| Literature DB >> 24766802 |
Qiufu Ma1.
Abstract
How the Merkel cell-neurite complex transduces and encodes touch remains unclear. Ikeda et al. now implicate Merkel cells as the primary sites of tactile transduction and the ion channel Piezo2 as the chief mechanotransducer. Surprisingly, Merkel cells also mediate allodynia, providing a new cellular target for chronic pain treatment.Entities:
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Year: 2014 PMID： 24766802 DOI： 10.1016/j.cell.2014.04.010
Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582