Literature DB >> 24778929

GM-CSF facilitates the development of inflammation-associated colorectal carcinoma.

Guojiang Chen1, Gencheng Han1, Beifen Shen1, Yan Li1.   

Abstract

The granulocyte macrophage colony-stimulating factor (GM-CSF) is known to play a protective role in intestinal inflammation. However, the effects of GM-CSF on the progression of colitis to colorectal carcinoma have long remained unclear. We have recently demonstrated that GM-CSF produced by colonic epithelial cells promotes colorectal tumorigenesis by stimulating the secretion of vascular endothelial growth factor.

Entities:  

Keywords:  GM-CSF; VEGF; colitis; colonic epithelial cell; colorectal carcinoma

Year:  2014        PMID： 24778929      PMCID： PMC4000268          DOI： 10.4161/onci.28186

Source DB:  PubMed          Journal:  Oncoimmunology        ISSN： 2162-4011            Impact factor:   8.110


  10 in total

Review 1.  Cytokines: from gut inflammation to colorectal cancer.

Authors:  Massimo C Fantini; Francesco Pallone
Journal:  Curr Drug Targets       Date:  2008-05       Impact factor: 3.465

Review 2.  Inflammation and cancer: back to Virchow?

Authors:  F Balkwill; A Mantovani
Journal:  Lancet       Date:  2001-02-17       Impact factor: 79.321

3.  NF-kappaB in breast cancer cells promotes osteolytic bone metastasis by inducing osteoclastogenesis via GM-CSF.

Authors:  Bae Keun Park; Honglai Zhang; Qinghua Zeng; Jinlu Dai; Evan T Keller; Thomas Giordano; Keni Gu; Veena Shah; Lei Pei; Richard J Zarbo; Laurie McCauley; Songtao Shi; Shaoqiong Chen; Cun-Yu Wang
Journal:  Nat Med       Date:  2006-12-10       Impact factor: 53.440

4.  Increased secretion of granulocyte-macrophage colony-stimulating factor in mucosal lesions of inflammatory bowel disease.

Authors:  M Noguchi; N Hiwatashi; Z X Liu; T Toyota
Journal:  Digestion       Date:  2001       Impact factor: 3.216

5.  Tumor-derived granulocyte-macrophage colony-stimulating factor regulates myeloid inflammation and T cell immunity in pancreatic cancer.

Authors:  Lauren J Bayne; Gregory L Beatty; Nirag Jhala; Carolyn E Clark; Andrew D Rhim; Ben Z Stanger; Robert H Vonderheide
Journal:  Cancer Cell       Date:  2012-06-12       Impact factor: 31.743

6.  GM-CSF produced by nonhematopoietic cells is required for early epithelial cell proliferation and repair of injured colonic mucosa.

Authors:  Laia Egea; Christopher S McAllister; Omar Lakhdari; Ivelina Minev; Steve Shenouda; Martin F Kagnoff
Journal:  J Immunol       Date:  2013-01-16       Impact factor: 5.422

7.  Tumor-derived GM-CSF promotes inflammatory colon carcinogenesis via stimulating epithelial release of VEGF.

Authors:  Yi Wang; Gencheng Han; Ke Wang; Guijun Liu; Renxi Wang; He Xiao; Xinying Li; Chunmei Hou; Beifen Shen; Renfeng Guo; Yan Li; Guojiang Chen
Journal:  Cancer Res       Date:  2013-12-23       Impact factor: 12.701

8.  Granulocyte-macrophage colony-stimulating factor elicits bone marrow-derived cells that promote efficient colonic mucosal healing.

