Literature DB >> 24780475

Nonextracorporeal methods for decreasing uremic solute concentration: a future way to go?

Björn Meijers1, Griet Glorieux2, Ruben Poesen3, Stephan J L Bakker4.   

Abstract

The uremic milieu is consequential to a disrupted balance between availability of retention solutes and the excretory capacity of the kidneys. Although metabolism is the prime contributor to the internal milieu, a significant fraction of uremic retention solutes originates from other sources. The main route of entrance is via the intestinal tract, directly from the diet and indirectly from commensal microbial metabolism. This latter dynamic interplay between the intestines and kidney has been coined the gut-kidney axis. This review summarizes current understanding of the gut-kidney axis and explores the impact of dietary and other nonextracorporeal therapeutic interventions in patients with chronic kidney disease.
Copyright © 2014 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Uremic retention solutes; diet; intestine; metabolism; microbiome

Mesh：

Year:  2014        PMID： 24780475     DOI： 10.1016/j.semnephrol.2014.02.012

Source DB:  PubMed          Journal:  Semin Nephrol        ISSN： 0270-9295            Impact factor:   5.299


  12 in total

Review 1.  The role of the intestinal microbiota in uremic solute accumulation: a focus on sulfur compounds.

Authors:  Alessandra F Perna; Griet Glorieux; Miriam Zacchia; Francesco Trepiccione; Giovanna Capolongo; Carmela Vigorito; Evgeniya Anishchenko; Diego Ingrosso
Journal:  J Nephrol       Date:  2019-01-23       Impact factor: 3.902

2.  HEMO Revisited: Why Kt/Vurea Only Tells Part of the Story.

Authors:  Björn Meijers; Raymond Vanholder
Journal:  J Am Soc Nephrol       Date:  2016-06-07       Impact factor: 10.121

3.  The Influence of Prebiotic Arabinoxylan Oligosaccharides on Microbiota Derived Uremic Retention Solutes in Patients with Chronic Kidney Disease: A Randomized Controlled Trial.

Authors:  Ruben Poesen; Pieter Evenepoel; Henriette de Loor; Jan A Delcour; Christophe M Courtin; Dirk Kuypers; Patrick Augustijns; Kristin Verbeke; Björn Meijers
Journal:  PLoS One       Date:  2016-04-21       Impact factor: 3.240

Review 4.  Proteomic Investigations into Hemodialysis Therapy.

Authors:  Mario Bonomini; Vittorio Sirolli; Luisa Pieroni; Paolo Felaco; Luigi Amoroso; Andrea Urbani
Journal:  Int J Mol Sci       Date:  2015-12-10       Impact factor: 5.923

Review 5.  Biochemical and Clinical Impact of Organic Uremic Retention Solutes: A Comprehensive Update.

Authors:  Raymond Vanholder; Anneleen Pletinck; Eva Schepers; Griet Glorieux
Journal:  Toxins (Basel)       Date:  2018-01-08       Impact factor: 4.546

Review 6.  Immune Dysfunction in Uremia 2020.

Authors:  Gerald Cohen
Journal:  Toxins (Basel)       Date:  2020-07-05       Impact factor: 4.546

7.  Gut Microbiota as a Source of Uremic Toxins.

Authors:  Vasily A Popkov; Anastasia A Zharikova; Evgenia A Demchenko; Nadezda V Andrianova; Dmitry B Zorov; Egor Y Plotnikov
Journal:  Int J Mol Sci       Date:  2022-01-01       Impact factor: 5.923

8.  Uraemic toxins and new methods to control their accumulation: game changers for the concept of dialysis adequacy.

Authors:  Griet Glorieux; James Tattersall
Journal:  Clin Kidney J       Date:  2015-06-01

9.  The effect of isohydric hemodialysis on the binding and removal of uremic retention solutes.

Authors:  Aleksey Etinger; Sumit R Kumar; William Ackley; Leland Soiefer; Jonathan Chun; Prabjhot Singh; Eric Grossman; Albert Matalon; Robert S Holzman; Bjorn Meijers; Jerome Lowenstein
Journal:  PLoS One       Date:  2018-02-22       Impact factor: 3.240

10.  Zebrafish, a Novel Model System to Study Uremic Toxins: The Case for the Sulfur Amino Acid Lanthionine.

Authors:  Alessandra F Perna; Evgeniya Anishchenko; Carmela Vigorito; Miriam Zacchia; Francesco Trepiccione; Salvatore D'Aniello; Diego Ingrosso
Journal:  Int J Mol Sci       Date:  2018-04-29       Impact factor: 5.923
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