Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Biological activities of new monohydroxylated brassinosteroid analogues with a carboxylic group in the side chain.

Literature DB >> 24769247

Biological activities of new monohydroxylated brassinosteroid analogues with a carboxylic group in the side chain.

Miroslav Kvasnica¹, Jana Oklestkova², Vaclav Bazgier³, Lucie Rarova¹, Karel Berka⁴, Miroslav Strnad¹.

Abstract

Thirteen monohydroxylated brassinosteroids analogues were synthesized and tested for their biological activity in plant and animal systems. The cytotoxic activity of the products was studied using human normal and cancer cell lines with 28-homocastasterone as positive control, their brassinolide type activity was established using the bean second-internode test with 24-epibrassinolide as standard.

Entities: Chemical Disease Species

Keywords: Anticancer activity; Brassinosteroids; Molecular docking; Organic synthesis; Plant bioassays; Receptor kinase BRI1

Mesh：

Substances：

Year: 2014 PMID： 24769247 DOI： 10.1016/j.steroids.2014.04.007

Source DB: PubMed Journal: Steroids ISSN： 0039-128X Impact factor: 2.668

Keyword Cloud
Cited

6 in total

1. Insights into the Structural Requirements of Potent Brassinosteroids as Vegetable Growth Promoters Using Second-Internode Elongation as Biological Activity: CoMFA and CoMSIA Studies.

Authors: Karoll Ferrer-Pertuz; Luis Espinoza; Jaime Mella
Journal: Int J Mol Sci Date: 2017-12-17 Impact factor: 5.923

6. PcDWF1, a pear brassinosteroid biosynthetic gene homologous to AtDWARF1, affected the vegetative and reproductive growth of plants.

Authors: Xiaodong Zheng; Yuxiong Xiao; Yike Tian; Shaolan Yang; Caihong Wang
Journal: BMC Plant Biol Date: 2020-03-06 Impact factor: 4.215

6 in total

Biological activities of new monohydroxylated brassinosteroid analogues with a carboxylic group in the side chain.

1. Insights into the Structural Requirements of Potent Brassinosteroids as Vegetable Growth Promoters Using Second-Internode Elongation as Biological Activity: CoMFA and CoMSIA Studies.

2. Synthesis of New Brassinosteroid 24-Norcholane Type Analogs Conjugated in C-3 with Benzoate Groups.

3. Synthesis and Biological Activity of Brassinosteroid Analogues with a Nitrogen-Containing Side Chain.

4. Biological Activities and Molecular Docking of Brassinosteroids 24-Norcholane Type Analogs.

5. Synthesis and Structural Determination of New Brassinosteroid 24-Nor-5α-Cholane Type Analogs.

6. PcDWF1, a pear brassinosteroid biosynthetic gene homologous to AtDWARF1, affected the vegetative and reproductive growth of plants.