Hypertension detection, management, control and associated factors among residents accessing community health services in Beijing.

The aim of this study was to analyse high blood pressure detection, management, control and associated factors among residents accessing community health services (CHSs) in Beijing. We screened for HBP in 9524 individuals aged 50 years or older who accessed care in four Beijing CHSs. Among the 9397 residents with questionnaire responses that qualified them for inclusion in the study, 5029 patients with HBP were identified, 1510 (i.e., 30% of the HBP patient group) of whom were newly identified cases. The rate of hypertension detection was 53.5%. Among the 5029 HBP patients, the rates of awareness, treatment and control of hypertension were 70.0%, 62.1% and 29.6%, respectively. In general, the rate of hypertension control was higher when the rates of hypertension awareness and treatment were higher in subgroups stratified by different sociodemographic and risk factors, except for the overweight and obesity subgroups. In conclusion, suboptimal HBP awareness, treatment, and control are still major problems confronting CHSs in Beijing. Control of hypertension in the population may be improved by increasing awareness and improving the treatment of hypertension in CHSs.

Hypertension is the most important modifiable risk factor for cardio-cerebrovascular diseases. In 2010, high blood pressure (HBP) accounted for 12.0% of disability-adjusted life-years and 24.6% of deaths in China and, after a composite of dietary risk factors, was the second most important risk factor for total disease burden1. Thus, achieving optimal blood pressure (BP) control in patients with HBP is an important objective for the early prevention and control of cardio-cerebrovascular diseases and for decreasing disease burden in China. Epidemiological surveys have shown that the prevalence of hypertension in China has increased from 13.6% in 1991 to 18.8% in 2002, whereas the rates of antihypertensive treatment and control are lower than those in developed countries2345678910111213. As part of the healthcare reforms in China, there has been an increasing focus on hypertension prevention and control in community health services (CHSs). Following the release and implementation of Chinese guidelines for the management of hypertension, all CHS centres or stations in Beijing, covering both urban and rural communities, have been involved in the management of hypertension since 200814151617. These measures have improved the management and control of BP in patients with HBP in the community. However, it is unclear how the measures have affected current detection and management of hypertension in Beijing community residents. One of the main measures of the primary prevention of cardio-cerebrovascular diseases is increasing awareness and treatment of patients with hypertension, thereby achieving optimal BP control. However, there is little information on the factors associated with Hypertension detection, awareness, treatment and control in the Chinese CHS. Therefore, the aim of this study was to improve the prevention and control of HBP in the population by analysing HBP detection, management, control and associated factors in individuals utilising the CHS in Beijing. The study used baseline data from the “Trial on community-based screening and intervention technologies for individuals at high risk of stroke” in “Research on appropriate technologies for community-based stroke prevention and control” granted by the National Key Technology R&D Program during the eleventh “Five-year” plan.

Results

Characteristics of the participants

There were 9397 participants (mean age 60.2 ± 7.9 years, 34.8% men) whose questionnaires qualified them for inclusion in this study. The mean SBP and DBP were 129.9 ± 17.9 and 78.3 ± 10.1 mm Hg, respectively. The distributions of SBP and DBP according to age and gender are shown in Figure 1. Significant differences between men and women were found with respect to age, education, marriage, occupation, workload, BMI, smoking, drinking, diabetes, hyperlipidaemia and family history of hypertension, but not with respect to ethnicity or heart disease (table 1).

Figure 1

Distributions of systolic blood pressure and diastolic blood pressure according to participants' age and gender.

