Literature DB >> 24785844

Autologous buccal mucosa graft augmentation for foreshortened vagina.

Gwen M Grimsby1, Karen Bradshaw, Linda A Baker.   

Abstract

BACKGROUND: Vaginal foreshortening after pelvic surgery or radiotherapy may lead to dyspareunia and decreased quality of life. Unfortunately, little literature exists regarding treatment options for this debilitating problem. Autologous buccal mucosal grafting has been previously reported for creation of a total neovagina and the repair of postvaginoplasty vaginal stenosis. TECHNIQUE: Autologous buccal mucosa offers several advantages as a replacement material for vaginal reconstruction. Vaginal and oral buccal mucosa are both hairless, moist, nonkeratinized stratified squamous epithelia. Buccal mucosa has a dense layer of elastic fibers, imparting both elasticity and strength, and acquires a robust neovascularity with excellent graft take. The graft material is readily available and donor site scars are hidden in the mouth. EXPERIENCE: A 60-year-old woman had vaginal foreshortening to 4.5 cm 15 years after radical hysterectomy and brachytherapy for endometrial cancer. She was unable to have intercourse despite attempted vaginal dilation. Her foreshortened vagina was successfully augmented with autologous buccal mucosa grafting at the apex, increasing her vaginal length to 8 cm and permitting pain-free intercourse.
CONCLUSION: Even in the face of an altered surgical field after radical hysterectomy and radiation, autologous buccal mucosa is an option for vaginal reconstruction for vaginal foreshortening.

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Year:  2014        PMID: 24785844     DOI: 10.1097/AOG.0000000000000226

Source DB:  PubMed          Journal:  Obstet Gynecol        ISSN: 0029-7844            Impact factor:   7.661


  2 in total

Review 1.  Vaginoplasty with an Autologous Buccal Mucosa Fenestrated Graft in Two Patients with Vaginal Agenesis: A Multidisciplinary Approach and Literature Review.

Authors:  Jessica L Chan; Pamela J Levin; Brian P Ford; David C Stanton; Samantha M Pfeifer
Journal:  J Minim Invasive Gynecol       Date:  2017-02-15       Impact factor: 4.137

2.  Post-operative complications following feminizing genitoplasty in moderate to severe genital atypia: Results from a multicenter, observational prospective cohort study.

Authors:  Avi Baskin; Amy B Wisniewski; Christopher E Aston; Paul Austin; Yee-Ming Chan; Earl Y Cheng; David A Diamond; Allyson Fried; Thomas Kolon; Yegappan Lakshmanan; Pierre Williot; Sabrina Meyer; Theresa Meyer; Bradley Kropp; Natalie Nokoff; Blake Palmer; Alethea Paradis; Dix Poppas; Brian VanderBrink; Kristy J Scott Reyes; Amy Tishelman; Cortney Wolfe-Christensen; Elizabeth Yerkes; Larry L Mullins; Laurence Baskin
Journal:  J Pediatr Urol       Date:  2020-06-01       Impact factor: 1.921

  2 in total

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