Literature DB >> 24783104

Sertoli-leydig cell tumor of ovary- a diagnostic dilemma.

Rohini Dhanya C S1, Somanath Padhi2, Renu G'boy Varghese3.   

Abstract

Sertoli Leydig Cell Tumours (SLCTs) are rare, unilateral, sex cord stromal tumours of ovary, which constitute less than 1% of all the ovarian neoplasms. These tumours can be functionally diverse and they may have heterologous elements. We aim to report a case of a 25-year- old woman who presented with suprapubic pain of 5 days duration, a unilateral adnexal mass, hypertestosteronism without virilization. Intraoperative frozen section of the unilateral salpingo-oophorectomy specimen was suggestive of granulosa cell tumour. Histopathological examination, supplemented with alpha-inhibin immunohistochemistry, was diagnostic of Meyer's type II SLCT. Clinical presentation, pathology and the diagnostic pitfalls in the present case have been presented with a brief review of literature.

Entities:  

Keywords:  Alfa-Inhibin; Frozen section; Ovary; Sertoli-Leydig cell tumour

Year:  2014        PMID: 24783104      PMCID: PMC4003607          DOI: 10.7860/JCDR/2014/7000.4099

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  5 in total

1.  Bilateral Sertoli-Leydig cell tumor of the ovary: a rare case report.

Authors:  Kiran Alam; Veena Maheshwari; Seema Rashid; Shruti Bhargava
Journal:  Indian J Pathol Microbiol       Date:  2009 Jan-Mar       Impact factor: 0.740

2.  Frozen section and the surgical pathologist: a point of view.

Authors:  Jerome B Taxy
Journal:  Arch Pathol Lab Med       Date:  2009-07       Impact factor: 5.534

3.  Adolescent ovarian tumors: a clinicopathlogical review of 15 cases.

Authors:  Abeera Choudry; Naila Bangash; Ayesha Malik; Humaira Choudry
Journal:  J Ayub Med Coll Abbottabad       Date:  2008 Oct-Dec

4.  Sertoli cell tumors of the ovary: a clinicopathologic and immunohistochemical study of 54 cases.

Authors:  Esther Oliva; Teresa Alvarez; Robert H Young
Journal:  Am J Surg Pathol       Date:  2005-02       Impact factor: 6.394

5.  Granulosa cell, Sertoli-Leydig cell, and unclassified sex cord-stromal tumors associated with pregnancy: a clinicopathological analysis of thirty-six cases.

Authors:  R H Young; A G Dudley; R E Scully
Journal:  Gynecol Oncol       Date:  1984-06       Impact factor: 5.482

  5 in total
  2 in total

1.  Ovarian Sertoli-Leydig Cell Tumour with Heterologus Elements Masquerading as Mucinous Tumour on Frozen Section: A Case Report.

Authors:  Swati Sharma; Manna Valiathan; Sandeep Kumar; Sukriti Kapoor
Journal:  J Clin Diagn Res       Date:  2015-07-01

2.  Frozen Section Diagnostic Pitfalls of Sertoli-Leydig Cell Tumor with Heterologous Elements.

Authors:  Ashley Burris; Caleb Hixson; Nathaniel Smith
Journal:  Case Rep Pathol       Date:  2018-07-25
  2 in total

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