Table 1

Characteristics of the participants

	Total (n = 9397)		Men (n = 3274)		Women (n = 6123)
Variables	N	Col%	N	Col%	N	Col%	P value
Age group (year)
50–54	2836	30.2%	784	23.9%	2052	33.5%	<0.001
55–64	3766	40.1%	1420	43.4%	2346	38.3%
65–	2795	27.9%	1070	32.7%	1725	28.2%
Ethnicity
Han	9027	96.1%	3149	96.2%	5878	96.0%	0.663
Other	370	3.9%	125	3.8%	245	4.0%
Education
High school	1475	15.7%	747	22.8%	728	11.9%	<0.001
Senior middle school	2787	29.7%	907	27.7%	1880	30.7%
Junior middle school	3624	38.6%	1288	39.3%	2336	38.2%
Primary school	1048	11.2%	290	8.9%	758	12.4%
illiterate	463	4.9%	42	1.3%	421	6.9%
Marriage
Married	8585	91.4%	3149	96.2%	5436	88.8%	<0.001
Divorced/widowed/single	812	8.6%	125	3.8%	687	11.2%
Occupation
Employed	1914	20.4%	1077	32.9%	837	13.7%	<0.001
Housebound	284	3.0%	21	0.6%	263	4.3%
Retired	7199	76.6%	2176	66.5%	5023	82.0%
Workload
Light	1177	12.5%	430	13.1%	747	12.2%	<0.001
Mild	6062	64.5%	1983	60.6%	4079	66.6%
Moderate	1896	20.2%	730	22.3%	1166	19.0%
Heavy	262	2.8%	131	4.0%	131	2.1%
Overweight/obesity
BMI < 24	3086	32.8%	1000	30.5%	2086	34.1%	<0.001
24 ≤ BMI < 28	4205	44.7%	1582	48.3%	2623	42.8%
BMI ≥ 28	2106	22.4%	692	21.1%	1414	23.1%
Smoking
Regular smoking	1713	18.2%	1422	43.4%	291	4.8%	<0.001
Occasional smoking	276	2.9%	170	5.2%	106	1.7%
Quit smoking	662	7.0%	567	17.3%	95	1.6%
Never smoked	6746	71.8%	1115	34.1%	5631	92.0%
Drinking
Regular drinking	1121	11.9%	1017	31.1%	104	1.7%	<0.001
Occasional drinking	1912	20.3%	1116	34.1%	796	13.0%
Quit drinking	141	1.5%	126	3.8%	15	0.2%
Never drank	6223	66.2%	1015	31.0%	5208	85.1%
Family history of hypertension
Yes	5488	58.4%	1798	54.9%	3690	60.3%	<0.001
No	192	2.0%	66	2.0%	126	2.1%
Unknown	3717	39.6%	1410	43.1%	2307	37.7%
Co-morbidities
Heart diseases
Yes	1659	17.7%	551	16.8%	1108	18.1%	0.262
No	7097	75.5%	2504	76.5%	4593	75.0%
Unknown	641	6.8%	219	6.7%	422	6.9%
Diabetes
Yes	1287	13.7%	467	14.3%	820	13.4%	0.001
No	7613	81.0%	2599	79.4%	5014	81.9%
Unknown	497	5.3%	208	6.4%	289	4.7%
Hyperlipidaemia
Yes	2371	25.2%	773	23.6%	1598	26.1%	0.007
No	5262	56.0%	1844	56.3%	3418	55.8%
Unknown	1764	18.8%	657	20.1%	1107	18.1%

Hypertension detection, awareness, treatment and control

Of the 9397 residents whose questionnaires qualified them for inclusion in this study, 5029 HBP patients were identified, 1510 (30%) of which were new cases, i.e., were first identified in this investigation. The detection rate of hypertension in this community population was 53.5%. Among the 5029 HBP patients, the rates of awareness, treatment and control (SBP < 140 mm Hg and DBP < 90 mm Hg) were 70.0%, 62.1% and 29.6%, respectively. The mean age of the 5029 HBP patients was 61.7 ± 8.1 years and 38.1% were men. The detection rate of hypertension; the percentages of HBP patients who were aware, treated, and controlled; and the percentage of treated hypertensive persons who were controlled were different across the different target individuals (table 2).

Table 2

Detection rates of hypertension, percentages of HBP patients who were aware, treated and controlled and percentages of treated hypertensive patients who were controlled in different target groups

