Literature DB >> 24790520

Two cases of successful pregnancies after hysteroscopic removal of endometrioid adenocarcinoma grade I, stage IA, in young women with Lynch syndrome.

Ingrid Marton1, Hrvojka Soljacic Vranes2, Vladimir Sparac3, Igor Maricic4, Krunoslav Kuna2, Miroslav Kopjar2.   

Abstract

We present two cases of endometrioid adenocarcinoma grade I, FIGO IA (staging according to the International Federation of Gynecology and Obstetrics) in young women, diagnosed within endometrial polyps. Both patients underwent repeated hysteroscopies and multiple biopsies after initial treatment to medroxyprogesterone one 400 mg daily or the insertion of IUD-LND (intrauterine device-levonorgestrel) for three months. In both of them, all histological samples were negative. Both of them decided that they would try to conceive. The first patient conceived spontaneously and the second patient after IVF (in vitro fertilisation) treatment. They both gave birth to full-term infants. Hysterectomy was recommended to both of our patients, and was carried out. Both of the patients fulfilled both Amsterdam II and revised Bethesda criteria for hereditary non-polyposis colorectal cancer (HNPCC).

Entities:  

Keywords:  Endometrial cancer; Lynch syndrome; hysteroscopy; reproduction

Year:  2014        PMID: 24790520      PMCID: PMC4004308          DOI: 10.5152/jtgga.2013.69379

Source DB:  PubMed          Journal:  J Turk Ger Gynecol Assoc        ISSN: 1309-0380


  15 in total

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Journal:  BJOG       Date:  2009-01       Impact factor: 6.531

2.  Loss of hMSH2 and hMSH6 expression is frequent in sporadic endometrial carcinomas with microsatellite instability: a population-based study.

Authors:  Ingunn Stefansson; Lars A Akslen; Nicola MacDonald; Andy Ryan; Soma Das; Ian J Jacobs; Helga B Salvesen
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3.  Role of hysteroscopy with endometrial biopsy to rule out endometrial cancer in postmenopausal women with abnormal uterine bleeding.

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Review 5.  Intraperitoneal dissemination of endometrial cancer cells after hysteroscopy: a systematic review and meta-analysis.

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Journal:  Int J Gynecol Cancer       Date:  2010-02       Impact factor: 3.437

6.  Cancer statistics, 2013.

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Review 8.  Does hysteroscopy produce intraperitoneal spread of endometrial cancer cells?

Authors:  Ariel Revel; Avi Tsafrir; Shaul O Anteby; Asher Shushan
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  4 in total

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Authors:  Nicole Concin; Carien L Creutzberg; Ignace Vergote; David Cibula; Mansoor Raza Mirza; Simone Marnitz; Jonathan A Ledermann; Tjalling Bosse; Cyrus Chargari; Anna Fagotti; Christina Fotopoulou; Antonio González-Martín; Sigurd F Lax; Domenica Lorusso; Christian Marth; Philippe Morice; Remi A Nout; Dearbhaile E O'Donnell; Denis Querleu; Maria Rosaria Raspollini; Jalid Sehouli; Alina E Sturdza; Alexandra Taylor; Anneke M Westermann; Pauline Wimberger; Nicoletta Colombo; François Planchamp; Xavier Matias-Guiu
Journal:  Virchows Arch       Date:  2021-02       Impact factor: 4.064

Review 2.  Hysteroscopic surgery for conservative management in endometrial cancer: a review of the literature.

Authors:  Sonsoles Alonso; Teresa Castellanos; Fernando Lapuente; Luis Chiva
Journal:  Ecancermedicalscience       Date:  2015-02-03

3.  Challenges in Managing Patients with Hereditary Cancer at Gynecological Services.

Authors:  Mako Ueda; Hiroshi Tsubamoto; Mina Kashima-Morii; Yoshitaka Torii; Mariko Kamihigashi; Yu Wakimoto; Nami Nakagomi; Tomoko Hashimoto-Tamaoki; Hideaki Sawai; Hiroaki Shibahara
Journal:  Obstet Gynecol Int       Date:  2019-05-27

4.  Fertility preserving treatment with hysteroscopic resection followed by progestin therapy in young women with early endometrial cancer.

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Journal:  J Gynecol Oncol       Date:  2016-08-08       Impact factor: 4.401

  4 in total

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