Literature DB >> 24767830

Successful treatment of juvenile xanthogranuloma using bevacizumab.

Noy Ashkenazy1, Christopher R Henry2, Ashkan M Abbey3, Craig A McKeown1, Audina M Berrocal1, Timothy G Murray4.   

Abstract

Juvenile xanthogranuloma (JXG) is an uncommon non-Langerhans cell histiocytic disorder that occurs predominantly in infants. Traditional treatment of ocular JXG involves the administration of topical or local corticosteroids. We treated 2 children with JXG refractory to local corticosteroid therapy with off-label intraocular bevacizumab. To our knowledge, this is the first report of successful use of bevacizumab for ocular JXG.
Copyright © 2014 American Association for Pediatric Ophthalmology and Strabismus. Published by Mosby, Inc. All rights reserved.

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Year:  2014        PMID: 24767830     DOI: 10.1016/j.jaapos.2014.01.007

Source DB:  PubMed          Journal:  J AAPOS        ISSN: 1091-8531            Impact factor:   1.220


  4 in total

1.  [Yellowish, prominent tumor of the corneal periphery].

Authors:  M Zimmermann; J Wasielica-Poslednik; W Lisch; N Pfeiffer; A Gericke
Journal:  Ophthalmologe       Date:  2018-06       Impact factor: 1.059

2.  Intraocular juvenile xanthogranuloma of the iris in an adult patient.

Authors:  Elias Flockerzi; Tobias Hager; Berthold Seitz
Journal:  Am J Ophthalmol Case Rep       Date:  2016-12-06

3.  Juvenile xanthogranuloma involving concurrent iris and skin: Clinical, pathological and molecular pathological evaluations.

Authors:  Peter Meyer; Elisabeth Graeff; Corina Kohler; Francis Munier; Elisabeth Bruder
Journal:  Am J Ophthalmol Case Rep       Date:  2017-09-23

4.  Brolucizumab: Evaluation of Compassionate Use of a Complex Anti-VEGF Therapy.

Authors:  Julianna E Murray; Aaron S Gold; Azeema Latiff; Timothy G Murray
Journal:  Clin Ophthalmol       Date:  2021-12-18
  4 in total

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