Variables	detection Rate(95%CI)*	hypertensive aware(95%CI)#	hypertensive treated(95%CI)#	hypertensive controlled(95%CI)†	hypertensive, treated, Controlled(95%CI)§
Age group (year)
50–54	41.9%(40.1%–43.7%)	64.6%(61.9%–67.3%)	55.2%(52.4%–58.0%)	25.4%(22.9%–27.9%)	41.5%(37.7%–45.2%)
55–64	52.0%(50.4%–53.6%)	70.0%(68.0%–72.0%)	61.8%(59.6%–64.0%)	31.7%(29.6%–33.8%)	47.4%(44.5%–50.2%)
65–	67.3%(65.6%–69.1%)	73.4%(71.4%–75.4%)	66.8%(64.7%–68.9%)	30.2%(28.1%–32.3%)	43.1%(40.3%–45.8%)
Gender
Men	58.5%(56.8%–60.2%)	64.7%(62.6%–66.8%)	55.6%(53.4%–57.8%)	23.8%(21.9%–25.7%)	39.1%(36.2%–42.0%)
women	50.8%(49.6%–52.1%)	73.2%(71.6%–74.8%)	66.1%(64.4%–67.8%)	33.2%(31.5%–34.9%)	47.1%(45.0%–49.3%)
Ethnicity
Han	53.4%(52.3%–54.4%)	70.2%(68.9%–71.5%)	62.3%(60.9%–63.7%)	29.6%(28.3%–30.9%)	44.2%(42.4%–45.9%)
Other	57.3%(52.3%–62.3%)	65.6%(59.2%–72.0%)	57.1%(50.4%–63.8%)	29.7%(23.5%–35.9%)	50.4%(41.5%–59.3%)
Education
High school	49.8%(47.3%–52.4%)	72.5%(69.3%–75.7%)	65.0%(61.6%–68.4%)	36.1%(32.6%–39.6%)	52.1%(47.6%–56.6%)
Senior middle school	47.3%(45.4%–49.1%)	68.2%(65.7%–70.7%)	61.3%(58.7%–63.9%)	29.3%(26.8%–31.8%)	44.5%(41.1%–47.9%)
Junior middle school	54.2%(52.6%–55.8%)	68.8%(66.8%–70.8%)	60.2%(58.0%–62.4%)	28.1%(26.1%–30.1%)	43.0%(40.2%–45.8%)
Primary school	65.3%(62.4%–68.1%)	74.1%(70.8%–77.4%)	65.9%(62.3%–69.5%)	30.7%(27.2%–34.2%)	43.9%(39.3%–48.5%)
illiterate	70.8%(66.7%–75.0%)	69.8%(64.8%–74.8%)	62.5%(57.3%–67.7%)	23.2%(18.6%–27.8%)	35.1%(28.6%–41.7%)
Marriage
Married	52.4%(51.3%–53.5%)	69.7%(68.4%–71.0%)	61.7%(60.3%–63.1%)	29.8%(28.5%–31.1%)	45.0%(43.2%–46.9%)
Divorced/widowed/single	65.4%(62.1%–68.7%)	72.3%(68.5%–76.1%)	65.3%(61.3%–69.3%)	27.9%(24.1%–31.7%)	39.2%(34.1%–44.3%)
Occupation
Employed	50.2%(48.0%–52.4%)	66.6%(63.6%–69.6%)	57.6%(54.5%–60.7%)	26.7%(23.9%–29.5%)	42.8%(38.7%–46.9%)
Housebound	54.6%(48.8%–60.4%)	72.3%(65.3%–79.3%)	60.0%(52.3%–67.7%)	26.5%(19.6%–33.4%)	38.7%(28.8%–48.6%)
Retired	54.4%(53.2%–55.5%)	70.7%(69.3%–72.1%)	63.3%(61.8%–64.8%)	30.5%(29.1%–31.9%)	45.0%(43.0%–46.9%)
Workload
Light	53.9%(51.0%–56.7%)	70.0%(66.4%–73.6%)	62.9%(59.1%–66.7%)	29.8%(26.2%–33.4%)	45.4%(40.5%–50.2%)
Mild	53.1%(51.9%–54.4%)	70.4%(68.8%–72.0%)	62.7%(61.0%–64.4%)	29.9%(28.3%–31.5%)	44.4%(42.2%–46.5%)
Moderate	53.1%(50.9%–55.4%)	69.1%(66.2%–72.0%)	60.5%(57.5%–63.5%)	29.1%(26.3%–31.9%)	43.5%(39.6%–47.5%)
Heavy	64.1%(58.3%–69.9%)	66.1%(58.9%–73.3%)	57.7%(50.2%–65.2%)	27.4%(20.7%–34.1%)	46.4%(36.5%–56.3%)
Overweight/obesity
BMI < 24	40.9%(39.2%–42.6%)	64.2%(61.6%–66.8%)	56.8%(54.1%–59.5%)	29.0%(26.5%–31.5%)	47.4%(43.8%–51.1%)