Authors:  Eric Bernasconi; Laurent Favre; Michel H Maillard; Daniel Bachmann; Catherine Pythoud; Hanifa Bouzourene; Ed Croze; Sharlene Velichko; John Parkinson; Pierre Michetti; Dominique Velin
Journal:  Inflamm Bowel Dis       Date:  2010-03       Impact factor: 5.325

9.  The role of granulocyte macrophage-colony-stimulating factor in acute intestinal inflammation.

Authors:  Yinghua Xu; Nicholas H Hunt; Shisan Bao
Journal:  Cell Res       Date:  2008-12       Impact factor: 25.617

10.  VEGF receptor signaling links inflammation and tumorigenesis in colitis-associated cancer.

Authors:  Maximilian J Waldner; Stefan Wirtz; André Jefremow; Moritz Warntjen; Clemens Neufert; Raja Atreya; Christoph Becker; Benno Weigmann; Michael Vieth; Stefan Rose-John; Markus F Neurath
Journal:  J Exp Med       Date:  2010-11-22       Impact factor: 14.307
  10 in total
  7 in total

Review 1.  Trial watch: Dendritic cell-based anticancer therapy.

Authors:  Norma Bloy; Jonathan Pol; Fernando Aranda; Alexander Eggermont; Isabelle Cremer; Wolf Hervé Fridman; Jitka Fučíková; Jérôme Galon; Eric Tartour; Radek Spisek; Madhav V Dhodapkar; Laurence Zitvogel; Guido Kroemer; Lorenzo Galluzzi
Journal:  Oncoimmunology       Date:  2014-12-21       Impact factor: 8.110

2.  Colorectal cancer extracellular acidosis decreases immune cell killing and is partially ameliorated by pH-modulating agents that modify tumor cell cytokine profiles.

Authors:  Kelsey E Huntington; Anna Louie; Lanlan Zhou; Attila A Seyhan; Aaron Wp Maxwell; Wafik S El-Deiry
Journal:  Am J Cancer Res       Date:  2022-01-15       Impact factor: 6.166

3.  A high-throughput customized cytokinome screen of colon cancer cell responses to small-molecule oncology drugs.

Authors:  Kelsey E Huntington; Anna Louie; Lanlan Zhou; Wafik S El-Deiry
Journal:  Oncotarget       Date:  2021-09-28

4.  GM-CSF Nitration Is a New Driver of Myeloid Suppressor Cell Activity in Tumors.

Authors:  Bianca Calì; Andrielly H R Agnellini; Chiara Cioccarelli; Ricardo Sanchez-Rodriguez; Andrea Predonzani; Giulia Ilaria Toffolo; Antonella Viola; Vincenzo Bronte; Giorgio Arrigoni; Francesco Zonta; Laura Albertoni; Claudia Mescoli; Ilaria Marigo; Barbara Molon
Journal:  Front Immunol       Date:  2021-10-05       Impact factor: 7.561

Review 5.  Molecular Mechanisms of Tumor Immunomodulation in the Microenvironment of Colorectal Cancer.

Authors:  Dorothea Plundrich; Sophia Chikhladze; Stefan Fichtner-Feigl; Reinhild Feuerstein; Priscilla S Briquez
Journal:  Int J Mol Sci       Date:  2022-03-03       Impact factor: 5.923

Review 6.  The Role of Inflammatory Cytokines in the Pathogenesis of Colorectal Carcinoma-Recent Findings and Review.

Authors:  Jędrzej Borowczak; Krzysztof Szczerbowski; Mateusz Maniewski; Adam Kowalewski; Marlena Janiczek-Polewska; Anna Szylberg; Andrzej Marszałek; Łukasz Szylberg
Journal:  Biomedicines       Date:  2022-07-11

7.  Pregnancy-specific glycoprotein 9 (PSG9), a driver for colorectal cancer, enhances angiogenesis via activation of SMAD4.

Authors:  Lei Yang; Shusheng Hu; Jinjing Tan; Xiaojing Zhang; Wen Yuan; Qian Wang; Lingling Xu; Jian Liu; Zheng Liu; Yanjun Jia; Xiaoxi Huang
Journal:  Oncotarget       Date:  2016-09-20
  7 in total

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