Literature DB >> 2477278

RNA degrading activity is tightly associated with the multicatalytic proteinase, ingensin.

T Tsukahara1, K Tanaka, T Ogawa, S Ishiura, R Funabiki, H Sugita.   

Abstract

The multicatalytic proteinase, ingensin, was purified to homogeneity from chicken liver. rRNA-degrading activity was co-eluted with the purified multicatalytic proteinase from a TSK-3000SW column. This RNA-degrading activity was inactivated by heat treatment and the addition of a low concentration of SDS. Therefore, the RNA-degrading activity co-eluted with the multicatalytic proteinase was not due to contamination by low-molecular-mass RNases. These results strongly suggest that this RNA-degrading activity was tightly associated with the multicatalytic proteinase, ingensin.

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Year:  1989        PMID： 2477278     DOI： 10.1016/0014-5793(89)81086-5

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  10 in total

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Authors:  H P Schmid; M N Pouch; F Petit; M H Dadet; S Badaoui; G Boissonnet; J Buri; V Norris; Y Briand
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Authors:  J M Peters; M J Walsh; W W Franke
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  10 in total

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