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Literature DB >> 2479128

The return of pancreatic ribonucleases.

Abstract

A decade after losing favor as an 'uninteresting' digestive enzyme, pancreatic ribonuclease has been found to be homologous to a series of extracellular proteins that may influence tumor cell growth, neurological development and biological differentiation. One surprising outcome of these discoveries has been the confirmation of the hypothesis that extracellular 'communicator RNA' is a messenger important in cell growth and differentiation. The only question is: why wasn't this recognized earlier?

Entities: Disease

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Year: 1989 PMID： 2479128 DOI： 10.1016/0968-0004(89)90282-x

Source DB: PubMed Journal: Trends Biochem Sci ISSN： 0968-0004 Impact factor: 13.807

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Cited

14 in total

1. Mutations abrogating the RNase activity in glycoprotein E(rns) of the pestivirus classical swine fever virus lead to virus attenuation.

Authors: G Meyers; A Saalmüller; M Büttner
Journal: J Virol Date: 1999-12 Impact factor: 5.103

Review 2. Examining the evidence for extracellular RNA function in mammals.

Authors: Hannah N Gruner; Michael T McManus
Journal: Nat Rev Genet Date: 2021-04-06 Impact factor: 53.242

3. Two distinct secretory ribonucleases from human cerebrum: purification, characterization and relationships to other ribonucleases.

Authors: T Yasuda; D Nadano; H Takeshita; K Kishi
Journal: Biochem J Date: 1993-12-15 Impact factor: 3.857

4. Secretion of mammalian ribonucleases from Escherichia coli using the signal sequence of murine spleen ribonuclease.

Authors: C H Schein; E Boix; M Haugg; K P Holliger; S Hemmi; G Frank; H Schwalbe
Journal: Biochem J Date: 1992-04-01 Impact factor: 3.857

5. Productive and nonproductive binding to ribonuclease A: X-ray structure of two complexes with uridylyl(2',5')guanosine.

Authors: L Vitagliano; A Merlino; A Zagari; L Mazzarella
Journal: Protein Sci Date: 2000-06 Impact factor: 6.725

6. Deletions at the C-terminus of interferon gamma reduce RNA binding and activation of double-stranded-RNA cleavage by bovine seminal ribonuclease.

Authors: C H Schein; M Haugg
Journal: Biochem J Date: 1995-04-01 Impact factor: 3.857

7. RNase of classical swine fever virus: biochemical characterization and inhibition by virus-neutralizing monoclonal antibodies.

Authors: J M Windisch; R Schneider; R Stark; E Weiland; G Meyers; H J Thiel
Journal: J Virol Date: 1996-01 Impact factor: 5.103