: 3.217

Review 3.  Palsies of the trochlear nerve: diagnosis and localization--recent concepts.

Authors:  P W Brazis
Journal:  Mayo Clin Proc       Date:  1993-05       Impact factor: 7.616

4.  The effect of early prednisolone treatment on the generalization rate in ocular myasthenia gravis.

Authors:  H Zach; H Cetin; E Hilger; A Paul; B Wuschitz; R Jung; E Auff; F Zimprich
Journal:  Eur J Neurol       Date:  2012-12-25       Impact factor: 6.089

Review 5.  Medical and surgical treatment for ocular myasthenia.

Authors:  Michael Benatar; Henry Kaminski
Journal:  Cochrane Database Syst Rev       Date:  2012-12-12

6.  An ice test for the diagnosis of myasthenia gravis.

Authors:  K C Golnik; R Pena; A G Lee; E R Eggenberger
Journal:  Ophthalmology       Date:  1999-07       Impact factor: 12.079

7.  Fourth nerve palsy: historical review and study of 215 inpatients.

Authors:  J R Keane
Journal:  Neurology       Date:  1993-12       Impact factor: 9.910

8.  [Clinical and electrophysiological characteristics of myasthenia gravis with thymoma: analysis of 72 patients].

Authors:  Yan Xing; Li-ying Cui; Yu-zhou Guan; Ben-hong Li; Hua Du
Journal:  Zhonghua Yi Xue Za Zhi       Date:  2007-12-04

9.  Ophthalmoplegia in diabetes mellitus: a retrospective study.

Authors:  Domenico Greco; Francesco Gambina; Filippo Maggio
Journal:  Acta Diabetol       Date:  2008-08-29       Impact factor: 4.280

Review 10.  Myasthenia gravis.

Authors:  Vern C Juel; Janice M Massey
Journal:  Orphanet J Rare Dis       Date:  2007-11-06       Impact factor: 4.123

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  1 in total

1.  Starvation-induced diplopia and weakness: a case of beriberi and Wernicke's encephalopathy.

Authors:  Timothy Xin Zhong Tan; Kheng Choon Lim; Charles Chan Chung; Than Aung
Journal:  BMJ Case Rep       Date:  2019-01-03
  1 in total

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