24 ≤ BMI < 28	54.9%(53.4%–56.4%)	70.1%(68.2%–72.0%)	61.7%(59.7%–63.7%)	30.5%(28.6%–32.4%)	45.8%(43.2%–48.4%)
BMI ≥ 28	69.3%(67.3%–71.2%)	74.8%(72.6%–77.0%)	67.3%(64.9%–69.7%)	28.8%(26.5%–31.1%)	40.1%(37.1%–43.2%)
Smoking
Regular smoking	54.1%(51.7%–56.4%)	61.3%(58.2%–64.4%)	52.3%(49.1%–55.5%)	23.3%(20.6%–26.0%)	40.3%(35.9%–44.7%)
Occasional smoking	56.9%(51.0%–62.7%)	69.4%(62.2%–76.6%)	58.0%(50.3%–65.7%)	28.0%(21.0%–35.0%)	45.1%(34.8%–55.3%)
Quit smoking	66.8%(63.2%–70.4%)	71.0%(66.8%–75.2%)	63.6%(59.1%–68.1%)	25.6%(21.5%–29.7%)	37.0%(31.4%–42.7%)
Never smoked	51.9%(50.7%–53.1%)	72.1%(70.6%–73.6%)	64.7%(63.1%–66.3%)	31.9%(30.4%–33.4%)	46.2%(44.1%–48.2%)
Drinking
Regular drinking	60.9%(58.1%–63.8%)	61.9%(58.3%–65.5%)	51.7%(48.0%–55.4%)	20.2%(17.2%–23.2%)	35.4%(30.4%–40.4%)
Occasional drinking	51.6%(49.4%–53.9%)	65.3%(62.3%–68.3%)	56.2%(53.1%–59.3%)	27.7%(24.9%–30.5%)	44.5%(40.4%–48.6%)
Quit drinking	63.1%(55.2%–71.1%)	76.4%(67.6%–85.2%)	68.5%(58.8%–78.2%)	42.7%(32.4%–53.0%)	54.1%(41.6%–66.6%)
Never drank	51.5%(50.3%–52.8%)	72.9%(71.4%–74.4%)	65.9%(64.3%–67.5%)	31.8%(30.2%–33.4%)	45.6%(43.5%–47.7%)
Family history of hypertension
Yes	59.6%(58.3%–60.9%)	76.9%(75.4%–78.3%)	69.2%(67.6%–70.8%)	32.9%(31.3%–34.6%)	44.5%(42.5%–46.6%)
No	49.5%(42.4%–56.6%)	51.6%(41.5%–61.6%)	46.3%(36.3%–56.3%)	20.0%(12.0%–28.0%)	43.2%(28.5%–57.8%)
Unknown	44.7%(43.1%–46.3%)	57.5%(55.1%–59.8%)	49.0%(46.6%–51.4%)	23.6%(21.6%–25.7%)	44.0%(40.6%–47.5%)
Co-morbidities
Heart diseases
Yes	69.9%(67.7%–72.1%)	85.6%(83.6%–87.6%)	79.1%(76.8%–81.4%)	38.4%(35.6%–41.2%)	45.5%(42.3%–48.8%)
No	49.4%(48.2%–50.5%)	65.0%(63.4%–66.6%)	57.0%(55.4%–58.6%)	27.1%(25.6%–28.6%)	44.4%(42.2%–46.6%)
Unknown	56.9%(53.1%–60.8%)	67.9%(63.1%–72.7%)	56.7%(51.6%–61.8%)	25.8%(21.3%–30.3%)	39.6%(33.0%–46.3%)
Diabetes
Yes	66.9%(64.3%–69.5%)	80.0%(77.3%–82.7%)	75.3%(72.4%–78.2%)	36.0%(32.8%–39.2%)	45.8%(41.9%–49.7%)
No	51.3%(50.2%–52.4%)	68.6%(67.1%–70.1%)	60.8%(59.3%–62.3%)	28.8%(27.4%–30.2%)	44.3%(42.3%–46.3%)
Unknown	52.9%(48.5%–57.3%)	57.8%(51.8%–63.8%)	43.7%(37.7%–49.7%)	20.5%(15.6%–25.4%)	39.1%(30.2%–48.1%)
Hyperlipidaemia
Yes	63.1%(61.1%–65.0%)	81.5%(79.5%–83.5%)	74.6%(72.4%–76.8%)	38.3%(35.8%–40.8%)	48.7%(45.8%–51.7%)
No	48.8%(47.5%–50.2%)	65.6%(63.8%–67.4%)	58.7%(56.8%–60.6%)	27.6%(25.9%–29.3%)	44.2%(41.7%–46.7%)
Unknown	54.7%(52.4%–57.0%)	63.8%(60.8%–66.8%)	51.8%(48.6%–55.0%)	21.7%(19.1%–24.3%)	35.4%(31.2%–39.6%)
Total	53.5%(52.5%–54.5%)	70.0%(68.7%–71.2%)	62.1%(60.8%–63.5%)	29.6%(28.4%–30.9%)	44.4%(42.7%–46.1%)

