AIM: To systematically review published data on the cost-effectiveness of Fluorine-18-Fluorodeoxyglucose positron emission tomography (FDG-PET) or PET/computed tomography (PET/CT) in tumours other than lung cancer. METHODS: A comprehensive literature search of studies published in PubMed/MEDLINE, Scopus and Embase databases through the 10(th) of October in 2013 was carried out. A search algorithm based on a combination of the terms: (1) "PET" or " PET/computed tomography (PET/CT)" or "positron emission tomography"; and (2) "cost-effectiveness" or "cost-utility" or "cost-efficacy" or "technology assessment" or "health technology assessment" was used. Only cost-effectiveness or cost-utility analyses in English language were included. Exclusion criteria were: (1) articles not within the field of interest of this review; (2) review articles, editorials or letters, conference proceedings; and (3) outcome evaluation studies, cost studies or health technology assessment reports. For each included study, information was collected concerning basic study, type of tumours evaluated, perspective/type of study, results, unit and comparison alternatives. RESULTS: Sixteen studies were included. Head and neck tumours were evaluated in 4 articles, lymphoma in 4, colon-rectum tumours in 3 and breast tumours in 2. Only one article was retrieved for melanoma, oesophagus and ovary tumours. Cost-effectiveness results of FDG-PET or PET/CT ranged from dominated to dominant. CONCLUSION: Literature evidence about the cost-effectiveness of FDG-PET or PET/CT in tumours other than lung cancer is still limited. Nevertheless, FDG-PET or PET/CT seems to be cost-effective in selective indications in oncology (staging and restaging of head and neck tumours, staging and treatment evaluation in lymphoma).
AIM: To systematically review published data on the cost-effectiveness of Fluorine-18-Fluorodeoxyglucose positron emission tomography (FDG-PET) or PET/computed tomography (PET/CT) in tumours other than lung cancer. METHODS: A comprehensive literature search of studies published in PubMed/MEDLINE, Scopus and Embase databases through the 10(th) of October in 2013 was carried out. A search algorithm based on a combination of the terms: (1) "PET" or " PET/computed tomography (PET/CT)" or "positron emission tomography"; and (2) "cost-effectiveness" or "cost-utility" or "cost-efficacy" or "technology assessment" or "health technology assessment" was used. Only cost-effectiveness or cost-utility analyses in English language were included. Exclusion criteria were: (1) articles not within the field of interest of this review; (2) review articles, editorials or letters, conference proceedings; and (3) outcome evaluation studies, cost studies or health technology assessment reports. For each included study, information was collected concerning basic study, type of tumours evaluated, perspective/type of study, results, unit and comparison alternatives. RESULTS: Sixteen studies were included. Head and neck tumours were evaluated in 4 articles, lymphoma in 4, colon-rectum tumours in 3 and breast tumours in 2. Only one article was retrieved for melanoma, oesophagus and ovary tumours. Cost-effectiveness results of FDG-PET or PET/CT ranged from dominated to dominant. CONCLUSION: Literature evidence about the cost-effectiveness of FDG-PET or PET/CT in tumours other than lung cancer is still limited. Nevertheless, FDG-PET or PET/CT seems to be cost-effective in selective indications in oncology (staging and restaging of head and neck tumours, staging and treatment evaluation in lymphoma).
Authors: Juliano J Cerci; Evelinda Trindade; Valeria Buccheri; Stefano Fanti; Artur M N Coutinho; Lucia Zanoni; Camila C G Linardi; Monica Celli; Dominique Delbeke; Luís F Pracchia; Felipe A Pitela; José Soares; Pier Luigi Zinzani; José C Meneghetti Journal: Clin Lymphoma Myeloma Leuk Date: 2011-08
Authors: M Mansueto; A Grimaldi; G Mangili; M Picchio; G Giovacchini; R Viganò; C Messa; F Fazio Journal: Eur J Cancer Care (Engl) Date: 2009-06-22 Impact factor: 2.520
Authors: Martin Hetzel; Coskun Arslandemir; Hans-Helmut König; Andreas K Buck; Karin Nüssle; Gerhard Glatting; Andreas Gabelmann; Jürgen Hetzel; Vinzenz Hombach; Holger Schirrmeister Journal: J Bone Miner Res Date: 2003-12 Impact factor: 6.741