Literature DB >> 24771967

Efficacy and safety of a topical carbon suspension photoenhancer adjunctive to intense pulsed light treatment for pigmented lesions in Japanese patients: A pilot study.

Yushi Kawasaki1, Seiji Kawana2.   

Abstract

BACKGROUND AND AIMS: Pigmented lesions, e.g., senile lentigo and seborrheic keratosis are commonly seen in photodamaged skin in the Japanese general population. The use of the laser to treat such lesions is often painful, and intense pulsed light (IPL) systems have become widely used. Clearly demarcated pigmented lesions may be identified easily and treated with IPL. Less well demarcated lesions, however, which are very difficult to identify or thick melanogesic lesions like seborrheic keratosis represent one of the most challenging conditions to be treated using IPL. This pilot study evaluated carbon suspension-assisted IPL treatment of such lesions. SUBJECTS AND METHODS: Three female Japanese patients, Fitzpatrick skin type III-IV, comprised the subjects, aged 58, 78 and 85, with indistinct senile lentigines or thick seborrheic keratoses. The lesions were painted or demarcated with a carbon-based ink from a commercially-available Japanese writing instrument (Fude-pen™, Pentel, Japan) consisting of a brush-like pen nib with a refillable or replaceable ink reservoir, and then treated with a broadband (560 - 1200 nm) IPL system.
RESULTS: The poorly-demarcated lesions were quickly and easily marked with the pen, and the IPL treatments were well-tolerated. All patients had good improvement in their painted pigmented lesions based on the overall evaluation, compared with unpainted ones. Side effects after treatment, such as hyperpigmentation, persistent erythema, and scarring, were minimal.
CONCLUSIONS: Topical carbon suspension-assisted IPL treatment could be a good option for patients with indistinct pigmented or thick melanogenesic lesions. Adverse reactions to this treatment were minimal and the results acceptable, though appropriate lesions need to be chosen carefully.

Entities:  

Year:  2014        PMID: 24771967      PMCID: PMC3999427          DOI: 10.5978/islsm.14-OR-01

Source DB:  PubMed          Journal:  Laser Ther        ISSN: 0898-5901


  13 in total

1.  A comparison of Q-switched alexandrite laser and intense pulsed light for the treatment of freckles and lentigines in Asian persons: a randomized, physician-blinded, split-face comparative trial.

Authors:  Chia-Chen Wang; Yuh-Mou Sue; Chih-Hsiung Yang; Chih-Kang Chen
Journal:  J Am Acad Dermatol       Date:  2006-05       Impact factor: 11.527

2.  The combination of glycolic acid peels with a topical regimen in the treatment of melasma in dark-skinned patients: a comparative study.

Authors:  Rashmi Sarkar; Charandeep Kaur; Mala Bhalla; Amrinder J Kanwar
Journal:  Dermatol Surg       Date:  2002-09       Impact factor: 3.398

Review 3.  Intense pulsed light (IPL): a review.

Authors:  Philipp Babilas; Stephan Schreml; Rolf-Markus Szeimies; Michael Landthaler
Journal:  Lasers Surg Med       Date:  2010-02       Impact factor: 4.025

4.  Comparison study of intense pulsed light versus a long-pulse pulsed dye laser in the treatment of facial skin rejuvenation.

Authors:  Taro Kono; William Frederick Groff; Hiroyuki Sakurai; Masaki Takeuchi; Takashi Yamaki; Kazutaka Soejima; Motohiro Nozaki
Journal:  Ann Plast Surg       Date:  2007-11       Impact factor: 1.539

5.  Benefits of using a hydroquinone/tretinoin skin care system in patients undergoing intense pulsed light therapy for photorejuvenation: a placebo-controlled study.

Authors:  Katrina E Woodhall; Mitchel P Goldman; Michael H Gold; Julie Biron
Journal:  J Drugs Dermatol       Date:  2009-09       Impact factor: 2.114

6.  Safety and efficacy of glycolic acid facial peel in Indian women with melasma.

Authors:  S M Javaheri; S Handa; I Kaur; B Kumar
Journal:  Int J Dermatol       Date:  2001-05       Impact factor: 2.736

7.  Prospective study of topical 5-aminolevulinic acid photodynamic therapy for the treatment of moderate to severe acne vulgaris in Chinese patients.

Authors:  Hong-Wei Wang; Ting Lv; Ling-Lin Zhang; Ming-Xia Guo; Herbert Stepp; Kui Yang; Zheng Huang; Xiu-Li Wang
Journal:  J Cutan Med Surg       Date:  2012 Sep-Oct       Impact factor: 2.092

8.  Intense pulsed light for the treatment of rosacea and telangiectasias.

Authors:  Ramtin Kassir; Aparanjita Kolluru; Martin Kassir
Journal:  J Cosmet Laser Ther       Date:  2011-10       Impact factor: 2.247

9.  Usefulness of retinoic acid in the treatment of melasma.

Authors:  M A Pathak; T B Fitzpatrick; E W Kraus
Journal:  J Am Acad Dermatol       Date:  1986-10       Impact factor: 11.527

Review 10.  European guidelines for topical photodynamic therapy part 2: emerging indications--field cancerization, photorejuvenation and inflammatory/infective dermatoses.

Authors:  C A Morton; R-M Szeimies; A Sidoroff; L R Braathen
Journal:  J Eur Acad Dermatol Venereol       Date:  2012-11-26       Impact factor: 6.166

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