Literature DB >> 24783957

Alveolar epithelium: beyond the barrier.

Zea Borok1.   

Abstract

I am deeply honored to have been awarded an American Thoracic Society Recognition Award for Scientific Accomplishment for 2014. Over the last 20 years, it has become clear that the alveolar epithelium, my area of research focus, is not simply a gas exchange surface and barrier to leakage of fluid and protein into the alveoli, but is an active participant in the pathogenesis of a number of lung diseases, including pulmonary fibrosis. Recognition by this Award stimulates a review of the awardee's contributions to the field, as summarized in this perspective.

Entities:  

Mesh:

Year:  2014        PMID: 24783957      PMCID: PMC4068954          DOI: 10.1165/rcmb.2014-0089PS

Source DB:  PubMed          Journal:  Am J Respir Cell Mol Biol        ISSN: 1044-1549            Impact factor:   6.914


  54 in total

1.  Type I alveolar epithelial phenotype in primary culture.

Authors:  Shaohua Wang; Rolf D Hubmayr
Journal:  Am J Respir Cell Mol Biol       Date:  2010-07-08       Impact factor: 6.914

2.  Endoplasmic reticulum stress enhances fibrotic remodeling in the lungs.

Authors:  William E Lawson; Dong-Sheng Cheng; Amber L Degryse; Harikrishna Tanjore; Vasiliy V Polosukhin; Xiaochuan C Xu; Dawn C Newcomb; Brittany R Jones; Juan Roldan; Kirk B Lane; Edward E Morrisey; Michael F Beers; Fiona E Yull; Timothy S Blackwell
Journal:  Proc Natl Acad Sci U S A       Date:  2011-06-13       Impact factor: 11.205

3.  Ligand-independent transforming growth factor-β type I receptor signalling mediates type I collagen-induced epithelial-mesenchymal transition.

Authors:  Lucas DeMaio; Stephen T Buckley; Manda S Krishnaveni; Per Flodby; Mickael Dubourd; Agnes Banfalvi; Yiming Xing; Carsten Ehrhardt; Parviz Minoo; Beiyun Zhou; Edward D Crandall; Zea Borok
Journal:  J Pathol       Date:  2011-12-09       Impact factor: 7.996

4.  TGFβ signaling in lung epithelium regulates bleomycin-induced alveolar injury and fibroblast recruitment.

Authors:  Amber L Degryse; Harikrishna Tanjore; Xiaochuan C Xu; Vasiliy V Polosukhin; Brittany R Jones; Chad S Boomershine; Camila Ortiz; Taylor P Sherrill; Frank B McMahon; Linda A Gleaves; Timothy S Blackwell; William E Lawson
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2011-03-25       Impact factor: 5.464

5.  Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition.

Authors:  Jason R Rock; Christina E Barkauskas; Michael J Cronce; Yan Xue; Jeffrey R Harris; Jiurong Liang; Paul W Noble; Brigid L M Hogan
Journal:  Proc Natl Acad Sci U S A       Date:  2011-11-28       Impact factor: 11.205

6.  Role of endoplasmic reticulum stress in epithelial-mesenchymal transition of alveolar epithelial cells: effects of misfolded surfactant protein.

Authors:  Qian Zhong; Beiyun Zhou; David K Ann; Parviz Minoo; Yixin Liu; Agnes Banfalvi; Manda S Krishnaveni; Mickael Dubourd; Lucas Demaio; Brigham C Willis; Kwang-Jin Kim; Roland M duBois; Edward D Crandall; Michael F Beers; Zea Borok
Journal:  Am J Respir Cell Mol Biol       Date:  2010-12-17       Impact factor: 6.914

7.  Epithelium-specific deletion of TGF-β receptor type II protects mice from bleomycin-induced pulmonary fibrosis.

Authors:  Min Li; Manda Sai Krishnaveni; Changgong Li; Beiyun Zhou; Yiming Xing; Agnes Banfalvi; Aimin Li; Vincent Lombardi; Omid Akbari; Zea Borok; Parviz Minoo
Journal:  J Clin Invest       Date:  2010-12-06       Impact factor: 14.808

8.  Differential regulation of rat aquaporin-5 promoter/enhancer activities in lung and salivary epithelial cells.

Authors:  Z Borok; X Li; V F Fernandes; B Zhou; D K Ann; E D Crandall
Journal:  J Biol Chem       Date:  2000-08-25       Impact factor: 5.157

