| Literature DB >> 24790520 |
Ingrid Marton1, Hrvojka Soljacic Vranes2, Vladimir Sparac3, Igor Maricic4, Krunoslav Kuna2, Miroslav Kopjar2.
Abstract
We present two cases of endometrioid adenocarcinoma grade I, FIGO IA (staging according to the International Federation of Gynecology and Obstetrics) in young women, diagnosed within endometrial polyps. Both patients underwent repeated hysteroscopies and multiple biopsies after initial treatment to medroxyprogesterone one 400 mg daily or the insertion of IUD-LND (intrauterine device-levonorgestrel) for three months. In both of them, all histological samples were negative. Both of them decided that they would try to conceive. The first patient conceived spontaneously and the second patient after IVF (in vitro fertilisation) treatment. They both gave birth to full-term infants. Hysterectomy was recommended to both of our patients, and was carried out. Both of the patients fulfilled both Amsterdam II and revised Bethesda criteria for hereditary non-polyposis colorectal cancer (HNPCC).Entities:
Keywords: Endometrial cancer; Lynch syndrome; hysteroscopy; reproduction
Year: 2014 PMID: 24790520 PMCID: PMC4004308 DOI: 10.5152/jtgga.2013.69379
Source DB: PubMed Journal: J Turk Ger Gynecol Assoc ISSN: 1309-0380