Literature DB >> 24769292

The ontogenesis of language lateralization and its relation to handedness.

Sebastian Ocklenburg1, Christian Beste2, Larissa Arning3, Jutta Peterburs4, Onur Güntürkün5.   

Abstract

Dominance of the left hemisphere for many aspects of speech production and perception is one of the best known examples of functional hemispheric asymmetries in the human brain. Classic theories about its ontogenesis assume that it is determined by the same ontogenetic factors as handedness because the two traits are correlated to some extent. However, the strength of this correlation depends on the measures used to assess the two traits, and the neurophysiological basis of language lateralization is different from that of handedness. Therefore, we argue that although the two traits show partial pleiotropy, there is also a substantial amount of independent ontogenetic influences for each of them. This view is supported by several recent genetic and neuroscientific studies that are reviewed in the present article.
Copyright © 2014 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Functional Hemispheric asymmetries; Laterality; Lateralization; Ontogenesis; Speech

Mesh:

Year:  2014        PMID: 24769292     DOI: 10.1016/j.neubiorev.2014.04.008

Source DB:  PubMed          Journal:  Neurosci Biobehav Rev        ISSN: 0149-7634            Impact factor:   8.989


  29 in total

1.  Left-Right Axis Differentiation and Functional Lateralization: a Haplotype in the Methyltransferase Encoding Gene SETDB2 Might Mediate Handedness in Healthy Adults.

Authors:  Sebastian Ocklenburg; Larissa Arning; Wanda M Gerding; Jan G Hengstler; Jörg T Epplen; Onur Güntürkün; Christian Beste; Denis A Akkad
Journal:  Mol Neurobiol       Date:  2015-11-16       Impact factor: 5.590

2.  Ultrasonic vocalization changes and FOXP2 expression after experimental stroke.

Authors:  Sarah J Doran; Cassandra Trammel; Sharon E Benashaski; Venugopal Reddy Venna; Louise D McCullough
Journal:  Behav Brain Res       Date:  2015-01-31       Impact factor: 3.332

3.  Linkage analysis in a Dutch population isolate shows no major gene for left-handedness or atypical language lateralization.

Authors:  Metten Somers; Roel A Ophoff; Maartje F Aukes; Rita M Cantor; Marco P Boks; Meenakshi Dauwan; Kees L de Visser; René S Kahn; Iris E Sommer
Journal:  J Neurosci       Date:  2015-06-10       Impact factor: 6.167

4.  Structural Asymmetry in the Frontal and Temporal Lobes Is Associated with PCSK6 VNTR Polymorphism.

Authors:  Gesa Berretz; Larissa Arning; Wanda M Gerding; Patrick Friedrich; Christoph Fraenz; Caroline Schlüter; Jörg T Epplen; Onur Güntürkün; Christian Beste; Erhan Genç; Sebastian Ocklenburg
Journal:  Mol Neurobiol       Date:  2019-05-21       Impact factor: 5.590

5.  PLP1 Gene Variation Modulates Leftward and Rightward Functional Hemispheric Asymmetries.

Authors:  Sebastian Ocklenburg; Wanda M Gerding; Maximilian Raane; Larissa Arning; Erhan Genç; Jörg T Epplen; Onur Güntürkün; Christian Beste
Journal:  Mol Neurobiol       Date:  2018-02-13       Impact factor: 5.590

6.  Lateral preference in Williams-Beuren syndrome is associated with cognition and language.

Authors:  D Pérez-García; R Flores; C Brun-Gasca; L A Pérez-Jurado
Journal:  Eur Child Adolesc Psychiatry       Date:  2014-11-28       Impact factor: 4.785

7.  Cognitive Control Processes and Functional Cerebral Asymmetries: Association with Variation in the Handedness-Associated Gene LRRTM1.

Authors:  Christian Beste; Larissa Arning; Wanda M Gerding; Jörg T Epplen; Alexandra Mertins; Melanie C Röder; Josef J Bless; Kenneth Hugdahl; René Westerhausen; Onur Güntürkün; Sebastian Ocklenburg
Journal:  Mol Neurobiol       Date:  2017-03-21       Impact factor: 5.590

8.  Myelin Genes and the Corpus Callosum: Proteolipid Protein 1 (PLP1) and Contactin 1 (CNTN1) Gene Variation Modulates Interhemispheric Integration.

Authors:  Sebastian Ocklenburg; Wanda M Gerding; Larissa Arning; Erhan Genç; Jörg T Epplen; Onur Güntürkün; Christian Beste
Journal:  Mol Neurobiol       Date:  2016-11-18       Impact factor: 5.590

9.  Differential expression of microRNAs in the human fetal left and right cerebral cortex.

Authors:  Nan Miao; Xiaodong Lai; Zhiwei Zeng; Wenjie Cai; Wanhua Chen; Tao Sun
Journal:  Mol Biol Rep       Date:  2020-08-18       Impact factor: 2.316

10.  Unexpected absence of aphasia following left temporal hemorrhage: a case study with functional neuroimaging to characterize the nature of atypical language localization.

Authors:  Sarah M Schneck; Jillian L Entrup; Melissa C Duff; Stephen M Wilson
Journal:  Neurocase       Date:  2021-03-05       Impact factor: 0.881

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