9.  Inhibition of Wnt/beta-catenin/CREB binding protein (CBP) signaling reverses pulmonary fibrosis.

Authors:  William R Henderson; Emil Y Chi; Xin Ye; Cu Nguyen; Ying-tzang Tien; Beiyun Zhou; Zea Borok; Darryl A Knight; Michael Kahn
Journal:  Proc Natl Acad Sci U S A       Date:  2010-07-21       Impact factor: 11.205

10.  SNAI transcription factors mediate epithelial-mesenchymal transition in lung fibrosis.

Authors:  A Jayachandran; M Königshoff; H Yu; E Rupniewska; M Hecker; W Klepetko; W Seeger; O Eickelberg
Journal:  Thorax       Date:  2009-10-22       Impact factor: 9.139

View more
  8 in total

Review 1.  When Is an Alveolar Type 2 Cell an Alveolar Type 2 Cell? A Conundrum for Lung Stem Cell Biology and Regenerative Medicine.

Authors:  Michael F Beers; Yuben Moodley
Journal:  Am J Respir Cell Mol Biol       Date:  2017-07       Impact factor: 6.914

Review 2.  New therapeutic targets in idiopathic pulmonary fibrosis. Aiming to rein in runaway wound-healing responses.

Authors:  Neil Ahluwalia; Barry S Shea; Andrew M Tager
Journal:  Am J Respir Crit Care Med       Date:  2014-10-15       Impact factor: 21.405

3.  STAT-3 contributes to pulmonary fibrosis through epithelial injury and fibroblast-myofibroblast differentiation.

Authors:  Mesias Pedroza; Thuy T Le; Katherine Lewis; Harry Karmouty-Quintana; Sarah To; Anuh T George; Michael R Blackburn; David J Tweardy; Sandeep K Agarwal
Journal:  FASEB J       Date:  2015-08-31       Impact factor: 5.191

4.  Grp78 Loss in Epithelial Progenitors Reveals an Age-linked Role for Endoplasmic Reticulum Stress in Pulmonary Fibrosis.

Authors:  Zea Borok; Masafumi Horie; Per Flodby; Hongjun Wang; Yixin Liu; Sivagini Ganesh; Amy L Firth; Parviz Minoo; Changgong Li; Michael F Beers; Amy S Lee; Beiyun Zhou
Journal:  Am J Respir Crit Care Med       Date:  2020-01-15       Impact factor: 21.405

5.  miR-200 family members reduce senescence and restore idiopathic pulmonary fibrosis type II alveolar epithelial cell transdifferentiation.

Authors:  Silvia Moimas; Francesco Salton; Beata Kosmider; Nadja Ring; Maria C Volpe; Karim Bahmed; Luca Braga; Michael Rehman; Simone Vodret; Maria Laura Graziani; Marla R Wolfson; Nathaniel Marchetti; Thomas J Rogers; Mauro Giacca; Gerard J Criner; Serena Zacchigna; Marco Confalonieri
Journal:  ERJ Open Res       Date:  2019-12-16

6.  Pulmonary Alveolar Stem Cell Senescence, Apoptosis, and Differentiation by p53-Dependent and -Independent Mechanisms in Telomerase-Deficient Mice.

Authors:  Kexiong Zhang; Lihui Wang; Xiaojing Hong; Hao Chen; Yao Shi; Yingying Liu; Jun Liu; Jun-Ping Liu
Journal:  Cells       Date:  2021-10-26       Impact factor: 6.600

7.  C/EBP homologous protein promotes Sonic Hedgehog secretion from type II alveolar epithelial cells and activates Hedgehog signaling pathway of fibroblast in pulmonary fibrosis.

Authors:  Xiaoyu Yang; Wei Sun; Xiaoyan Jing; Qian Zhang; Hui Huang; Zuojun Xu
Journal:  Respir Res       Date:  2022-04-08

8.  Towards a global initiative for fibrosis treatment (GIFT).

Authors:  Maria Molina-Molina; Alvar Agusti; Bruno Crestani; David A Schwartz; Melanie Königshoff; Rachel C Chambers; Toby M Maher; Rosa Faner; Ana Lucia Mora; Mauricio Rojas; Katerina M Antoniou; Jacobo Sellares
Journal:  ERJ Open Res       Date:  2017-12-01
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.