| Literature DB >> 24782343 |
Yuki Matsumura1, Takahiro Suzuki, Akira Sakakura, Kazuaki Ishihara.
Abstract
The first diastereo- and enantioselective inverse electron demand hetero-Diels-Alder reaction of β,γ-unsaturated α-ketoesters with allylsilanes is described. Chiral copper(II) catalysts successfully activate the β,γ-unsaturated α-ketoesters and promote the reaction with allylsilanes with excellent enantioselectivities. This process represents a new entry to chiral oxanes.Entities:
Keywords: Lewis acid; asymmetric catalysis; copper; cycloaddition; heterocycles
Year: 2014 PMID： 24782343 DOI： 10.1002/anie.201402934
Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN： 1433-7851 Impact factor: 15.336