Literature DB >> 24766883

Promiscuity is not always bad.

Heng Ru1, Pengfei Zhang1, Hao Wu2.   

Abstract

In the recent issue of Cell, Bonham et al. (2014) reveal that the sorting adaptor TIRAP regulates the assembly of the Myddosome upon Toll-like receptor activation from both the cell surface and endosomes through its promiscuous binding to lipids.
Copyright © 2014 Elsevier Inc. All rights reserved.

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Year:  2014        PMID: 24766883      PMCID: PMC4053647          DOI: 10.1016/j.molcel.2014.04.009

Source DB:  PubMed          Journal:  Mol Cell        ISSN: 1097-2765            Impact factor:   17.970


  10 in total

1.  Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4.

Authors:  Masahiro Yamamoto; Shintaro Sato; Hiroaki Hemmi; Hideki Sanjo; Satoshi Uematsu; Tsuneyasu Kaisho; Katsuaki Hoshino; Osamu Takeuchi; Masaya Kobayashi; Takashi Fujita; Kiyoshi Takeda; Shizuo Akira
Journal:  Nature       Date:  2002-11-21       Impact factor: 49.962

Review 2.  Structural insights into the assembly of large oligomeric signalosomes in the Toll-like receptor-interleukin-1 receptor superfamily.

Authors:  Ryan Ferrao; Jixi Li; Elisa Bergamin; Hao Wu
Journal:  Sci Signal       Date:  2012-05-29       Impact factor: 8.192

3.  Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling.

Authors:  Jonathan C Kagan; Ruslan Medzhitov
Journal:  Cell       Date:  2006-06-02       Impact factor: 41.582

4.  MAPPIT analysis of TLR adaptor complexes.

Authors:  Peter Ulrichts; Frank Peelman; Rudi Beyaert; Jan Tavernier
Journal:  FEBS Lett       Date:  2007-01-18       Impact factor: 4.124

5.  Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction.

Authors:  K A Fitzgerald; E M Palsson-McDermott; A G Bowie; C A Jefferies; A S Mansell; G Brady; E Brint; A Dunne; P Gray; M T Harte; D McMurray; D E Smith; J E Sims; T A Bird; L A O'Neill
Journal:  Nature       Date:  2001-09-06       Impact factor: 49.962

6.  A promiscuous lipid-binding protein diversifies the subcellular sites of toll-like receptor signal transduction.

Authors:  Kevin S Bonham; Megan H Orzalli; Kachiko Hayashi; Amaya I Wolf; Christoph Glanemann; Wolfgang Weninger; Akiko Iwasaki; David M Knipe; Jonathan C Kagan
Journal:  Cell       Date:  2014-02-13       Impact factor: 41.582

7.  Helical assembly in the MyD88-IRAK4-IRAK2 complex in TLR/IL-1R signalling.

Authors:  Su-Chang Lin; Yu-Chih Lo; Hao Wu
Journal:  Nature       Date:  2010-05-19       Impact factor: 49.962

8.  The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors.

Authors:  Tiffany Horng; Gregory M Barton; Richard A Flavell; Ruslan Medzhitov
Journal:  Nature       Date:  2002-11-21       Impact factor: 49.962

9.  Transforming binding affinities from three dimensions to two with application to cadherin clustering.

Authors:  Yinghao Wu; Jeremie Vendome; Lawrence Shapiro; Avinoam Ben-Shaul; Barry Honig
Journal:  Nature       Date:  2011-07-27       Impact factor: 49.962

10.  Binding specificity of Toll-like receptor cytoplasmic domains.

Authors:  Victoria Brown; Rachel A Brown; Adrian Ozinsky; Jay R Hesselberth; Stanley Fields
Journal:  Eur J Immunol       Date:  2006-03       Impact factor: 5.532

  10 in total
  3 in total

1.  A protocol for the systematic and quantitative measurement of protein-lipid interactions using the liposome-microarray-based assay.

Authors:  Antoine-Emmanuel Saliba; Ivana Vonkova; Samy Deghou; Stefano Ceschia; Christian Tischer; Karl G Kugler; Peer Bork; Jan Ellenberg; Anne-Claude Gavin
Journal:  Nat Protoc       Date:  2016-05-05       Impact factor: 13.491

2.  The Architecture of the TIR Domain Signalosome in the Toll-like Receptor-4 Signaling Pathway.

Authors:  Emine Guven-Maiorov; Ozlem Keskin; Attila Gursoy; Carter VanWaes; Zhong Chen; Chung-Jung Tsai; Ruth Nussinov
Journal:  Sci Rep       Date:  2015-08-21       Impact factor: 4.379

3.  Enzyme-Instructed Self-Assembly of Small D-Peptides as a Multiple-Step Process for Selectively Killing Cancer Cells.

Authors:  Jie Zhou; Xuewen Du; Natsuko Yamagata; Bing Xu
Journal:  J Am Chem Soc       Date:  2016-03-11       Impact factor: 15.419

  3 in total

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