Literature DB >> 24790669

Ciliary body melanoma - a particularly rare type of ocular tumor. Case report and general considerations.

Mariana Costache1, Oana Maria Patrascu2, Dumitru Adrian2, Diana Costache3, Maria Sajin1, Emil Ungureanu4, Olga Simionescu5.   

Abstract

ABSTRACT: Uveal melanoma is the most common primary malignancy of the eye in white adults. Frequently, uveal melanoma arises from choroid or iris. Ciliary body melanoma is a rare if not exceptional subtype of uveal melanoma. Furthermore, ciliary melanoma is often seen in association with the other two subtypes of uveal melanoma. This paper presents a case of primary ciliary melanoma with invasion of the iris. The patient presented with blurred vision, but this symptom could not doubtless be related with the existence of the tumor, because of the small dimension of the malignancy and the lack of medical history of the patient.This tumor was included in the category of "very small ciliary melanoma", a rare diagnosis considering the fast local invasion and the lack of symptoms in such a small tumor. Histopathological and imunohistochemical examinations confirmed the diagnosis of ciliary melanomaThis type of ocular melanoma has a low prognosis due to early metastases.

Entities:  

Keywords:  ciliary body; genetic predisposition; unfavorable prognosis; uveal melanoma

Year:  2013        PMID: 24790669      PMCID: PMC3968473     

Source DB:  PubMed          Journal:  Maedica (Buchar)        ISSN: 1841-9038


  10 in total

1.  Inflammatory cytokines in eyes with uveal melanoma and relation with macrophage infiltration.

Authors:  Long V Ly; Inge H G Bronkhorst; Els van Beelen; Johannes Vrolijk; Andrew W Taylor; Mieke Versluis; Gregorius P M Luyten; Martine J Jager
Journal:  Invest Ophthalmol Vis Sci       Date:  2010-06-10       Impact factor: 4.799

2.  Malignant melanoma of the ciliary body presenting as extraocular metastasis in the temporalis muscle.

Authors:  Henna Anu-Liisa Oittinen; Michael O'Shaughnessy; Anthony B Cullinane; Catherine Keohane
Journal:  J Clin Pathol       Date:  2007-06-01       Impact factor: 3.411

3.  Uveal melanoma in relation to ultraviolet light exposure and host factors.

Authors:  E A Holly; D A Aston; D H Char; J J Kristiansen; D K Ahn
Journal:  Cancer Res       Date:  1990-09-15       Impact factor: 12.701

4.  BAP1: a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression.

Authors:  D E Jensen; M Proctor; S T Marquis; H P Gardner; S I Ha; L A Chodosh; A M Ishov; N Tommerup; H Vissing; Y Sekido; J Minna; A Borodovsky; D C Schultz; K D Wilkinson; G G Maul; N Barlev; S L Berger; G C Prendergast; F J Rauscher
Journal:  Oncogene       Date:  1998-03-05       Impact factor: 9.867

5.  Ring melanoma of the ciliary body: report on twenty-three patients.

Authors:  Hakan Demirci; Carol L Shields; Jerry A Shields; Santosh G Honavar; Ralph C Eagle
Journal:  Retina       Date:  2002-12       Impact factor: 4.256

6.  Occupational risk factors, ultraviolet radiation, and ocular melanoma: a case-control study in France.

Authors:  P Guénel; L Laforest; D Cyr; J Févotte; S Sabroe; C Dufour; J M Lutz; E Lynge
Journal:  Cancer Causes Control       Date:  2001-06       Impact factor: 2.506

7.  Incidence of uveal melanoma in Europe.

Authors:  Gianni Virgili; Gemma Gatta; Laura Ciccolallo; Riccardo Capocaccia; Annibale Biggeri; Emanuele Crocetti; Jean-Michel Lutz; Eugenio Paci
Journal:  Ophthalmology       Date:  2007-05-11       Impact factor: 12.079

8.  Loss of heterozygosity of chromosome 3 detected with single nucleotide polymorphisms is superior to monosomy 3 for predicting metastasis in uveal melanoma.

Authors:  Michael D Onken; Lori A Worley; Erica Person; Devron H Char; Anne M Bowcock; J William Harbour
Journal:  Clin Cancer Res       Date:  2007-05-15       Impact factor: 12.531

9.  Uveal melanoma.

Authors:  Vasilios P Papastefanou; Victoria M L Cohen
Journal:  J Skin Cancer       Date:  2011-06-30

10.  A comparative transcriptomic analysis of uveal melanoma and normal uveal melanocyte.

Authors:  Jianhong An; Haolei Wan; Xiangtian Zhou; Dan-Ning Hu; Ledan Wang; Lili Hao; Dongsheng Yan; Fanjun Shi; Zhonglou Zhou; Jiao Wang; Songnian Hu; Jun Yu; Jia Qu
Journal:  PLoS One       Date:  2011-01-28       Impact factor: 3.240

  10 in total
  2 in total

1.  A rare case of superior hypopyon with iris neovascularization.

Authors:  Deepti Mahajan; Ravinder Kumar Gupta; Kulbhushan Prakash Chaudhary
Journal:  Oman J Ophthalmol       Date:  2018 Jan-Apr

2.  Ultrasound Biomicroscopy Documented Anterior Uveal Melanoma Regression after Ruthenium-106 Plaque Therapy.

Authors:  Biljana Kuzmanović Elabjer; Mladen Bušić; Andrej Pleše; Mirjana Bjeloš; Daliborka Miletić; Nenad Vukojević
Journal:  Ocul Oncol Pathol       Date:  2021-02-15
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.