*SBP ≥ 140 mm Hg and/or DBP ≥ 90 mm Hg and/or taking antihypertensive medication in the recent two weeks among participants.

#Among patients with hypertension.

†The proportion of patients with SBP < 140 mm Hg and DBP < 90 mm Hg among patients with hypertension.

§The proportion of patients on an antihypertensive medication with systolic BP < 140 mm Hg and diastolic BP < 90 mm Hg.

Sociodemographic characteristics and factors associated with detection, awareness, treatment and control

Figure 2 shows the adjusted odds ratios and 95% confidence intervals for hypertension detection, awareness, treatment and control in different target groups.

Figure 2

Adjusted* odds ratios and 95% confidence intervals for hypertension detection, awareness, treatment and control in different target groups.

*adjusted other different factors including age, gender, ethnicity, education, marriage, occupation, workload, BMI, smoking, drinking, heart disease, diabetes, hyperlipidaemia.

Older age was associated with higher rates of hypertension detection, awareness, treatment and control.

Men had a higher rate of hypertension detection but lower rates of hypertension awareness, treatment and control than women.

No difference was found in the rates of hypertension detection, awareness, treatment and control between the Han and other ethnicities, between married and divorced/widowed/single patients or between employed and retired/housebound patients.

A higher level of education was associated with a lower rate of hypertension detection but a higher rate of hypertension control compared with lower level of education.

Light, mild and moderate workloads were associated with lower rates of hypertension detection than heavy workloads.

Overweight and obesity were associated with higher rates of hypertension detection, awareness and treatment but lower rates of hypertension control than low/normal weight.

Patients who had stopped smoking had higher rates of hypertension detection and treatment compared with regular smokers whereas patients who had never smoked only had a higher rate of hypertension detection.

Patients who were occasional drinkers or never drank had a lower rate of hypertension detection compared with patients who regularly drank. In contrast, patients who never drank had a higher rate of hypertension treatment than other drinkers, and patients who had stopped drinking had a higher rate of hypertension control than the other categories of drinkers.

Patients with a family history of hypertension had higher rates of hypertension detection, awareness, treatment and control compared with patients with no or an unknown family history of hypertension. Similar associations were found in patients with heart diseases, diabetes and hyperlipidaemia.

Adherence to drug use and control

The rate of BP control was 45.8% in HBP patients with regular therapy,32.2% in HBP patients with irregular therapy and 3.2% in HBP patients without therapy. In a comparison of HBP patients with regular therapy using a multivariate model, the adjusted OR of BP control was 0.587 (95%CI: 0.476–0.725) in HBP patients with irregular therapy and 0.041 (95%CI: 0.031–0.054) in HBP patients without therapy.

Discussion

The present study indicates that suboptimal HBP awareness, treatment and control in the population are still major problems in the current CHS in Beijing. More than half of the subjects aged 50 years or older had hypertension (53.5%), and 30% of all the HBP patients were newly identified in this study. Of the 5029 HBP patients identified, the proportion who regularly used antihypertensive drugs was 55.4%, whereas the overall rate of hypertension control was 29.6%. When the 1510 new cases were excluded, the proportion of HBP patients who regularly used antihypertensive drugs was 79.3%, whereas the overall rate of optimal BP control was 44.4%. Because the rate of new cases of HBP patients identified decreased with increasing age in our study, if the current CHS program included younger residents in the community, it is likely that the rate of new HBP patients identified among younger residents would be higher than the 30% identified in the present study among elder residents aged 50 years or older. The rates of HBP awareness, treatment and control among HBP patients in our investigation were 70.0%, 62.1% and 29.6%, respectively. These rates were higher than the HBP awareness, treatment and control rates of 30.2%, 24.7% and 6.1%, respectively, found in the 2002 China national survey2 and those found in other studies in China345678920 and in other developing countries2122, but they were lower than the respective rates of 80.6%, 71.6% and 48.4% in the 2007 to 2008 US National Health and Nutrition Examination Survey13. However, there was no similarity in age, sampling and representativeness between the studies.

In the present study, the non-modifiable sociodemographic and risk factors associated with hypertension detection, awareness, treatment and control included age, gender, education, workload and family history of hypertension but not ethnicity, marriage or occupation.

