Literature DB >> 24783115

Cerebral stroke after valvular surgery in young patients: case studies.

Ravi Ghatanatti1, Sundeep Sanjivan Tirkey1, Anita Teli2.   

Abstract

Intracranial haemorrhage (ICH) is a dreaded complication caused by oral anticoagulants (OAC) after valvular heart surgeries. Anticoagulant use in conventional doses increases the risk of ICH 7-10 fold. Intracerebral haematomas constitute 70% of the anticoagulant-related intracranial haemorrhages, with mortalities approaching 60%. Predisposing factors for anticoagulant-related ICH in Indian patients are unique as compared to those seen in their western counterparts. In anticoagulated patients, ICH evolves rapidly within hours; hence, emergency reversal of anticoagulation is crucial. We are reporting four cases of cerebral strokes which followed valvular surgeries in our institution, who were admitted during August 2012 to July 2013. There is an increasing need to educate the patients and update the physicians regarding the various issues which are involved in anticoagulation management.

Entities:  

Keywords:  Cardiac surgery; Intracranial haemorrhage; Oral anticoagulants

Year:  2014        PMID: 24783115      PMCID: PMC4003619          DOI: 10.7860/JCDR/2014/7391.4143

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  6 in total

1.  Major bleeding in outpatients treated with warfarin: incidence and prediction by factors known at the start of outpatient therapy.

Authors:  C S Landefeld; L Goldman
Journal:  Am J Med       Date:  1989-08       Impact factor: 4.965

2.  Is INR between 2.0 and 3.0 the optimal level for Chinese patients on warfarin therapy for moderate-intensity anticoagulation?

Authors:  J H S You; F W H Chan; R S M Wong; G Cheng
Journal:  Br J Clin Pharmacol       Date:  2005-05       Impact factor: 4.335

3.  Outpatient oral anticoagulant management--an audit of 82 patients.

Authors:  N Kakkar; R Kaur; Mary John
Journal:  J Assoc Physicians India       Date:  2005-10

4.  Incidence of major bleeding complication of warfarin therapy in Japanese patients with atrial fibrillation.

Authors:  Shinya Suzuki; Takeshi Yamashita; Takeshi Kato; Tadashi Fujino; Koichi Sagara; Hitoshi Sawada; Tadanori Aizawa; Long-Tai Fu
Journal:  Circ J       Date:  2007-05       Impact factor: 2.993

Review 5.  When should you restart anticoagulation in patients who suffer an intracranial bleed who also have a prosthetic valve?

Authors:  Dinesh Chandra; Anubhav Gupta; Vijay Grover; Vijay Kumar Gupta
Journal:  Interact Cardiovasc Thorac Surg       Date:  2013-01-03

6.  Venous thromboembolism, thrombophilia, antithrombotic therapy, and pregnancy: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition).

Authors:  Shannon M Bates; Ian A Greer; Ingrid Pabinger; Shoshanna Sofaer; Jack Hirsh
Journal:  Chest       Date:  2008-06       Impact factor: 9.410

  6 in total

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