OBJECTIVE: To evaluate the efficacy of Banxiaxiexin Tang compared with Western Medicine in the treatment of functional dyspepsia (FD) through Meta-analysis. METHODS: Literature was searched in the following databases: MEDLINE, Excerpta Medica Database, Chinese Medical Current Contents, China Science and Technology Database, Chinese Biomedical Literature Database, and China National Knowledge Infrastructure. Randomized controlled trials evaluating the efficacy of Banxiaxiexin Tang for the treatment of FD were selected according to certain standards including clear general situation of patients, specific diagnostic criteria, definite clinical outcomes, etc. Articles were evaluated with quality assessment standards in the Cochrane Handbook for Systematic Reviews of Interventions. Meta-analysis was conducted with RevMan 5.0.23 software. RESULTS: Ten articles with a total of 972 patients were included. The comparison of efficacy between Banxiaxiexin Tang and Western Medicine showed a combined effect size [OR = 2.75, 95% CI (1.86-4.07)] and combined effect of value of Z = 5.07 (P < 0.000 01), suggesting a significant difference between the groups. CONCLUSION: Banxiaxiexin Tang was more effective than Western Medicine in treating FD.
OBJECTIVE: To evaluate the efficacy of Banxiaxiexin Tang compared with Western Medicine in the treatment of functional dyspepsia (FD) through Meta-analysis. METHODS: Literature was searched in the following databases: MEDLINE, Excerpta Medica Database, Chinese Medical Current Contents, China Science and Technology Database, Chinese Biomedical Literature Database, and China National Knowledge Infrastructure. Randomized controlled trials evaluating the efficacy of Banxiaxiexin Tang for the treatment of FD were selected according to certain standards including clear general situation of patients, specific diagnostic criteria, definite clinical outcomes, etc. Articles were evaluated with quality assessment standards in the Cochrane Handbook for Systematic Reviews of Interventions. Meta-analysis was conducted with RevMan 5.0.23 software. RESULTS: Ten articles with a total of 972 patients were included. The comparison of efficacy between Banxiaxiexin Tang and Western Medicine showed a combined effect size [OR = 2.75, 95% CI (1.86-4.07)] and combined effect of value of Z = 5.07 (P < 0.000 01), suggesting a significant difference between the groups. CONCLUSION: Banxiaxiexin Tang was more effective than Western Medicine in treating FD.
Authors: Michael H K Chu; Irene X Y Wu; Robin S T Ho; Charlene H L Wong; Anthony L Zhang; Yan Zhang; Justin C Y Wu; Vincent C H Chung Journal: Therap Adv Gastroenterol Date: 2018-07-16 Impact factor: 4.409