Literature DB >> 24790736

The role of vitamin e in human health and some diseases.

Saliha Rizvi1, Syed T Raza1, Faizal Ahmed1, Absar Ahmad1, Shania Abbas1, Farzana Mahdi1.   

Abstract

Vitamin E is the major lipid-soluble component in the cell antioxidant defence system and is exclusively obtained from the diet. It has numerous important roles within the body because of its antioxidant activity. Oxidation has been linked to numerous possible conditions and diseases, including cancer, ageing, arthritis and cataracts; vitamin E has been shown to be effective against these. Platelet hyperaggregation, which can lead to atherosclerosis, may also be prevented by vitamin E; additionally, it also helps to reduce the production of prostaglandins such as thromboxane, which cause platelet clumping. The current literature review discusses the functions and roles of vitamin E in human health and some diseases as well as the consequences of vitamin E deficiency. The main focus of the review is on the tocopherol class of the vitamers.

Entities:  

Keywords:  Antioxidants; Health; Tocopherols; Vitamin E

Year:  2014        PMID: 24790736      PMCID: PMC3997530     

Source DB:  PubMed          Journal:  Sultan Qaboos Univ Med J        ISSN: 2075-051X


  58 in total

Review 1.  Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity.

Authors:  D Steinberg; S Parthasarathy; T E Carew; J C Khoo; J L Witztum
Journal:  N Engl J Med       Date:  1989-04-06       Impact factor: 91.245

2.  Azidothymidine in the treatment of AIDS.

Authors: 
Journal:  N Engl J Med       Date:  1988-01-28       Impact factor: 91.245

3.  Different isoforms of tocopherols enhance nitric oxide synthase phosphorylation and inhibit human platelet aggregation and lipid peroxidation: implications in therapy with vitamin E.

Authors:  D Li; T Saldeen; F Romeo; J L Mehta
Journal:  J Cardiovasc Pharmacol Ther       Date:  2001-04       Impact factor: 2.457

4.  Antiproliferative and apoptotic effects of tocopherols and tocotrienols on preneoplastic and neoplastic mouse mammary epithelial cells.

Authors:  B S McIntyre; K P Briski; A Gapor; P W Sylvester
Journal:  Proc Soc Exp Biol Med       Date:  2000-09

5.  Suppression of prostate cancer in a transgenic rat model via gamma-tocopherol activation of caspase signaling.

Authors:  Satoru Takahashi; Kentaro Takeshita; Azman Seeni; Satoshi Sugiura; Mingxi Tang; Shin-ya Sato; Hiroki Kuriyama; Masao Nakadate; Koichi Abe; Yoshitaka Maeno; Masataka Nagao; Tomoyuki Shirai
Journal:  Prostate       Date:  2009-05-01       Impact factor: 4.104

6.  Vitamins E and C in the prevention of cardiovascular disease in men: the Physicians' Health Study II randomized controlled trial.

Authors:  Howard D Sesso; Julie E Buring; William G Christen; Tobias Kurth; Charlene Belanger; Jean MacFadyen; Vadim Bubes; JoAnn E Manson; Robert J Glynn; J Michael Gaziano
Journal:  JAMA       Date:  2008-11-09       Impact factor: 56.272

7.  Impaired α-TTP-PIPs interaction underlies familial vitamin E deficiency.

Authors:  Nozomu Kono; Umeharu Ohto; Tatsufumi Hiramatsu; Michiko Urabe; Yasunori Uchida; Yoshinori Satow; Hiroyuki Arai
Journal:  Science       Date:  2013-04-18       Impact factor: 47.728

8.  Gamma-tocopherol inhibits human cancer cell cycle progression and cell proliferation by down-regulation of cyclins.

Authors:  René Gysin; Angelo Azzi; Theresa Visarius
Journal:  FASEB J       Date:  2002-10-04       Impact factor: 5.191

9.  Vitamin E protects nerve cells from amyloid beta protein toxicity.

Authors:  C Behl; J Davis; G M Cole; D Schubert
Journal:  Biochem Biophys Res Commun       Date:  1992-07-31       Impact factor: 3.575

Review 10.  An update on vitamin E, tocopherol and tocotrienol-perspectives.