In the multivariate analysis, we found that old age was independently associated with higher hypertension awareness, treatment and control; this result is consistent with the results of other studies212324.

In this study, men had a higher rate of hypertension detection than women, but they exhibited lower rates of awareness, treatment and control. It is commonly observed both in developed2526 and developing2324 countries, that the rates of hypertension awareness, treatment and control are higher in women than in men. In contrast, women aged 50 years or older had a higher prevalence of hypertension than men in Zhejiang, China, possibly due to menopause23. Compared with women, men visit physicians less often, have shorter consultations, and tend to see their physicians later in the course of their illness. which may be the reason why women have higher hypertension awareness, treatment and control than men.

Age and gender are not modifiable risk factors of HBP; however, due to their social roles in the community, women and the elderly are not neglected with respect to health education and health promotion for the prevention and control of HBP27.

A higher education level was associated with a lower rate of hypertension detection and an increase in optimal BP control in community HBP patients. Compared with people who have attained a high level of education, people with a lower education level usually have less knowledge about hypertension and consequently live an unhealthier lifestyle. In previous studies232829, a lower education level was associated with poor BP control, which was consistent with the findings of the present study.

As one of the main factors analysed in this study, a family history of hypertension was positively associated with rates of hypertension detection, awareness, treatment and control in our investigation. A family history of hypertension was found to be associated with hypertension among the elderly in Costa Rican30. Optimal BP control was also most likely due to better awareness and treatment of hypertension in HBP patients with a family history of hypertension.

Few studies have documented associations between workload and HBP detection, awareness, treatment and control. In this study, participants with Light, mild and moderate workloads had lower rates of hypertension detection compared with participants with heavy workloads.

Ethnicity, marriage and occupation did not show significant effects on hypertension detection, awareness, treatment and control in the multivariate logistic regression analyses. However, the non-significance of the results does not necessarily mean that the relationship does not exist; it is possible that the sample sizes in some subgroups did not have sufficient power to detect some relationships. For example, with regard to ethnicity, although no significant differences in hypertension detection, awareness, treatment and control between Han and other Chinese ethnicities were found in our study, other studies have documented ethnic differences in the rates of treatment and control313233. Cummings et al found that the probability of African Americans having a BP below the target value of 130/80 mm Hg was 39% lower than the corresponding probability for European Americans in multivariate-adjusted models (<130/80 mm Hg in African Americans vs. European Americans: 30 vs. 43%)31.

In the present study, we found that the modifiable risk factors associated with HBP included Smoking; drinking; overweight or obesity due to physical inactivity; and a history of heart diseases, diabetes or hyperlipidaemia. However, the associations of smoking and drinking with hypertension detection, awareness, treatment and control were unclear. In our investigation, there were no associations between cigarette smoking and hypertension awareness and control in HBP patients, whereas the rate of hypertension detection in participants who had never smoked or had stopped smoking was higher than that in participants who regularly smoked and the rate of treatment of hypertension in HBP patients who had stopped smoking was higher than that in HBP patients who regularly smoked. Indeed, HBP patients who had stopped smoking were more likely to receive hypertension treatment. In Muntner's study, controlled hypertension was more common among individuals who underwent lifestyle modification34. Interestingly, on the contrary, non-smoking women were more likely to have uncontrolled high blood pressure than their smoking counterparts in the Oslo Health Study 2000–200135. In our study, we found that the rate of hypertension detection in participants who never or only occasionally drank was lower than that in participants who regularly drank; furthermore, participants who never drank were more likely to receive hypertension treatment, and HBP patients who had stopped drinking were more likely to have their hypertension under control. Previous studies confirmed our findings that patients who regularly drank had a higher rate of HBP detection compared with those patients who never drank whereas there were no differences between these patients groups with respect to the rates of awareness, treatment and control2324.

Generally, the rate of hypertension control was higher when the rates of hypertension awareness and treatment were higher. However, our findings showed that overweight and obese people were more likely to be aware of, and treated for, hypertension but had poorer BP control compared with people with normal/low body weight. Other studies have also shown that overweight or obesity was significantly associated with hypertension and better BP awareness but poorer BP control among hypertensive patients2336. It has been suggested that overweight and obesity positively influence BP monitoring and the prescription of medication for treatment; thus resulting in higher rates of awareness and treatment. In contrast, overweight or obese patients were less likely to have their BP adequately controlled compared with low/normal weight patients despite their higher awareness and treatment rates. In Czernichow's opinion, poorer BP control in obese HBP patients may have been a consequence of obesity and its complex pathophysiology rather than a consequence of inadequate therapeutic decisions made by clinicians36.

