Literature DB >> 24785978

Persistent lipid abnormalities in patients with hypertension and dyslipidemia treated with statins: results of the Portuguese hypertensive subpopulation of the Dyslipidemia International Study (DYSIS).

Pedro M Silva1, Salvador M Cardoso, Antonio M Ferreira.   

Abstract

This study aimed to assess the treatment patterns and prevalence of persistent lipid abnormalities in Portuguese hypertensive patients concomitantly treated with statins. Only 25% of the 656 hypertensive patients achieved the blood pressure goals in use during the study period. Similarly, only 33% and 37% attained the recommended levels of total cholesterol<4.5 mmol/L and LDL cholesterol<2.5 mmol/L, respectively. Relatively low doses of medium potency statins were the mainstay of therapy. There seems to be considerable room for improvement through the use of more potent statins, dose up-titration, and/or addition of other lipid-modifying therapies.

Entities:  

Keywords:  Cardiovascular disease; HMG-CoA; dyslipidemia; hypertension; simvastatin; statins

Mesh:

Substances:

Year:  2014        PMID: 24785978     DOI: 10.3109/10641963.2014.913605

Source DB:  PubMed          Journal:  Clin Exp Hypertens        ISSN: 1064-1963            Impact factor:   1.749


  3 in total

Review 1.  The Different Facets of Dyslipidemia and Hypertension in Atherosclerosis.

Authors:  Jessica Hurtubise; Krystie McLellan; Kevin Durr; Oluwadara Onasanya; Daniel Nwabuko; Joseph Fomusi Ndisang
Journal:  Curr Atheroscler Rep       Date:  2016-12       Impact factor: 5.113

2.  Post Hoc Analysis of the CONFIDENCE II, PROTECT I, SHAKE THE HABIT I and SHAKE THE HABIT II Observational Studies in Mild to Moderate Hypertensive Patients Treated with Perindopril and Atorvastatin Concomitantly.

Authors:  John S Sampalis; Eliofotisti Psaradellis; Melissa Stutz; Jenaya Rickard; Emmanouil Rampakakis
Journal:  Drugs R D       Date:  2018-12

Review 3.  The Association between Inflammation and Pulse Wave Velocity in Dyslipidemia: An Evidence-Based Review.

Authors:  Amilia Aminuddin; Md Rizman M L M Lazim; Adila A Hamid; Chua K Hui; Mohd H Mohd Yunus; Jaya Kumar; Azizah Ugusman
Journal:  Mediators Inflamm       Date:  2020-08-18       Impact factor: 4.711

  3 in total

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