Authors:  Maria Laura Colombo
Journal:  Molecules       Date:  2010-03-24       Impact factor: 4.411

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  74 in total

1.  Cytoprotective role of vitamin E in porcine adipose-tissue-derived mesenchymal stem cells against hydrogen-peroxide-induced oxidative stress.

Authors:  Fazal Ur Rehman Bhatti; Song Ja Kim; Ae-Kyung Yi; Karen A Hasty; Hongsik Cho
Journal:  Cell Tissue Res       Date:  2018-06-27       Impact factor: 5.249

Review 2.  Vitamins, Are They Safe?

Authors:  Hadi Hamishehkar; Farhad Ranjdoost; Parina Asgharian; Ata Mahmoodpoor; Sarvin Sanaie
Journal:  Adv Pharm Bull       Date:  2016-12-22

3.  Clinics in diagnostic imaging (190). Subacute combined degeneration of the spinal cord (SCD).

Authors:  Mark Christopher Pearce; Garry Choy; Robert Chun Chen
Journal:  Singapore Med J       Date:  2018-09       Impact factor: 1.858

4.  Experience in Nutrition Management of Diabetes-Affected COVID-19 Patients.

Authors:  Behnaz Abiri; Paul C Guest; Mohammadreza Vafa
Journal:  Adv Exp Med Biol       Date:  2021       Impact factor: 2.622

Review 5.  Targeting Mitochondrial Dysfunction for Bipolar Disorder.

Authors:  Maya Kuperberg; Sophie L A Greenebaum; Andrew A Nierenberg
Journal:  Curr Top Behav Neurosci       Date:  2021

6.  Tocopherol Accumulation and Temporal Expression Analysis of VTE1 and VTE5 Gene Family in Fruit of Two Contrasting Avocado Genotypes.

Authors:  Rosalva C Valdez-Agramón; Maribel Valdez-Morales; Melina López-Meyer; Eduardo Sandoval-Castro; Carlos L Calderón-Vázquez
Journal:  Plant Foods Hum Nutr       Date:  2022-05-26       Impact factor: 3.921

Review 7.  The Developing Cerebellum as a Target for Toxic Substances: Protective Role of Antioxidants.

Authors:  Adaze Bijou Enogieru; Oghenakhogie Iroboudu Momodu
Journal:  Cerebellum       Date:  2021-01-21       Impact factor: 3.847

8.  Fecal Metabolomics Reveals Distinct Profiles of Kidney Transplant Recipients and Healthy Controls.

Authors:  Soumaya Kouidhi; Oumaima Zidi; Muhanad Alhujaily; Nessrine Souai; Amor Mosbah; Tareg M Belali; Kais Ghedira; Imene El Kossai; Jamelddine El Manaa; Wissem Mnif; Ameur Cherif
Journal:  Diagnostics (Basel)       Date:  2021-04-29

9.  Vitamin E and selenium improve mesenchymal stem cell conditioned media immunomodulatory effects.

Authors:  Fereshteh Ghasemi; Majid Khoshmirsafa; Elahe Safari; Marzieh Asgari; Mehdi Alemrajabi; Shahrzad Nojehdehi; Samane Khorrami
Journal:  Stem Cell Investig       Date:  2021-05-07

10.  Effect of vitamin E administered to men in infertile couples on sperm and assisted reproduction outcomes: a double-blind randomized study.

Authors:  Roberto Matorras; Jairo Pérez-Sanz; Beatriz Corcóstegui; Irantzu Pérez-Ruiz; Iker Malaina; Sara Quevedo; Fermín Aspichueta; Lorena Crisol; Lorea Martinez-Indart; Begoña Prieto; Antonia Expósito
Journal:  F S Rep       Date:  2020-09-18
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