Optimal BP control in HBP patients with co-morbidities is more difficult than that in HBP patients without co-morbidities; however, optimal BP control rates in HBP patients with co-morbidities were seemingly higher than those in HBP patients without co-morbidities in the CHS. Similarly, awareness of known heart diseases, diabetes and hyperlipidaemia was associated with a higher probability of awareness, treatment and control of HBP. The rates of unknown histories of hyperlipidaemia, heart diseases and diabetes among the 5029 HBP patients investigated were 19.2%, 7.3% and 5.2%, respectively; the rates of optimal BP control in these groups of HBP patients were lower than those in the group of HBP patients with clear (yes or no) histories of diseases, implying that awareness of co-morbidities is important for facilitating optimal BP control in community HBP patients. Similar findings were observed in the Oslo Health Study 2000–2001, and the presence of cardiovascular disease or diabetes and the prescription of cholesterol-lowering statins were independently associated with better control of BP35.

The potential reasons for inadequate BP control are numerous and include not only insufficient patient knowledge but also biological resistance, patient lifestyle/behavioural choices, comorbid conditions and treatments, non-adherence to medication, inadequate access to health care, discrimination by race and gender, failure to adopt BP guidelines and lack of treatment intensification3137. Asides from these sociodemographic and risk factors, drug adherence is also an important factor for optimal BP control. Joshi et al observed that drug non-compliance may help explain poor BP control in patients undergoing treatment for hypertension38. Bosworth et al. found that African Americans in the Veterans Administration system were 81% more likely than European Americans to be nonadherent to medications for BP control38. Safford et al found that African American hypertensive subjects were more likely to have a more intense antihypertensive regimen than European Americans across all age and income groups but were still more likely to have elevated blood pressure values, suggesting the presence of medication nonadherence and/or treatment resistance39. We also observed that BP control in patients who regularly use their antihypertensive drugs was better than that in patients who Intermittently/occasionally use antihypertensive drugs. In addition, only approximately 60% of HBP patients who were investigated regularly took their antihypertensive medicine, implying that gaps in drug compliance could also be improved.

Unlike previous observational studies, this was a community-based study that screened individuals at high risk for stroke and included hypertension detection. The present study has limitations, including its cross-sectional design; the use of self-reported disease and medication adherence measures; limited study factors for exploring associations with HBP detection, awareness, treatment and optimal control; and the use of an identical BP control target for HBP patients with co-morbidities and elderly HBP patients. We were unable to collect information on the type of and compliance with antihypertensive therapy and to identify secondary and/or resistant hypertension in HBP patients. In addition, as only a quarter of the individuals in the communities participated in our investigation and there were different responses between subgroups (e.g., gender), our results could be overestimated or underestimated. However, our findings suggest that the detection, treatment/management and control of hypertension can be further improved.

In conclusion, suboptimal HBP awareness, treatment and control are still major problems associated with the current CHS in Beijing. The associations of HBP awareness, treatment and control with most sociodemographic and risk factors indicate that the control of hypertension in populations can be improved by increased awareness and treatment of hypertension in the course of CHS care. However, the mechanisms of some sociodemographic and risk factors associated with the inconsistency between hypertension awareness, treatment and control in different subgroups of patients should be further expected in future studies.

Methods

Subjects

Using a quasi-experimental community trial design, 4 communities with a total population of approximately 100,000 people, who received care at 4 Beijing CHS Centres (or Stations), were defined. These centres were the Yongwai CHS Centre and the Tiyuguanlu CHS Centre in the Dongcheng (previously Chongwen) District, as well as the Pingguoyuan CHS Centre and the Xihuangcun CHS Station affiliated with the Capital Steel Hospital in the Shijingshan District. A total of 37626 individuals aged 50 years or older were identified and accounted for 41.14% of the 91453 residents in the defined communities. Patients with stroke or residents who refused to participate were excluded from the study. A total of 9524 individuals aged 50 years or older participated in the study for identifying individuals at high risk of stroke, accounting for 25.3% of the 37626 targeted residents. A total of 9397 individuals had questionnaire responses that qualified them for inclusion in the analysis.

Ethics statement

This study was approved by the Ethics Committee of the Beijing Tiantan Hospital affiliated with the Capital Medical University, shared by the Beijing Neurosurgical Institute, and written informed consent was obtained from all participants. The study was performed in accordance with approved guidelines.

