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Literature DB >> 24789881

Diabetes, aging, and their tissue complications.

Abstract

The inactivation of NO by advanced glycation endproducts (AGEs), which accumulate on tissue proteins as a function of age and hyperglycemia, focused attention on the role of these ubiquitous posttranslational modifications in acquired impairments of vascular reactivity and other signaling processes. This observation occurred during a watershed period of basic and translational research in glycation that encompassed new pathologic phenomena and novel intervention strategies. How has the AGE paradigm for the tissue complications of aging and diabetes fared since the identification of the link between these glycation products and NO inactivation, and what lessons may be offered for future investigations?

Entities: Disease

Mesh：

Substances：

Year: 2014 PMID： 24789881 PMCID： PMC4001559 DOI： 10.1172/JCI75224

Source DB: PubMed Journal: J Clin Invest ISSN： 0021-9738 Impact factor: 14.808

15 in total

1. Biochemistry and molecular cell biology of diabetic complications.

Authors: M Brownlee
Journal: Nature Date: 2001-12-13 Impact factor: 49.962

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Authors: L J Ignarro; G M Buga; K S Wood; R E Byrns; G Chaudhuri
Journal: Proc Natl Acad Sci U S A Date: 1987-12 Impact factor: 11.205

Review 3. Current therapeutic interventions in the glycation pathway: evidence from clinical studies.

Authors: L Engelen; C D A Stehouwer; C G Schalkwijk
Journal: Diabetes Obes Metab Date: 2013-01-25 Impact factor: 6.577

4. Advanced Maillard reaction end products are associated with Alzheimer disease pathology.

Authors: M A Smith; S Taneda; P L Richey; S Miyata; S D Yan; D Stern; L M Sayre; V M Monnier; G Perry
Journal: Proc Natl Acad Sci U S A Date: 1994-06-07 Impact factor: 11.205

5. An agent cleaving glucose-derived protein crosslinks in vitro and in vivo.

Authors: S Vasan; X Zhang; X Zhang; A Kapurniotu; J Bernhagen; S Teichberg; J Basgen; D Wagle; D Shih; I Terlecky; R Bucala; A Cerami; J Egan; P Ulrich
Journal: Nature Date: 1996-07-18 Impact factor: 49.962

6. Advanced glycosylation endproducts block the antiproliferative effect of nitric oxide. Role in the vascular and renal complications of diabetes mellitus.

Authors: M Hogan; A Cerami; R Bucala
Journal: J Clin Invest Date: 1992-09 Impact factor: 14.808

7. Lipid advanced glycosylation: pathway for lipid oxidation in vivo.

Authors: R Bucala; Z Makita; T Koschinsky; A Cerami; H Vlassara
Journal: Proc Natl Acad Sci U S A Date: 1993-07-15 Impact factor: 11.205

8. A role for DNA mutations in diabetes-associated teratogenesis in transgenic embryos.

Authors: A T Lee; A Plump; C DeSimone; A Cerami; R Bucala
Journal: Diabetes Date: 1995-01 Impact factor: 9.461

9. Aminoguanidine prevents diabetes-induced arterial wall protein cross-linking.

Authors: M Brownlee; H Vlassara; A Kooney; P Ulrich; A Cerami
Journal: Science Date: 1986-06-27 Impact factor: 47.728

10. Advanced glycosylation products quench nitric oxide and mediate defective endothelium-dependent vasodilatation in experimental diabetes.

Authors: R Bucala; K J Tracey; A Cerami
Journal: J Clin Invest Date: 1991-02 Impact factor: 14.808

14 in total

Review 1. Consequences of metabolic and oxidative modifications of cartilage tissue.

Authors: John A Hardin; Neil Cobelli; Laura Santambrogio
Journal: Nat Rev Rheumatol Date: 2015-06-02 Impact factor: 20.543

Review 2. Pathogenesis of diabetic cerebral vascular disease complication.

Authors: Ren-Shi Xu
Journal: World J Diabetes Date: 2015-02-15

Review 3. Leonurine: From Gynecologic Medicine to Pleiotropic Agent.

Authors: Yun-Yun Li; Yi-Kong Lin; Xin-Hua Liu; Li Wang; Min Yu; Da-Jin Li; Yi-Zhun Zhu; Mei-Rong Du
Journal: Chin J Integr Med Date: 2019-05-08 Impact factor: 1.978

4. High glucose and palmitic acid induces neuronal senescence by NRSF/REST elevation and the subsequent mTOR-related autophagy suppression.

Authors: Wen-Jiao Xue; Cheng-Feng He; Ren-Yuan Zhou; Xiao-Die Xu; Lv-Xuan Xiang; Jian-Tao Wang; Xin-Ru Wang; Hou-Guang Zhou; Jing-Chun Guo
Journal: Mol Brain Date: 2022-07-18 Impact factor: 4.399

5. RAGE-aptamer Attenuates the Growth and Liver Metastasis of Malignant Melanoma in Nude Mice.

Authors: Nobutaka Nakamura; Takanori Matsui; Yuji Ishibashi; Ami Sotokawauchi; Kei Fukami; Yuichiro Higashimoto; Sho-Ichi Yamagishi
Journal: Mol Med Date: 2017-11-06 Impact factor: 6.354

6. Effect of Source Animal Age upon Macrophage Response to Extracellular Matrix Biomaterials.

Authors: Samuel T LoPresti; Bryan N Brown
Journal: J Immunol Regen Med Date: 2018-04-25

Review 7. Crosstalk between advanced glycation end products (AGEs)-receptor RAGE axis and dipeptidyl peptidase-4-incretin system in diabetic vascular complications.

Authors: Sho-ichi Yamagishi; Kei Fukami; Takanori Matsui
Journal: Cardiovasc Diabetol Date: 2015-01-13 Impact factor: 9.951