Literature DB >> 24783100

Benign Hepatic Mesenchymal Hamartoma (HMH) - A Case Report.

Shaileshkumar Radheshyam Patel1, Vatsala Misra2, Kachnar Verma3, Pooja Gupta1, Vishal Dhingra4.   

Abstract

A one-year-old male child presented with progressive enlargement of abdomen and loss of appetite which he had suffered from, since 4 months. Physical examination showed a palpable mass in right hypochondrium. Ultrasonography and MRI showed a solid mass arising from right lobe of liver. The resected mass was well encapsulated, yellowish white in colour and it measured 20 x 18 x 17cm. Cut surface showed a Nutmeg like appearance. Histology showed a well-defined, fibrous capsule with numerous ducts which were lined by flat to low cuboidal epithelium and which were surrounded by concentric layers of fibrous tissue which showed myxoid changes at places. Intervening area showed normal appearing hepatocytes with clear cell changes, dilated congested sinusoids, along with extramedullary haematopoiesis. Based on distinctive morphological features, a histological diagnosis of Benign Hepatic Mesenchymal Hamartoma of liver was made. IHC was not done, as no specific marker has been described for making a differential diagnosis. Benign Hepatic Mesenchymal Hamrtoma (HMH) of liver is an extremely rare tumour of childhood and therefore, the case was considered worth documentation.

Entities:  

Keywords:  Bile duct; Extramedullary hematopoiesis; Liver; Mesenchymal hamartoma; Paediatric tumour

Year:  2014        PMID: 24783100      PMCID: PMC4003603          DOI: 10.7860/JCDR/2014/6522.4129

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  4 in total

1.  Hepatic undifferentiated embryonal sarcoma: malignant evolution of mesenchymal hamartoma? Study of one case with immunohistochemical and flow cytometric emphasis.

Authors:  H Begueret; H Trouette; P Vielh; C Laurent; G MacGrogan; M Delsol; G Belleannee; B Masson; A De Mascarel
Journal:  J Hepatol       Date:  2001-01       Impact factor: 25.083

Review 2.  Hepatic mesenchymal hamartoma: a short review.

Authors:  Masood A Siddiqui; Barbara J McKenna
Journal:  Arch Pathol Lab Med       Date:  2006-10       Impact factor: 5.534

Review 3.  Hepatic mesenchymal hamartoma.

Authors:  J-B Yen; M-S Kong; J-N Lin
Journal:  J Paediatr Child Health       Date:  2003-11       Impact factor: 1.954

4.  Long-term follow up of mesenchymal hamartoma of liver--single center study.

Authors:  Anand Pandey; Ajay N Gangopadhyay; Shiv P Sharma; Vijayendra Kumar; Dinesh K Gupta; Saroj C Gopal; Shashikant C Patne
Journal:  Saudi J Gastroenterol       Date:  2011 Jan-Feb       Impact factor: 2.485

  4 in total
  2 in total

1.  Surgery is the preferred treatment for bile duct hamartomas.

Authors:  Xiao-Yu Yang; Hai-Bo Zhang; Bin Wu; Ai-Jun Li; Xiao-Hui Fu
Journal:  Mol Clin Oncol       Date:  2017-07-31

Review 2.  A 4 and a half years old boy with mesenchymal hamartomas in the left lateral lobe of the liver: A case report and literature review.

Authors:  Wei Liao; Binhao Zhang; Wei Zhang; Lin Chen; Wanguang Zhang; Bixiang Zhang; Xiaoping Chen
Journal:  Medicine (Baltimore)       Date:  2017-08       Impact factor: 1.889

  2 in total

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