Survey method and content

Face-to-face interviews and physical examinations were performed on subjects according to the questionnaire used in the selected CHS centres between May and December in 2008; the questionnaire was designed by medical and research staff from the Beijing Neurosurgical Institute. The survey content included questions regarding age; gender; race; education; marriage; occupation; workload; smoking; drinking; family history of hypertension; histories of hypertension, heart disease, diabetes mellitus and dyslipidemia; and BP, height and weight measurements and Cerebral Vascular Hemodynamic Index (CVHI) derived from physical examination18.

Workload was classified into light, mild, moderate and severe levels according to the daily work activities as follows: light covering sedentary work (e.g., reading, writing, performing office work and assembling and repairing watches and radios) that does not require strenuous muscle activity; mild covering standing work that can include walking, or sedentary work requiring no intense muscle activity (e.g., teaching, conducting laboratory work, typing, operating a computer and performing sales assistant duties); moderate covering work that requires more intense muscle activity (e.g., performing the daily activities of students, driving a vehicle, or performing electrical installation, metal cutting or woodworking); and severe covering occupations such as steelmaking, lathe operation, dancing and sports. Smoking was categorised as regular smoking (i.e. more than one cigarette per day for more than 6 months), occasional smoking, quit smoking (had not smoked for more than 6 months) and never smoked. Similarly, drinking was divided into regular drinking (≥once a week), occasional drinking, quit drinking (had not had an alcoholic drink for more than 6 months) and never drank.

Hypertension was defined as having a history of hypertension, or taking antihypertensive medication in the recent 2 weeks, having a systolic blood pressure (SBP) ≥ 140 mm Hg or having a diastolic blood pressure (DBP) ≥ 90 mm Hg. The use of antihypertensive drugs in the past year (i.e., adherence to medication) was divided into regular use (more than 9 months during the past year), intermittent use (more than 6 months in the past year), occasional use (less than 6 months in the past year) and never used. The heart diseases inquiries included coronary heart disease, hypertensive heart disease, rheumatic heart disease and atrial fibrillation. Histories of heart disease, diabetes and hyperlipidaemia were categorised as yes, no or unknown according to the patients' self-reports.

BP was measured twice in the right arm in the seated position with a mercury sphygmomanometer after the participant had been seated for 5 minutes. The average of the two readings was used in the analysis. Weight was measured to the nearest 0.1 Kg using weight scales with participants wearing light clothing without shoes. Height was measured to the nearest 0.1 cm using a stadiometer with shoes removed. Body mass index (BMI) was calculated as weight (kg) divided by height squared (m2). Overweight and obesity were defined as 24 ≤ BMI<28 and BMI ≥ 28, respectively, according to the recommended standard Chinese thresholds for overweight and obesity19. Data on CVHI evaluation were not used in this study, and were therefore omitted from the analysis.

Statistical analysis

The detection rate of hypertension in the community population was the rate of the detected community patients with hypertension among the community residents who were actually screened. New cases were defined as HBP patients who were first identified in this study. The rates of hypertension awareness, treatment and control were the percentages of HBP patients who were aware, treated and controlled (i.e., SBP < 140 mm Hg and DBP < 90 mm Hg), respectively, among all HBP patients detected in the community. The control rate of treated hypertensive patients was the rate of HBP patients with SBP < 140 mm Hg and DBP < 90 mm Hg among all HBP patients in the community who had been treated in the past two weeks.

The characteristics of male vs. female subjects were compared by using the chi square test. The rates of hypertension detection, awareness, treatment and control in the subgroups of different factors were calculated and compared by non-conditional binary logistic regression after adjusting for different factors including age group, gender, ethnicity, education, marriage, occupation, workload, BMI, smoking, drinking, family history of hypertension, heart disease, diabetes and hyperlipidaemia in a multivariate model. Given the relationship between HBP control and drug adherence, the association between antihypertensive treatment in the past year and control was further analysed by introducing the antihypertensive treatment into the multivariate model. All statistical calculations were performed using SPSS 13.0 software (SPSS Inc. Chicago, IL, USA). P < 0.05 was considered statistically significant.

Author Contributions

B.J., H.L., X.R. and H.Z. carried out the field works, data collection and analysis. B.J., S.W. and W.W. designed the study and directed its implementation. B.J. performed the statistical analysis and manuscript writing. All contributors discussed the findings and approved the final version for publication.